H-Profile plot using 352 genes selected from the Cho data set using equation 5 with a critical cutoff estimated using the third quartile of the simulated values of
<p><b>Copyright information:</b></p><p>Taken from "h-Profile plots for the discovery and exploration of patterns in gene expression data with an application to time course data"</p><p>http://www.biomedcentral.com/1471-2105/8/486</p><p>BMC Bioinformatics 2007;8():486-486.</p><p>Published online 20 Dec 2007</p><p>PMCID:PMC2257978.</p><p></p> The profile plots show a time series plot of the transformed gene expression values, colored according to the phase in which the maximum gene expression value occurred. A number of gene profiles on the outer edge of the bulk of the thumbnails are identified, all of which were in de Lichtenberg 's top 300 list [11] and 9 in the Cho [12] list. By the geometry of the h-profile plot these genes can be expected to have the highest variance amongst the selected genes and therefore, in the sense of de Lichtenberg , to be strongly regulated