Educational practice as a tool in the formation of professional competence of future primary education teachers

This article is aimed at the essence, content, methods and forms of organization of training and internships in higher education institutions, as well as the formation of professional competenc

Justice in the context of sociocultural modernization of the region

В статье рассматриваются особенности восприятия справедливости в условиях постконфликтного возрождения и социокультурной модернизации региона, выделяются основные движущие силы инновационных преобразований, определяется место справедливости в иерархической структуре ценностей. В заключении делается вывод о зависимости представлений о справедливости от социального благополучия, типа общественного устройства, историко-культурного опыта. The article considers the peculiarities of justice perception in conditions of post-conflict revival and sociocultural region modernization, the basic motive forces of innovative transformations are allocated, the justice place in hierarchical structure of values is defined. In the end the conclusion about dependence of representations about justice from social well-being, type of a social system, historical and cultural experience is made

Periodic subsurface structures in GaAs formed by spatially modulated nanosecond pulse laser irradiation

We used the method of nets to calculate the thermoelastic stresses on the GaAs surface caused by a non-destructive nanosecond pulse laser irradiation (λ = 0.532 µm) with diffraction spatial intensity modulation from a shield with rectangular cut. The structure of irradiated subsurface layers of samples was studied by the AFM method. A periodic islet structure formed in the process of diffusive redistribution of defects was revealed by the level-by-level chemical etching

Algorithmization of the problem of videoscopic evaluation of the steel ropes state

The paper considers the problem of monitoring the technical state of steel ropes used in industrial and civil installations, such as elevators, cable cars, lifts, etc. To date, the assessment of the state of steel ropes and the safety of their operation is carried out mainly through visual-instrumental control, which is long in time and subject to the influence of the human factor, which determines the relevance of the task of automating this process using computer technology and artificial intelligence methods in order to improve the quality of the assessment, reducing the check interval, detecting defects in steel ropes at an early stage. The article proposes two approaches to the algorithmizing of the problem of videoscopic control of the state of steel ropes using computer vision technologies, based on software modeling of the logic of visual analysis and machine learning methods, such as deep learning artificial neural networks. The authors have developed algorithms for automatic detection of the main types of defects in images of the surface of steel ropes: increase/decrease in diameter, deformation in the form of rope, breaks in the outer wires, thermal and electric damage. The paper presents the results of preliminary testing of the developed algorithms and programs, the composition and methods for determining the main indicators for evaluating their effectiveness are proposed

The influence of Cr concentration on time resolution of GaAs detectors

Investigated in this work were the influence of Cr dopant concentration and technological conditions of doping on photoconductivity (PhC) kinetics, dependence of PhC signal magnitude on voltage applied as well as the dynamic range of a photodetector based on semi-insulating GaAs:Cr. PhC relaxation was measured using a broadband system of registration in the picosecond pulse range, which is based on the oscillograph C7-19, CCD camera and personal computer. Mechanisms of recombination that influence on fast and slow components of the PhC signal were studied. The shortest time of PhC relaxation τ ~ 2.10⁻¹⁰ s was observed in GaAs:Cr samples for the chromium dopant concentration NCr ~ 3.10¹⁷ cm−3. We have found a linear increase of the fast component of PhC with the intensity of excitation as well as a weak dependence at small levels and saturation at the high ones of excitation for the PhC slow component

Educational practice as a tool in the formation of professional competence of future primary education teachers

This article is aimed at the essence, content, methods and forms of organization of training and internships in higher education institutions, as well as the formation of professional competenc

Hibernation as a Stage of Ribosome Functioning

© 2020, Pleiades Publishing, Ltd. Abstract: In response to stress, eubacteria reduce the level of protein synthesis and either disassemble ribosomes into the 30S and 50S subunits or turn them into translationally inactive 70S and 100S complexes. This helps the cell to solve two principal tasks: (i) to reduce the cost of protein biosynthesis under unfavorable conditions, and (ii) to preserve functional ribosomes for rapid recovery of protein synthesis until favorable conditions are restored. All known genes for ribosome silencing factors and hibernation proteins are located in the operons associated with the response to starvation as one of the stress factors, which helps the cells to coordinate the slowdown of protein synthesis with the overall stress response. It is possible that hibernation systems work as regulators that coordinate the intensity of protein synthesis with the energy state of bacterial cell. Taking into account the limited amount of nutrients in natural conditions and constant pressure of other stress factors, bacterial ribosome should remain most of time in a complex with the silencing/hibernation proteins. Therefore, hibernation is an additional stage between the ribosome recycling and translation initiation, at which the ribosome is maintained in a “preserved” state in the form of separate subunits, non-translating 70S particles, or 100S dimers. The evolution of the ribosome hibernation has occurred within a very long period of time; ribosome hibernation is a conserved mechanism that is essential for maintaining the energy- and resource-consuming process of protein biosynthesis in organisms living in changing environment under stress conditions

Refractory contact to a-SiC produced by laser technology methods

Developed in the paper are method and technological scheme to obtain ohmic contacts (OC) to a-SiC(:N), Nd - Na ~1 - 3.10¹⁸ cm⁻³ by pulse laser deposition (PLD) of multilayer structures Ni/W/Si₃N₄/W and the following laser annealing (LA). When using an YAG:Nd³⁺ laser, threshold levels and optimal regimes for laser induced diffusion and laser annealing of contacts were determined. It is shown that the Q-switched regime with combined exposure of the fundamental (λ = 1.06 mm) and second (λ = 0.53 mm) harmonics are found as optimal for obtaining minimal contact resistance when YAG:Nd³⁺ laser is used. It is shown that the threshold levels of visual by observed irreversible changes in contact resistance coincide with those of current-voltage characteristics (CVC) and is found to lie in the range area PthCV = = (3 - 8)*10⁷ W*cm⁻² in dependence on thickness of deposited metal layers. The phase transition existence has been established in the process of laser induced modification and annealing on the basis of observed changes in the CVC character and results of surface investigations by Atomic Force Microscopy (AFM). Typical values of resistivity rc of non-fused OC obtained to a-SiC based on Ni/W/Si₃N₄/W structures were close to the value rc ~ (3 ÷ 4)*10⁻⁴W*cm². The contact withstood the current density 104 A*cm⁻² for 100 hours

Expression and Purification of HPF Protein from Staphylococcus aureus and Analysis of Its Structure by the Method of NMR Spectroscopy

Staphylococcus aureus hibernation-promoting factor (SaHPF) is a 22.2 kDa translation factor which under stress conditions (under amino acid starvation or antibiotic pressure) binds with the ribosome and inactivates it, thereby ensuring cell survival under stress. There are many problems with crystallization of this protein which still remain unsolved. Therefore, its analysis by NMR spectroscopy is of great interest. In this paper, we have described expression, purification, and NMR analysis of 13C/15N-labeled SaHPF protein and showed that it is present in a dimeric form in the solution. Notably, two types of signals in the NMR spectra have been observed: with weak intensity and high dispersion from N-terminal domain; with high intensity but low dispersion from a flexible loop between domains. No signals from C-terminal domain have been observed in the NMR spectra, which may indicate possible dimerization of this part of the protein. Protein dimerization has been also detected by the method of electrophoresis under native conditions