CALCULATION ALGORITHM TRUSS UNDER CRANE BEAMS

Aim.The task of reducing the deflection and increase the rigidity of single-span beams are made. In the article the calculation algorithm for truss crane girders is determined.Methods. To identify the internal effort required for the selection of cross section elements the design uses the Green's function.Results. It was found that the simplest truss system reduces deflection and increases the strength of design. The upper crossbar is subjected not only to bending and shear and compression work due to tightening tension. Preliminary determination of the geometrical characteristics of the crane farms elements are offered to make a comparison with previous similar configuration of his farms, using a simple approximate calculation methods.Conclusion.The method of sequential movements (incrementally) the two bridge cranes along the length of the upper crossbar truss beams is suggested. We give the corresponding formulas and conditions of safety

ASSESSMENT OF CYCLICAL AND STOCHASTIC WIND FLOW TO ENSURE POWER SYSTEM RELIABILITY

This article highlights current issues related to the problem of variability of wind power generation, which is becoming increasingly important as wind power’s contribution to the overall energy balance of many countries grows. Various aspects of wind flow volatility, including its random and deterministic components, are considered. The random component is associated with unpredictable changes in wind speed and direction, while the deterministic component is due to known patterns, such as daily and seasonal variations. The article proposes different methods for levelling the stochasticity of wind power flows. This is important for the stability and reliability of the power system, as it reduces the likelihood blackouts and ensures a more even distribution of load. The article also gives examples of the economic and environmental impact of using the proposed methods

确保电力系统可靠性的风流周期性和随机性评估

This article highlights current issues related to the problem of variability of wind power generation, which is becoming increasingly important as wind power’s contribution to the overall energy balance of many countries grows. Various aspects of wind flow volatility, including its random and deterministic components, are considered. The random component is associated with unpredictable changes in wind speed and direction, while the deterministic component is due to known patterns, such as daily and seasonal variations. The article proposes different methods for levelling the stochasticity of wind power flows. This is important for the stability and reliability of the power system, as it reduces the likelihood blackouts and ensures a more even distribution of load. The article also gives examples of the economic and environmental impact of using the proposed methods.Статья освещает актуальные вопросы, связанные с проблемой непостоянства выработки электроэнергии ветровых электростанций, что становится все более важным с учетом растущего вклада ветроэнергетики в общий энергобаланс многих стран. Рассматриваются различные аспекты волатильности ветрового потока, включая его случайную и детерминированную составляющие. Случайная составляющая связана с непредсказуемыми изменениями скорости и направления ветра, в то время как детерминированная составляющая обусловлена известными закономерностями, такими как суточные и сезонные колебания. В статье предложены различные методы нивелирования стохастичности энергии ветровых потоков. Это важно для обеспечения стабильности и надежности энергосистемы, так как снижает вероятность перебоев в подаче электроэнергии, обеспечивая более равномерное распределение нагрузки. В статье также приводятся примеры экономических и экологических эффектов использования предложенных методов.本文章重点介绍了当前与风电场发电变异性问题有关的问题。鉴于风能在许多国家的总体能源结构中所占比例越来越大，这一点正变得越来越重要。作者考虑了风流波动的各个方面，包括其随机和确定成分。随机成分是由于风速和风向的不可预测变化造成的，而确定成分则是由于已知模式造成的，如昼夜和季节变化。本文章提出了来平抑风流能量的随机性的多种方法。这对确保电力系统的稳定性和可靠性非常重要，因为通过提供更均匀的负荷分配，降低了停电的可能性。本文章还说明了使用拟议方法的经济和环境影响例子

Stress Coping Behavior in Civil Aviation Pilots

В статье рассмотрены современные психолого-педагогические средства формирования стресс-совладающего поведения пилотов гражданской авиации, базирующиеся на методике управления возможностями экипажа.The article deals with modern psychological and pedagogical means of forming stress-coping behaviour of civil aviation pilots, based on the methodology of Crew Resource Management

Hemispheric Asymmetry Gender Differences in Preadolescent Children

Background: Investigating various postnatal parameters of cerebral hemispheres is of great practical value.Objective: To study gender differences in hemispheric parameters and interhemispheric interactions in preadolescent children.Materials and methods: The retrospective study assessed archived brain magnetic resonance images of 60 eight-year-old boys and 60 eight-year-old girls. The analyzed parameters were as follows: 1) hemispheric length; 2) hemispheric width; 3) hemispheric height; 4) width-longitudinal index of a hemisphere; 5) altitude-longitudinal index of a hemisphere; 6) length of frontal lobes; 7) length of parietal lobes; 8) length of occipital lobes; 9) length of temporal lobes. Quantitative indicators were assessed for normal distribution using the Kolmogorov–Smirnov test. Source data were accumulated and arranged in Microsoft Excel 2016 spreadsheets. Statistica 10.0 was used for the statistical analysis. The results were considered statistically significant with P < 0.05.Results: The analysis of cephalometric indicators suggests sex-related variation in the cerebral hemispheres. Based on the obtained data we can identify morphometric parameters of interhemispheric variability that may act as one of the morphometric criteria for the brain asymmetry. The study results can be widely used for neuroimaging.Conclusions: We determined cephalometric reference values for various cerebral hemispheres parts in preadolescent children

Superconducting Receivers for Space, Balloon, and Ground-Based Sub-Terahertz Radio Telescopes

