A Fast Solution Method for Large-scale Unit Commitment Based on Lagrangian Relaxation and Dynamic Programming

The unit commitment problem (UC) is crucial for the operation and market mechanism of power systems. With the development of modern electricity, the scale of power systems is expanding, and solving the UC problem is also becoming more and more difficult. To this end, this paper proposes a new fast solution method based on Lagrangian relaxation and dynamic program-ming. Firstly, the UC solution is estimated to be an initial trial UC solution by a fast method based on Lagrangian relaxation. This initial trial UC solution fully considers the system-wide con-straints. Secondly, a dynamic programming module is introduced to adjust the trial UC solution to make it satisfy the unit-wise constraints. Thirdly, a method for constructing a feasible UC solution is proposed based on the adjusted trial UC solution. Specifically, a feasibility-testing model and an updating strategy for the trial UC solution are established in this part. Numerical tests are implemented on IEEE 24-bus, IEEE 118-bus, Polish 2383-bus, and French 6468-bus systems, which verify the effec-tiveness and efficiency of the proposed method.Comment: 10 pages, journal paper, transaction

Capacity Prediction Model Based on Limited Priority Gap-Acceptance Theory at Multilane Roundabouts

Capacity is an important design parameter for roundabouts, and it is the premise of computing their delay and queue. Roundabout capacity has been studied for decades, and empirical regression model and gap-acceptance model are the two main methods to predict it. Based on gap-acceptance theory, by considering the effect of limited priority, especially the relationship between limited priority factor and critical gap, a modified model was built to predict the roundabout capacity. We then compare the results between Raff’s method and maximum likelihood estimation (MLE) method, and the MLE method was used to predict the critical gaps. Finally, the predicted capacities from different models were compared, with the observed capacity by field surveys, which verifies the performance of the proposed model

Case report: Mononeuropathy multiplex of extranodal natural killer/T-cell lymphoma misdiagnosed as systemic vasculitis

BackgroundExtranodal NK/T-cell lymphoma (ENKTL) is an aggressive non-Hodgkin lymphoma that typically develops in the upper aerodigestive tract.Case presentationWe encountered an ENKTL patient who presented with purpura-like rashes and foot drops as initial symptoms and later developed other peripheral nerve involvement. The nerve conduction study of both the motor nerve and the sensory nerve showed axonal damage resembling mononeuropathy multiplex. Although the initial response to steroids was encouraging, the patient's symptoms reappeared and aggravated. A biopsy of the abdominal subcutaneous fat tissue with additional immunohistochemistry revealed neoplastic NK/T lymphocytes.ConclusionWe reported the first case presented as mononeuropathy multiplex as the initial clinical manifestation in ENKTL patients. Lymphoma should be considered in the diagnosis of atypical mononeuropathy in multiplex patients

Treatment of insomnia in myasthenia gravis—A prospective study on non-benzodiazepine hypnotics in the treatment of myasthenia gravis patients with insomnia

ObjectivesThis study aimed to evaluate the efficacy and safety of non-benzodiazepine hypnotics in the treatment of myasthenia gravis (MG) patients with insomnia.MethodsThis is a prospective longitudinal study. Outpatients who met the criteria for stable MG and insomnia diagnosis according to the International Classification of Sleep Disorders (third edition) were included in the study. They took a regular dose of non-benzodiazepine hypnotics (zolpidem 10 mg per night or zopiclone 7.5 mg per night) based on their own preferences. Patients received psychotherapy (including sleep health education) and were followed up for 4–5 weeks. Cases with lung diseases, respiratory disorders, or inappropriate use of hypnotic medications were excluded. The primary outcome is the difference in total Pittsburgh Sleep Quality Index (PSQI) score between baseline and the end of follow-up period. Secondary outcomes include the difference in Myasthenia Gravis Activities of Daily Living (MG-ADL) score, 7-item Generalized Anxiety Disorder Questionnaire (GAD-7), and the Patient Health Questionnaire-9 (PHQ-9) between baseline and the end of follow-up period and the safety of medication.ResultsA total of 75 MG patients with insomnia were included in this study. After 4–5 weeks of treatment, the total PSQI score and MG-ADL score were lower than baseline (p < 0.01). No patients had an increased MG-ADL score. The incidence rate of adverse events was 16.0% (12 cases), including dizziness (6 cases, 8.0%), drowsiness (3 cases, 4.0%), fatigue (2 cases, 2.7%), and nausea (1 case, 1.3%), all of which were mild. No patients had new onset breathing disorders.ConclusionNon-benzodiazepine hypnotics are safe and effective for stable MG patients who need insomnia treatment

