Expressions of angiogenic markers and apoptotic markers in soft tissue sarcoma

Introduction: For tumor development and progression, angiogenesis and apoptosis play a crucial role. No study so far has tried to associate these two activities in tumor cells as well as correlation of both activities in the tumor and the endothelial cells. Conclusion: This study supports the role of endothelial cells in survival and regression of tumor cells in tumoregenesis. Thus, the inhibition of endothelial cells survival factor or activation ofendothelial cells death is a promising prospect as a candidate for tumor therapy. All the proteins used in this study might be potential as a useful marker for diagnosis of specific histologic subtypes especially Bcl-2 since there is diversity in expression amongst the various histologic subtypes in STS. An increase in angiogenic activity may inhibit apoptotic tumor cells death which leads to cell proliferation. However, the angiogenic activity was independent of anti-­‐apoptotic activities. A better understanding of their relations probably provides the basis for more rational cancer therapies in the future

Investigation On The Effect Of Multi Filler Loading In Graphite-Polypropylene Composite As Bipolar Plate

Materials used to fabricate the bipolar plates for Polymer Electrolyte Membrane Fuel Cell (PEMFC) need to have a good set of criteria such as light, strong, low-cost, easily fabricated, mechanically stable, and have low surface contact resistance. Additionally, PEMFC’s performance is much influenced by the materials used, type of flow channel design and shape to be fabricated on the bipolar plate surface. In this study, the fabrication of flow channel through hot compression molding method is developed. All materials used were in powder form, which are Graphite (G), Carbon black (CB) and Ferum (Fe) as fillers and the Polypropylene (PP) that acts as binder. The ratio of fillers (G/CB/Fe) and binder (PP) was fixed at 80:20. The fillers ratio was fixed in the range of (25 up to 65 wt%) G, (10 up to 30 wt%) CB and (5 up to 25 wt%) Fe and all fillers were mixed by using the ball mill machine. The second stage of mixing process is between the mixer of fillers and binder, which was mixed by using internal mixer machine. Subsequently, the compaction process through hot compression molding is done to produce G/CB/Fe/PP composite. Then, the in-plane electrical conductivity and mechanical properties such as flexure strength, bulk density and shore hardness is measure. Based on electrical conductivity, flexure strength, bulk density and shore hardness, sample with 15 wt% of Fe, has shown as the best result that is 137.39 S/cm3, 34.04 MPa, 1.582 g/cm3, 53.14 respectively. During hot compression molding process, at the same time the flow channel of serpentine type, cooling channel and the shapes of U or V shapes is pressed on the surface of the sample of bipolar plate. Thus, flow channel was investigated for accuracy of surface condition of flow channel dimensions (used coordinate measurement machine) and subsequently, compared with the actual drawings and it’s process ability. Meanwhile based on the analysis of flow channel dimensions (width, depth, rib, angle draft), the V shape is shown to give a smooth surface, with the dimensions difference between samples and drawing of about 0.118 up to 0.27%. While for the process ability, the V shape is much easier to release from the mold. As a summary, this study revealed that the flow channel dimensions (width, depth, rib, angle draft) and coling channel with V shape can be fabricated through hot compression molding method with high accuracy

THROUGH THE METAPHORICAL LENS: UNDERSTANDING OTHERING OF LANGUAGE LECTURERS IN INDONESIAN HIGHER EDUCATION

This research attempted to delve into the Indonesian and English lecturers’ views on othering experiences through the metaphorical lens. The data collection employed interviews with ten lecturers teaching at two public universities in Aceh, Indonesia. The interviews were recorded and transcribed, and further analyzed using Johnson and Lakoff’s Conceptual Metaphor Theory (CMT) where a metaphor is referred to understanding and experiencing one kind of thing in terms of another thing. The results revealed that the lecturers expressed their feelings of being othered through 14 Acehnese metaphorical expressions. They are ‘awak dalam’, ‘awak droe’ ‘asoe lhôk’, ‘Cina saboh geudông’, and ‘ureung lhap darah’,‘kön ureung gulam budée’, ‘kön awak dalam’, ‘kön awak droe jih’, ‘kön syara Ma jih’, ‘gob mat aweuk’, ‘ureung di luwa pageu’, ‘jamok di luwa keuleumbu’, ‘awak gop’, and ‘awak blah déh laôt’. Those in power (i.e., the ‘us’) discriminated against some lecturers (i.e., the ‘them’) by not providing them equal opportunities in the institution, regardless of their quality and credentials. Othering that existed in the universities negatively affected their work enthusiasm, education quality, social justice, and equality. Consequently, othering must be eradicated so that the human resources recruitment and education in universities uphold the principles of transparency, equality, and accountability

