HOW DOES ENTERPRISE SOCIAL MEDIA (ESM) INFLUENCE NEWCOMERS’ SOCIALIZATION: A MULTILEVEL PERSPECTIVE

Socialization plays an essential role in ensuring that newcomers to an organization enjoy greater productivity and also integrate well into their workgroups. Since the COVID-19 pandemic, enterprise social media (ESM) is increasingly being used in organizations as an informal socialization tool. However, the effectiveness of these tools in affording the necessary socialization opportunities and enabling the newcomers to better integrate within their organizational settings remains both unclear and understudied. Drawing on the extant literature on newcomer socialization within organizational behavior and the IT affordances research, this study proposes a multilevel research model to explain how various ESM affordances affect newcomers’ socialization effectiveness (i.e., performance proficiency at the individual level and group cohesion at the group level). Plans for verifying the model using two quantitative sub-studies based on the multi-source and multi-wave research design are also presented. Research implications and future research plans are also discussed

Impacts of Users’ Extra-Role Behaviors on Bright Internet Policy Adoption

Cyberspace security has been one top issue for a society. The Bright Internet (BI) based on the five principles offers a viable solution. The adoption of BI is important to the implementation of BI. A majority of the previous studies have mainly focused on access-policy violations and compliance in the past decades, while the extra-role behaviors have obtained insufficient attentions. Based on the theories of social control and accountability, this study examines the impacts of extra-role behaviors on BI policy adoption. The research findings have implications for future research and practice

Weikangning Therapy in Functional Dyspepsia and the Protective Role of Nrf2

Functional dyspepsia (FD) is a non-organic gastro-intestinal disorder that has a marked negative impact on quality of life. Compared with conventional pharmacological therapies, the traditional Chinese medicine weikangning (WKN) is a safe and effective treatment for FD. The present study aimed to determine the molecular mechanisms underlying the efficacy of WKN. The effect of different concentrations of WKN on the proliferation of the human gastric mucosal epithelial cell line GES-1 was assessed. The optimal WKN concentration to promote cell proliferation was determined, and this concentration was used to examine the effect of WKN compared with a domperidone-treated positive control group on the antioxidant capacity of GES-1 cells. The effect of WKN treatment on the growth and antioxidant activity of GES-1 cells was also assessed following nuclear factor erythroid 2 like 2 (Nrf2) knockdown. The optimal WKN dose for promoting cell growth was determined to be 0.025 mg/ml; at this concentra-tion the expression of the antioxidant proteins glutathione S-transferase P and superoxide dismutase 2 (SOD2) were significantly elevated (

EVALUATION OF HEAVY METALS AROUND THE MINING OF DECORATIVE STONE ORE IN SUSONG COUNTY LIAOHE RIVER

In order to study the pollution of heavy metals around Liaohe Fender stone mine in Susong County, the soils at six points and the sediment at four points were selected. The effects of heavy metals Cu, Zn, Pb, Cd, Cr , Ni ,Hg and As were measured, the single factor index and the Nemero index method were used to evaluate the heavy metal elements in soil and sediment. The results showed that the values of heavy metal elements in the soil and sediment were less than 1 and the Pintegrated values were less than 0.85,the mine area was not polluted by heavy metals and belonged to the clean area within the grade Ⅰ

Detection of rubidium and samarium in the atmosphere of the ultra-hot Jupiter MASCARA-4b

