Development of Nutrition Literacy Scale for Middle School Students in Chongqing, China: A Cross-Sectional Study

Background: Information on nutrition literacy of middle schoolers is limited and tools for measuring nutrition literacy of middle schoolers are inadequate. Nutrition literacy has a positive effect on health. Improving children's nutrition literacy can help them to master the necessary nutritional knowledge, develop a healthy lifestyle, and learn to supplement nutrition according to their own needs for healthy growth. Objectives: To develop the Chongqing Middle school student Nutrition Literacy Scale (CM-NLS). Methods: Three experiments were conducted. A theoretical framework and an initial item pool of CM-NLS were established based on the literature review. And the two-round Delphi method was used to explore the suitable acceptance indicators and items. Item evaluation and reduction were performed using the classical test theory. Then, the items in the final CM-NLS were tested for their validity and reliability amongst 462 middle school students. The construct validity was assessed using exploratory factor analysis (EFA) and confirmatory factor analysis (CFA). The internal consistency reliability and split-half reliability were evaluated using Cronbach's alpha coefficients. Results: The final CM-NLS consisting of 52 items that were based on three primary items (functional, interactive and critical) and six sub-items (obtain, understand, apply, interact, medial literacy and critical skill) was developed and validated. EFA suggested six factors explaining 69.44% of the total variance (Kaiser–Meyer–Olkin test = 0.916, Bartlett's test χ2 = 5,854.037, P < 0.001). CFA showed that the model fit the data adequately, with χ2/df = 1.911, root mean square error of approximation = 0.063, goodness-of-fit index = 0.822 and adjusted goodness of fit index = 0.790. The total CM-NLS Cronbach's alpha values of internal consistency and split-half reliability were 0.849 and 0.521, respectively, with reasonable reliability. Conclusions: CM-NLS is a valid and reliable instrument for assessing nutrition literacy among middle school students in Chongqing. Specifically, it could be used by practitioners for needs assessment before the implementation of a nutrition education program.This work was supported by the Chinese Nutrition Society (Science Popularization and Communication Research Fund project, Award Number CNS-SCP2020-34)

Association Between Nutrition Literacy and Overweight/Obesity of Adolescents: A Cross–Sectional Study in Chongqing, China

Objective: The burden of overweight and obesity in adolescents is increasing rapidly. This study aimed to assess the association between nutrition literacy and overweight/obesity among adolescents in China. Methods: This cross–sectional online study involving adolescents aged 10–18 years was conducted in September 2020 in 239 schools in Chongqing China. Overweight and obese adolescents were determined based on the International Obesity Task Force's recommended age–sex specific body mass index cutoff points. Nutrition literacy was measured using the “Nutrition literacy scale for middle school students in Chongqing (CM–NLS).” The CM–NLS included three subdomains (functional nutritional literacy, interactive nutrition literacy, and critical nutrition literacy). Multinomial logistic regression model was used to examine the association. Results: A total of 18,176 adolescents (49.8% girls) were included. The prevalence of overweight and obesity was 9.6% and 17.0%, respectively. Compared with those having a low nutrition literacy score (below median), those with a high score were less likely to be overweight and obese. The odds ratio (95% CI) for overweight was 0.87 (0.79–0.97) (nutrition literacy) and 0.81 (0.73–0.90) (functional nutritional literacy). The corresponding figures for obesity were 0.84 (0.77–0.91) and 0.73 (0.67–0.80), respectively. Significant interaction existed between grade and nutrition literacy. The inverse association between nutrition literacy and overweight/obesity was significant among those in senior school but not among those in junior high school. Conclusion: Nutrition literacy was inversely associated with overweight/obesity among adolescents, especially those attending senior high schools.This study was supported by the Chinese Nutrition Society (Science Popularization and Communication Research Fund project, award Number CNS–SCP2020–34)

Modality-based attention and dual-stream multiple instance convolutional neural network for predicting microvascular invasion of hepatocellular carcinoma