We give a review of both our own original scientific results of the development of superconducting receivers for sub-terahertz astronomy and the main leading concepts of the global instrumentation. The analysis of current astronomical problems, the results of microwave astroclimate research, and the development of equipment for sub-terahertz radio astronomy studies justify the need and feasibility of a major infrastructure project in Russia to create a sub-terahertz telescope, as well as to enhance the implementation of the ongoing Millimetron and Suffa projects. The following results are discussed: i) superconducting coherent receivers and broadband subterahertz detectors for space, balloon, and ground-based radio telescopes have been developed and tested; ii) ultrasensitive receiving systems based on tunnel structures such as superconductor-insulator-superconductor (SIS) and superconductor-insulator-normal metal-insulator-superconductor (SINIS) have been created, fabricated, and examined; iii) a receiving array based on SINIS detectors and microwave readout system for such structures has been implemented; iv) methods for manufacturing high-quality tunnel structures Nb/AlOx/Nb and Nb/AlN/NbN based on niobium films with a current density of up to 30 kA/cm(2) have been developed. Receivers operated at 200 to 950 GHz and having a noise temperature only a factor of 2 to 5 higher than the quantum limit have been created and tested

HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation.

The internal ribosome entry site (IRES) of the hepatitis C virus (HCV) drives noncanonical initiation of protein synthesis necessary for viral replication. Functional studies of the HCV IRES have focused on 80S ribosome formation but have not explored its role after the 80S ribosome is poised at the start codon. Here, we report that mutations of an IRES domain that docks in the 40S subunit's decoding groove cause only a local perturbation in IRES structure and result in conformational changes in the IRES-rabbit 40S subunit complex. Functionally, the mutations decrease IRES activity by inhibiting the first ribosomal translocation event, and modeling results suggest that this effect occurs through an interaction with a single ribosomal protein. The ability of the HCV IRES to manipulate the ribosome provides insight into how the ribosome's structure and function can be altered by bound RNAs, including those derived from cellular invaders

Estimating the impact of the Mongol expansion upon the gene pool of Tuvans

With a view to trace the Mongol expansion in Tuvinian gene pool we studied two largest Tuvinian clans – those in which, according to data of humanities, one could expect the highest Central Asian ancestry, connected with the Mongol expansion. Thus, the results of Central Asian ancestry in these two clans component may be used as upper limit of the Mongol influence upon the Tuvinian gene pool in a whole. According to the data of 59 Y-chromosomal SNP markers, the haplogroup spectra in these Tuvinian tribal groups (Mongush, N = 64, and Oorzhak, N = 27) were similar. On average, two-thirds of their gene pools (63 %) are composed by North Eurasian haplogroups (N*, N1a2, N3a, Q) connected with autochtonous populations of modern area of Tuvans. The Central Asian haplogroups (C2, O2) composed less then fifth part (17 %) of gene pools of the clans studied. The opposite ratio was revealed in Mongols: there were 10 % North Eurasian haplogroups and 75 % Central Asian haplogroups in their gene pool. All the results derived – “genetic portraits”, the matrix of genetic distances, the dendrogram and the multidimensional scaling plot, which mirror the genetic connections between Tuvinian clans and populations of South Siberia and East Asia, demonstrated the prominent similarity of the Tuvinian gene pools with populations from and Khakassia and Altai. It could be therefore assumed that Tuvinian clans Mongush and Oorzhak originated from autochtonous people (supposedly, from the local Samoyed and Kets substrata). The minor component of Central Asian haplogroups in the gene pool of these clans allowed to suppose that Mongol expansion did not have a significant influence upon the Tuvinan gene pool at a whole

Most accurate mutations in SARS-CoV-2 genomes identified in Uzbek patients show novel amino acid changes

PurposeThe rapid changes in the coronavirus genomes created new strains after the first variation was found in Wuhan in 2019. SARS-CoV-2 genotypes should periodically undergo whole genome sequencing to control it because it has been extremely helpful in combating the virus. Many diagnoses, treatments, and vaccinations have been developed against it based on genome sequencing. With its practical implications, this study aimed to determine changes in the delta variant of SARS-CoV-2 widespread in Uzbekistan during the pandemic by genome sequencing, thereby providing crucial insights for developing effective control strategies that can be directly applied in the field.DesignWe meticulously generated 17 high-quality whole-genome sequence data from 48 SARS-CoV-2 genotypes of COVID-19 patients who tested positive by PCR in Tashkent, Uzbekistan. Our rigorous approach, which includes stringent quality control measures and multiple rounds of verification, ensures the accuracy and reliability of our findings.MethodsOur study employed a unique combination of genome sequencing and bioinformatics web tools to analyze amino acid (AA) changes in the virus genomes. This approach allowed us to understand the genetic changes in the delta variant of SARS-CoV-2 widespread in Uzbekistan during the pandemic.ResultsOur study revealed significant nucleotide polymorphisms, including non-synonymous (missense) and synonymous mutations in the coding regions of the sequenced sample genomes. These findings, categorized by phylogenetic analysis into the G clade (or GK sub-clade), contribute to our understanding of the delta variant of SARS-CoV-2 widespread in Uzbekistan during the pandemic. A total of 134 mutations were identified, consisting of 65 shared and 69 unique mutations. These nucleotide changes, including one frameshift mutation, one conservative and disruptive insertion-deletion, four upstream region mutations, four downstream region mutations, 39 synonymous mutations, and 84 missense mutations, are crucial in the ongoing battle against the virus.ConclusionThe comprehensive whole-genome sequencing data presented in this study aids in tracing the origins and sources of circulating SARS-CoV-2 variants and analyzing emerging variations within Uzbekistan and globally. The genome sequencing of SARS-CoV-2 from samples collected in Uzbekistan in late 2021, during the peak of the pandemic’s second wave nationwide, is detailed here. Following acquiring these sequences, research efforts have focused on developing DNA and plant-based edible vaccines utilizing prevalent SARS-CoV-2 strains in Uzbekistan, which are currently undergoing clinical trials