1 research outputs found
Design, Synthesis, and Characterization of SO<sub>2</sub>‑Containing Azabicyclo[3.<i>n</i>.1]alkanes: Promising Building Blocks for Drug Discovery
A set
of novel SO<sub>2</sub>-containing azabicycloÂ[3.<i>n</i>.1]Âalkanes has been synthesized by the double-Mannich annulation
of of the corresponding monocyclic S-ketones. These compounds have
been rationally designed as 3D-shaped, conformationally restricted
SO<sub>2</sub>-containing building blocks for drug discovery