Background and purposeThe presence of microvascular invasion (MVI) is a crucial indicator of postoperative recurrence in patients with hepatocellular carcinoma (HCC). Detecting MVI before surgery can improve personalized surgical planning and enhance patient survival. However, existing automatic diagnosis methods for MVI have certain limitations. Some methods only analyze information from a single slice and overlook the context of the entire lesion, while others require high computational resources to process the entire tumor with a three-dimension (3D) convolutional neural network (CNN), which could be challenging to train. To address these limitations, this paper proposes a modality-based attention and dual-stream multiple instance learning(MIL) CNN.Materials and methodsIn this retrospective study, 283 patients with histologically confirmed HCC who underwent surgical resection between April 2017 and September 2019 were included. Five magnetic resonance (MR) modalities including T2-weighted, arterial phase, venous phase, delay phase and apparent diffusion coefficient images were used in image acquisition of each patient. Firstly, Each two-dimension (2D) slice of HCC magnetic resonance image (MRI) was converted into an instance embedding. Secondly, modality attention module was designed to emulates the decision-making process of doctors and helped the model to focus on the important MRI sequences. Thirdly, instance embeddings of 3D scans were aggregated into a bag embedding by a dual-stream MIL aggregator, in which the critical slices were given greater consideration. The dataset was split into a training set and a testing set in a 4:1 ratio, and model performance was evaluated using five-fold cross-validation.ResultsUsing the proposed method, the prediction of MVI achieved an accuracy of 76.43% and an AUC of 74.22%, significantly surpassing the performance of the baseline methods.ConclusionOur modality-based attention and dual-stream MIL CNN can achieve outstanding results for MVI prediction

Association between modes of delivery and postpartum dietary patterns: A cross-sectional study in Northwest China

Objective: Puerperae’ dietary patterns (DPs) during the puerperium may be influenced by the mode of delivery, but population studies on this topic are scarce. This study aims to explore the relationship between DPs and different modes of delivery among puerperae. Methods: A cross-sectional study was conducted on 3,345 parturients in Lanzhou, China. The postpartum food intake was measured by a food frequency questionnaire (FFQ). Factor analysis was used to determine the DPs. Multiple linear regression was employed to examine the association between the mode of delivery and DP. Results: In this study, two DPs, i.e., traditional and modern DPs, were identified. Traditional DP was characterized by high energy-adjusted intake of tubers, coarse cereals, rice, whole grains, fishery products, and eggs. Modern DP included a high intake of coffee, non-sugary drinks, wine, tea, and fishery products. Compared with participants with vaginal delivery (reference category), cesarean section had an inverse association with modern DP (β: −0.11, 95% CI: −0.36, −0.09). A significant interaction was found between education level, monthly household income, alcohol drinking, and modes of delivery. The inverse association between cesarean section and modern DP or the intake of coffee was significant among puerperae with higher or lower monthly household income. However, the inverse association between cesarean section and traditional DP was only found among puerperae with higher monthly household income. Moreover, among the participants with high education, cesarean section was positively associated with intake of vegetables. Conclusion: Cesarean puerperae with higher levels of education and those with lower and higher monthly household income had less unhealthy foods intake than those who had vaginal delivery. They need to be accounted for in educational programs and interventions focused on healthy diet recommendations in puerperium.This project was funded by the Chongqing Social Science Planning Project (2017YBSH057) and joint project of the Ministry of Technology and Ministry of Health (2021MSXM215) and Discipline Cultivation Fund of the First Affiliated Hospital of Chongqing Medical University. The funders had no role in the design, analysis, data interpretation and publication of findings

Preliminary comparison of tumor biologic factors in breast carcinomas from Australian and Chinese women

OBJECTIVE: To compare the morphologic and immunohistochemical properties of breast carcinomas from Chinese and Australian women in order to define possible biologic differences between these carcinomas

Exogenous ABA Enhances the Antioxidant Defense System of Maize by Regulating the AsA-GSH Cycle under Drought Stress