The Ability of Students in Using English Adverbs at State Politechnic of Pangkajene Kepulauan

This research is about the ability of the first year students of the Agribusiness Department in using English adverb. Based on it, it is present two problems namely: 1) How is the ability of the first year Students of the Agribusiness department in using English adverb? 2) What are the factors influencing the students’ ability in using adverbs?. To answer the question above, the writer collects data by using test and questionnaire. The data collected through the instruments were analyzed by using descriptive analysis. The result of the research shows that some of the students in Agricultural State Polytechnic of Pangkep were less interested in English, especially in using adverbs. The first year Students of the Agribusiness department can only be classified into poor. This achievement was influenced by the low of the students’ interest and the lack of the English books

THE STUDY OF THE NARRATOR IN HERMAN RN'S SHORT STORIES

This study aims to explore and strengthen the concept of narratology as one of the theories of contemporary literature. The study focuses on three aspects, namely the various forms of the narrator, the dominant type of greeting, and the unique characteristics of the work. The object of this study is 38 short stories by Herman RN which were published in various media and anthologies from 2005 to 2020. This research uses an objective approach, with qualitative-descriptive methods and content analysis techniques. The research findings are (1) the form of the narrator in the Herman RN’s short stories consisting of the first-person narrator (55.26%) and the third-person narrator (44.74%); (2) the dominant type of greeting used by the narrator who tells the story by referring to himself as "Aku = I" or "saya = I" (or other synonyms) or by referring to the object being told, such as ‘dia = he, -nya = his, (or the name of the character); and (3) the short stories have not shown certain characteristics that have become a trend in the use of these narrators. The research concludes that the storytelling system of Herman RN's short stories is simple, easy to understand, and consistent with one choice

DISFEMISME DALAM TUTURAN REMAJA BERBAHASA JAMEE DI KECEMATAN SAMADUA, KABUPATEN ACEH SELATAN

Tujuan penelitian ini adalah untuk (1) mendeskripsikan bentuk disfemisme dalam tuturan remaja berbahasa Jamee di Kecamatan Samadua, Kabupaten Aceh Selatan, (2) mendeskripsikan konteks disfemisme dalam tuturan remaja berbahasa Jamee di Kecamatan Samadua, Kabupaten Aceh Selatan, dan (3) mendeskripsikan fungsi disfemisme dalam tuturan remaja berbahasa Jamee di Kecamatan Samadua, Kabupaten Aceh Selatan. Metode yang digunakan adalah metode penelitian deskriptif dengan pendekatan kualitatif. Data penelitian ini adalah tuturan remaja yang mengandung ungkapan disfemisme dengan sumber data remaja di Kecamatan Samadua, Kabupaten Aceh Selatan. Penelitian ini menggunakan teknik simak, teknik rekam atau catat. Berdasarkan hasil analisis data, temuan penelitian ini dapat dikemukakan sebagai berikut. Pertama, remaja di Kecamatan Samadua menggunakan ungkapan disfemisme berbentuk kata, frasa, dan kalusa. Kedua, konteks penggunaan disfemisme dalam tuturan remaja di Kecamatan Samadua disebabkan karena marah, meminta, berkomentar, bercanda, bertanya, kebiasaan, terkejut, merespon pertanyaan. Ketiga, fungsi disfemisme pada tuturan remaja yaitu untuk menyakiti orang yang dituju, menuduh atau menggugat, penolokan atau pengingkaran terhadap seseorang atau sesuatu hal, mengkritik, memberi pertanyaan, mengutuk atau melaknat, dan mengekspresikan ketidakpedulian.Kata kunci: Disfemisme, Tuturan Remaja, Bahasa Jamee