A White Paper on Broadband Connectivity in 6G

Executive Summary This white paper explores the road to implementing broadband connectivity in future 6G wireless systems. Different categories of use cases are considered, from extreme capacity with peak data rates up to 1 Tbps, to raising the typical data rates by orders-of-magnitude, to support broadband connectivity at railway speeds up to 1000 km/h. To achieve these goals, not only the terrestrial networks will be evolved but they will also be integrated with satellite networks, all facilitating autonomous systems and various interconnected structures. We believe that several categories of enablers at the infrastructure, spectrum, and protocol/algorithmic levels are required to realize the intended broadband connectivity goals in 6G. At the infrastructure level, we consider ultra-massive MIMO technology (possibly implemented using holographic radio), intelligent reflecting surfaces, user-centric and scalable cell-free networking, integrated access and backhaul, and integrated space and terrestrial networks. At the spectrum level, the network must seamlessly utilize sub-6 GHz bands for coverage and spatial multiplexing of many devices, while higher bands will be used for pushing the peak rates of point-to-point links. The latter path will lead to THz communications complemented by visible light communications in specific scenarios. At the protocol/algorithmic level, the enablers include improved coding, modulation, and waveforms to achieve lower latencies, higher reliability, and reduced complexity. Different options will be needed to optimally support different use cases. The resource efficiency can be further improved by using various combinations of full-duplex radios, interference management based on rate-splitting, machine-learning-based optimization, coded caching, and broadcasting. Finally, the three levels of enablers must be utilized not only to deliver better broadband services in urban areas, but also to provide full-coverage broadband connectivity must be one of the key outcomes of 6G

Afterdischarges following M waves in patients with voltage-gated potassium channels antibodies

Objective: To explore the correlation between afterdischarges in motor nerve conduction studies and clinical motor hyperexcitability in patients with voltage-gated potassium channels (VGKC) antibodies. Methods: Six patients with positive serum antibodies to contactin-associated protein-like 2 (CASPR2) or/and leucine-rich glioma-inactivated protein 1 (LGI1) were recruited, including 5 with autoimmune encephalitis, and 1 with cramp-fasciculation syndrome. Electromyography (EMG), nerve conduction studies (NCS) and F waves were performed, and afterdischarges were assessed. One patient was followed up. Results: Five patients had clinical evidence of peripheral motor nerve hyperexcitability (myokymia or cramp), and four of them had abnormal spontaneous firing in concentric needle electromyography (EMG). Prolonged afterdischarges following normal M waves were present in all six patients, including the two patients who had no EMG evidence of peripheral nerve hyperexcitability (PNH). Afterdischarges disappeared after treatment with intravenous immunoglobulin (IVIG). Conclusion: The afterdischarges in motor nerve conduction study might be a sensitive indicator of peripheral motor nerve hyperexcitability in patients with VGKC antibodies. Significance: Afterdischarges in motor nerve conduction study might be more sensitive than needle electromyography for detecting peripheral motor nerve hyperexcitability, and could disappear gradually in accordance with clinical improvement and reduction of antibodies. Keywords: Afterdischarges, VGKC, Autoimmune encephalitis, Peripheral nerve hyperexcitability, F wave, M wav