3 research outputs found

    Effects of W9 and risedronate administration on Wnt/β-catenin signaling of alveolar bone in <i>OPG</i><sup><i>-/-</i></sup> mice.

    No full text
    <p>(A) Histological analysis of the interradicular septum of the first molar (M1) in maxillae from WT and <i>OPG</i><sup>–/–</sup>mice treated with and without W9 or risedronate. β-catenin staining of WT and <i>OPG</i><sup>–/–</sup>mice. β-catenin-positive cells in nuclei (brown) were observed in the M1 interradicular septum in alveolar bone areas. (B) Sclerostin and TRAP double staining of WT and <i>OPG</i><sup>–/–</sup>mice. Sclerostin-positive osteocytes (brown) were observed in the M1 interradicular septum in alveolar bone areas. Sclerostin-positive osteocytes are indicated by black arrows. (C) The number of sclerostin-positive cells/bone area (N/mm<sup>2</sup>) was determined in the M1 interradicular septum (<i>n</i> = 5). Data are expressed as the mean ± SD. *: p<0.05. Scale bar, 50 μm.</p
    corecore