現代少女マンガにおける女性労働表象の研究 -一九七〇～二〇一〇年代の作品を中心に-

早大学位記番号:新6998早稲田大

Transient Regional Wall Motion Abnormality and Increased Wall Thickness of the Left Ventricle in Acute Myopericarditis Occurring in the Puerperium

An unusual sequence of echocardiographic abnormalities of a 25-year-old female with acute myopericarditis was described. She presented with shortness of breath and a high body temperature after the birth of her first child. Regional asynergy and increased thickness of the left ventricle were transiently observed by echocardiography. It is considered that these abnormalities resulted from inflammatory changes in heart muscle such as edema, which was ascribable to acute myopericarditis in the puerperium

A CASE OF DIABETES INSIPIDUS ACCOMPANYING THIRST DISORDER ASSOCIATED WITH HYPEROSMOLAR DIABETIC COMA

The case of a 14-year-old female who suffered from hyperosmolar diabetic coma (HODC) after resection of craniopharyngioma and during treatment for hypopituitarism and diabetes insipidus is presented. In Aug. 1989, craniopharyngioma was diagnosed and she underwent resection surgery and radiotherapy. Since then, she had been on supplemental therapy with hydrocortisone and thyroxin and desmopressin (DDAVP). On Jan. 17, 1992, she fell into HODC upon ingesting a large amount of soft drink to supplement water due to persistent polyuria. She improved quickly when supplementary fluids and insulin were administered. She had demonstrated no abnormality in glucose tolerance prior to this manifestation. Insulin therapy was deemed unnecessary after her recovery from HODC. Because of a disorder in the central nervous thirst mechaninm, she lacked the sense of thirst and concomitantly the thirst-mediated water intake in spite of elevated plasma osmolarity due to dehydration and hyperglycemia. This seemed to be the cause of her accelerating dehydration. The resulting insulin resistance then brought about her HODC. Thus, it is difficult to consider such a case of HODC as symptomatic of diabetes when no abnormality in glucose tolerance either before manifestation or after restoration can be found. It should rather be considered as a case of “dehydration hyperglycemia" and be treated as such

Synthesis, oxygen activation, and DNA-cleaving property of a histidine-pyridine-histidine ligand

A novel metal-chelating system comprising a 4-dimethylamino-　pyridine and two histidine appendages was synthesized. The two histidines were introduced by different manners; one through an amide linkage and other via a secondary amino linkage. ESR spectrum suggested a distorted pentacoordinate configuration of the copper complex of the ligand. The iron complex of the ligand had oxygen-activating property as shown by ESR spin trapping and DNA-cleaving activity as evaluated by experiments using pUC19 DNA

Risk Factors for Death among the Functionally Independent Elderly Living in Japan: A 3-Year Prospective Cohort Study

To examine risk factors for death in Japanese elderly men and women who live ordinary lives in a community, we performed a prospective cohort study in Kishimoto Town, Tottori Prefecture, Japan. In September 2001, the town population of the elderly who were 65 years and older and who lived functionally independently with or without family was 1383. We delivered questionnaires to them, and collected 1313 (94.9%) answers. Of the 1313, 29 were highly suggestive to dependent living. Subjects of the baseline survey consisted of 1284 independent elderly, excluding the 29. The subjects themselves reported answers to our questionnaire items concerning demographic variables (age, family), history of disease, homebound condition (place of daily activities), activity of daily living (walking, excreting), lifestyle (tobacco), psychology and mental status (subjective health), quality of life (domestic role) and physical status (body pain, experience of falling). They were followed-up for 3 years until August 2004. We examined correlations between their deaths during the follow-up (total number of deaths, 79: 49 men and 30 women) and potential factors for death using the Cox proportional hazard model. By the multivariate analysis of these variables, we observed that elderly men had four risk factors for death: age (hazard ratio and 95% con?dence interval; 1.09 and 1.04?1.14), subjective health (2.45 and 1.40?4.30), domestic role (2.21 and 1.22?4.01) and tobacco (1.96 and 1.10?3.48). Elderly women had two risk factors, age (1.13 and 1.07?1.20) and physical ability or skill in handling banking duties (one of competence indexes for elderly activities of daily living) (2.45 and 1.12?5.39). Most noticeably, in the present elderly Japanese living functionally independently, death was signi?cantly correlated with psychosocial factors (subjective health, domestic role) rather than physical factors (restriction of going outside due to incontinence)