Ultra-hot Jupiters (UHJs) possess the most extreme environments among various types of exoplanets, making them ideal laboratories to study the chemical composition and kinetics properties of exoplanet atmosphere with high-resolution spectroscopy (HRS). It has the advantage of resolving the tiny Doppler shift and weak signal from exoplanet atmosphere and has helped to detect dozens of heavy elements in UHJs including KELT-9b, WASP-76b, WASP-121b. MASCARA-4b is a 2.8-day UHJ with an equilibrium temperature of $\sim2250$ K, which is expected to contain heavy elements detectable with VLT. In this letter, we present a survey of atoms/ions in the atmosphere of the MASCARA-4b, using the two VLT/ESPRESSO transits data. Cross-correlation analyses are performed on the obtained transmission spectra at each exposure with the template spectra generated by petitRADTRANS for atoms/ions from element Li to U. We confirm the previous detection of Mg, Ca, Cr and Fe and report the detection of Rb, Sm, Ti+ and Ba+ with peak signal-to-noise ratios (SNRs) $>$ 5. We report a tentative detection of Sc+, with peak SNRs $\sim$6 but deviating from the estimated position. The most interesting discovery is the first-time detection of elements Rb and Sm in an exoplanet. Rb is an alkaline element like Na and K, while Sm is the first lanthanide series element and is by far the heaviest one detected in exoplanets. Detailed modeling and acquiring more data are required to yield abundance ratios of the heavy elements and to understand better the common presence of them in UHJ's atmospheres.Comment: 11 pages, 7 figures, Accepted to A

Detection of TiO and VO in the atmosphere of WASP-121b and Evidence for its temporal variation

We report the transit observations of the ultra hot Jupiter WASP-121b using the Goodman High Throughput Spectrograph (GHTS) at the 4-meter ground-based telescope Southern Astrophysical Research Telescope (SOAR), covering the wavelength range $502-900$ nm. By dividing the target and reference star into 19 spectroscopic passbands and applying differential spectrophotometry, we derive spectroscopic transit light curves and fit them using Gaussian process framework to determine transit depths for every passbands. The obtained optical transmission spectrum shows a steep increased slope toward the blue wavelength, which seems to be too steep to be accounted for by the Rayleigh scattering alone. We note that the transmission spectrum from this work and other works differ obviously from each other, which was pointed out previously by \citet{Wilson2021} as evidence for temporal atmospheric variation. We perform a free chemistry retrieval analysis on the optical transmission spectra from this work and the literature HST/WFC3 NIR spectrum. We determine TiO, VO and H$_{2}$O with abundances of $-5.95_{-0.42}^{+0.47}$ dex, $-6.72_{-1.79}^{+0.51}$ dex, and $-4.13_{-0.46}^{+0.63}$ dex, respectively. We compare the abundances of all these three molecules derived from this work and previous works, and find that they are not consistent with each other, indicating the chemical compositions of the terminator region may change over long timescales. Future multi-epoch and high-precision transit observations are required to further confirm this phenomena. We note that when combining the transmission spectra in the optical and in NIR in retrieval analysis, the abundances of V and VO, the NIR-to-optical offset and the cloud deck pressure may be coupled with each other.Comment: 23 pages, 13 figures, 6 tables. Accepted for publication in Research in Astronomy and Astrophysic

Stem cell factor SALL4, a potential prognostic marker for myelodysplastic syndromes

Background: Myelodysplastic syndromes (MDS) are a group of heterogeneous diseases with variable clinical course. Predicting disease progression is difficult due to lack of specific molecular marker(s). SALL4 plays important roles in normal hematopoiesis and leukemogenesis. SALL4 transgenic mice develop MDS prior to acute myeloid leukemia (AML) transformation. However, the role of SALL4 in human MDS has not been extensively investigated. In this study, we evaluate the diagnostic/prognostic value of SALL4 in MDS by examining its expression levels in a cohort of MDS patients. Methods: Fifty-five newly diagnosed MDS, twenty MDS-AML, and sixteen post-treatment MDS patients were selected for our study along with ten healthy donors. Results: We demonstrated that SALL4 was over-expressed in MDS patients and proportionally increased in MDS patients with high grade/IPSS scores. This expression pattern was similar to that of Bmi-1, an important marker in predicting MDS/AML progression. In addition, the level of SALL4 was positively correlated with increased blast counts, high-risk keryotypes and increased significantly in MDS-AML transformation. Furthermore, higher level of SALL4 expression was associated with worse survival rates and SALL4 level decreased following effective therapy. Conclusions: To the best of our knowledge, this is the largest series and the first to report the expression pattern of SALL4 in detail in various subtypes of MDS in comparison to that of Bmi-1. We conclude that SALL4 is a potential molecular marker in predicting the prognosis of MDS