When drought occurs during the maize-filling period, the probability of yield decline increases. Abscisic acid (ABA) plays a regulatory role in physiological and metabolic activities during plant development. However, its effect on the antioxidant system of maize leaves during the grain-filling stage is unclear. Maize plants (Zhengdan958) were used as an experimental material, and ABA was sprayed on the leaves during the grain-filling stage. The plants were placed under drought conditions to analyze the relationship between the ascorbate-glutathione (AsA-GSH) cycle and hydrogen peroxide (H2O2) removal. Exogenous ABA significantly reduced the malondialdehyde content, relative electrolyte leakage, and H2O2 under drought stress. This is similar to the exogenous ABA effect on the AsA-GSH cycle. Exogenous ABA upregulated the transcription of related genes and alleviated the inhibition of drought stress on the monodehydroascorbate reductase and dehydroascorbate reductase activities, thereby further increasing the ascorbate peroxidase and glutathione reductase activities. It contributed to an increase in the AsA and GSH levels and inhibited the decrease in the AsA/dehydroascorbic acid and GSH/oxidized glutathione ratios. Therefore, exogenous ABA plays an important role in improving the antioxidant capacity and drought resistance physiology of maize by enhancing antioxidant enzyme activity and stabilizing the AsA and GSH redox state

Effectiveness of fly ash on the stabilization/solidification of Zn-contaminated soil

As a solid waste, the associated disposal cost of fly ash is really high. Previous studies suggested that the utilization of fly ash to treat heavy metal-contaminated soils was a new cost-effective method of disposal of it. Therefore, the effectiveness of fly ash stabilized/solidified Zn-contaminated soils has been investigated by unconfined compressive strength (UCS) and toxicity characteristics leaching procedure (TCLP) tests. Quantitative analysis of the soil microstructure was conducted by processing the X-ray diffraction (XRD) and scanning electron microscope (SEM) images. Mercury intrusion porosimetry (MIP) was carried out to illustrate the size and proportion of pore size for specimens under different ratios. The results of the tests showed an improvement in the UCS, which further increased as the content of binders was raised. Binder content would have little influence on the development of strength if the binder content exceeds a threshold value. The leached Zn2+ concentration of stabilized specimens was significantly decreased compared to that of untreated. Quantitative analysis confirmed that the addition of the binders resulted in the amount of hydration product, reduction of porosity, and a really random pores orientation, which was responsible for the improvement of the strength and leaching properties of the Zn2+ contaminated soils

Regulation of Maize Kernel Carbohydrate Metabolism by Abscisic Acid Applied at the Grain-Filling Stage at Low Soil Water Potential

A water deficit during the grain-filling stage increases the frequency of yield loss in maize (Zea mays L.). Abscisic acid (ABA) plays a regulatory role in many stages of plant growth; however, its effects on sucrose-metabolizing enzyme activities under stress are poorly understood. The activities of cell-wall-bound acid invertase, vacuolar invertase, cytoplasmic invertase, and sucrose synthase decreased continuously under drought stress, whereas ABA treatment partially restored these activities. In addition, the increase and development of sucrose content under drought stress were related to invertase activity. Up-regulation of the activities and gene expression of cell-wall-bound acid invertase and vacuolar invertase with ABA treatment contributed to the increase in the number of rows and number of grains per row. Furthermore, ABA inhibited the increase in the length of the bald tip. Compared with the control group, water stress significantly reduced the yield index, with the lowest yield index on the 10th day of stress. These results suggest that the increase in ABA-induced sucrose-metabolizing enzyme activity might be an effective mechanism to improve maize drought resistance at the grain-filling stage

Association between Selenium Intake and Optimal Sleep Duration: A National Longitudinal Study

Inconsistent findings have been discovered in studies examining the link between dietary selenium (Se) and sleep. Data were obtained from 17,176 people aged 20 and over who participated in the China Health and Nutrition Survey (CHNS) from 2004 to 2011. Face-to-face interviews were used to measure sleep duration in 2004, 2006, 2009, and 2011. To track dietary Se consumption, a 3-day, 24-h recall was undertaken. In the analysis, multilevel mixed-effects logistic regression was employed. The odds ratios (95% confidence intervals) of optimal sleep duration (7–9 h/day) in the regression of Model 4 were 1.00, 1.01 (0.89–1.15) and 1.19 (1.02–1.38) for the three tertiles of selenium consumption, respectively. Only overweight patients displayed a substantial positive connection between Se intake and the optimal sleep duration in the subgroup analysis. In summary, Se intake was significantly associated with optimal sleep duration