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    Design, Synthesis, and Characterization of SO<sub>2</sub>‑Containing Azabicyclo[3.<i>n</i>.1]alkanes: Promising Building Blocks for Drug Discovery

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    A set of novel SO<sub>2</sub>-containing azabicyclo­[3.<i>n</i>.1]­alkanes has been synthesized by the double-Mannich annulation of of the corresponding monocyclic S-ketones. These compounds have been rationally designed as 3D-shaped, conformationally restricted SO<sub>2</sub>-containing building blocks for drug discovery
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