Quantification of atherosclerotic plaque volume in coronary arteries by computed tomographic angiography in subjects with and without diabetes.

BackgroundDiabetes mellitus (DM) is considered a cardiovascular risk factor. The aim of this study was to analyze the prevalence and volume of coronary artery plaque in patients with diabetes mellitus (DM) vs. those without DM.MethodsThis study recruited consecutive patients who underwent coronary computed tomography (CT) angiography (CCTA) between October 2016 and November 2017. Personal information including conventional cardiovascular risk factors was collected. Plaque phenotypes were automatically calculated for volume of different component. The volume of different plaque was compared between DM patients and those without DM.ResultsAmong 6381 patients, 931 (14.59%) were diagnosed with DM. The prevalence of plaque in DM subjects was higher compared with nondiabetic group significantly (48.34% vs. 33.01%, χ = 81.84, P < 0.001). DM was a significant risk factor for the prevalence of plaque in a multivariate model (odds ratio [OR] = 1.465, 95% CI: 1.258-1.706, P < 0.001). The volume of total plaque and any plaque subtypes in the DM subjects was greater than those in nondiabetic patients significantly (P < 0.001).ConclusionThe coronary artery atherosclerotic plaques were significantly higher in diabetic patients than those in non-diabetic patients

Experimental realization of universal high-dimensional quantum gates with ultra-high fidelity and efficiency

Qudit, a high-dimensional quantum system, provides a larger Hilbert space to process the quantum information and has shown remarkable advantages over the qubit counterparts. It is a great challenge to realize the high fidelity universal quantum gates with qudits. Here we theoretically propose and experimentally demonstrate a set of universal quantum gates for a single optical qudit with four dimensions (including the generalized Pauli $X_4$ gate, Pauli $Z_4$ gate, and all of their integer powers), which are encoded in the polarization-spatial degree of freedom without multiple unstable cascaded interferometers. Furthermore, we also realize the controlled-$X_4$ gate and all of its integer powers. We have achieved both the ultra-high average gate fidelity $99.73\%$ and efficiency $99.47\%$, which are above the the error threshold for fault-tolerant quantum computation. Our work paves a way for the large-scale high-dimensional fault-tolerant quantum computation with a polynomial resource cost

Observation of quantum fingerprinting beating the classical limit

Quantum communication has historically been at the forefront of advancements, from fundamental tests of quantum physics to utilizing the quantum-mechanical properties of physical systems for practical applications. In the field of communication complexity, quantum communication allows the advantage of an exponential reduction in the information transmitted over classical communication to accomplish distributed computational tasks. However, to date, demonstrating this advantage in a practical setting continues to be a central challenge. Here, we report an experimental demonstration of a quantum fingerprinting protocol that for the first time surpasses the ultimate classical limit to transmitted information. Ultra-low noise superconducting single-photon detectors and a stable fibre-based Sagnac interferometer are used to implement a quantum fingerprinting system that is capable of transmitting less information than the classical proven lower bound over 20 km standard telecom fibre for input sizes of up to two Gbits. The results pave the way for experimentally exploring the advanced features of quantum communication and open a new window of opportunity for research in communication complexity and testing the foundations of physics.Comment: 19 pages, 4 figure

Domain‑wall magnetoelectric coupling in multiferroic hexagonal YbFeO\u3csub\u3e3\u3c/sub\u3e films

Electrical modulation of magnetic states in single-phase multiferroic materials, using domain-wall magnetoelectric (ME) coupling, can be enhanced substantially by controlling the population density of the ferroelectric (FE) domain walls during polarization switching. In this work, we investigate the domain-wall ME coupling in multiferroic h-YbFeO3 thin films, in which the FE domain walls induce clamped antiferromagnetic (AFM) domain walls with reduced magnetization magnitude. Simulation according to the phenomenological theory indicates that the domain-wall ME effect is dramatically enhanced when the separation between the FE domain walls shrinks below the characteristic width of the clamped AFM domain walls during the ferroelectric switching. Experimentally, we show that while the magnetization magnitude remains same for both the positive and the negative saturation polarization states, there is evidence of magnetization reduction at the coercive voltages. These results suggest that the domain-wall ME effect is viable for electrical control of magnetization