An algorithm to reduce the communication traffic for multi-word searches in a distributed hash table

In distributed hash tables, much communication traffic comes from multi-word searches. The aim of this work is to reduce the amount of traffic by using a bloom filter, which is a space-efficient probabilistic data structure used to test whether or not an element is a member of a set. However, bloom filters have a limited role if several sets have different numbers of elements. In the proposed method, extra data storage is generated when contents' keys are registered in a distributed hash table system. Accordingly, we propose a "divided bloom filter" to solve the problem of a normal bloom filter. Using the divided bloom filter, we aim to reduce both the amount of communication traffic and the amount of data storage.4th IFIP International Conference on Theoretical Computer ScienceRed de Universidades con Carreras en Informática (RedUNCI

An algorithm to reduce the communication traffic for multi-word searches in a distributed hash table

In distributed hash tables, much communication traffic comes from multi-word searches. The aim of this work is to reduce the amount of traffic by using a bloom filter, which is a space-efficient probabilistic data structure used to test whether or not an element is a member of a set. However, bloom filters have a limited role if several sets have different numbers of elements. In the proposed method, extra data storage is generated when contents' keys are registered in a distributed hash table system. Accordingly, we propose a "divided bloom filter" to solve the problem of a normal bloom filter. Using the divided bloom filter, we aim to reduce both the amount of communication traffic and the amount of data storage.4th IFIP International Conference on Theoretical Computer ScienceRed de Universidades con Carreras en Informática (RedUNCI

An Algorithm to Reduce the Communication Traffic for Multi-Word Searches in a Distributed Hash Table

Abstract. In distributed hash tables, much communication traffic comes from multi-word searches. The aim of this work is to reduce the amount of traffic by using a bloom filter, which is a space-efficient probabilistic data structure used to test whether or not an element is a member of a set. However, bloom filters have a limited role if several sets have different numbers of elements. In the proposed method, extra data storage is generated when contents' keys are registered in a distributed hash table system. Accordingly, we propose a "divided bloom filter" to solve the problem of a normal bloom filter. Using the divided bloom filter, we aim to reduce both the amount of communication traffic and the amount of data storage

An algorithm to reduce the communication traffic for multi-word searches in a distributed hash table

In distributed hash tables, much communication traffic comes from multi-word searches. The aim of this work is to reduce the amount of traffic by using a bloom filter, which is a space-efficient probabilistic data structure used to test whether or not an element is a member of a set. However, bloom filters have a limited role if several sets have different numbers of elements. In the proposed method, extra data storage is generated when contents' keys are registered in a distributed hash table system. Accordingly, we propose a "divided bloom filter" to solve the problem of a normal bloom filter. Using the divided bloom filter, we aim to reduce both the amount of communication traffic and the amount of data storage.4th IFIP International Conference on Theoretical Computer ScienceRed de Universidades con Carreras en Informática (RedUNCI

PICA communicating artery aneurysm

This report presents a rare case of such an aneurysm arising from such a communicating artery. A 66-year-old woman presented with a subarachnoid hemorrhage located predominantly in the cisterna magna with intraventricular hemorrhage. Angiography showed hypoplasia of the right posterior inferior cerebellar artery. Its vermian territory was supplied by the communicating artery from the posterior medullary segments of the left posterior inferior cerebellar artery. An aneurysm was on that communicating artery itself at a nonbranching site. The aneurysm was trapped the next day. Postoperative computed tomography showed no infarct in the right posterior inferior cerebellar artery territory. Trapping is applicable when other collateral vessels supply the contralateral posterior inferior cerebellar artery territory

A survey of support systems for return to work in Japanese companies: a cross-sectional study

The present study aimed to survey systems in Japanese companies for supporting workers returning to work from sickness absence due to mental illness. A questionnaire survey was mailed to 3,545 companies. Support systems for return to work, sick leave, and multiple sick-listed (MSL) workers were examined. A total of 161 companies responded to the survey (response rate: 4.5%). About 80% of the companies expressed difficulty in dealing with workers with mental health problems. About half of all companies reported having reset period and financial compensation systems, as well as gradual resumption and trial attendance systems. Most large companies tended to have reset period and trial attendance systems. No association was found between company size and MSL rates. The most frequent diagnosis among workers was depression, and the mean number of sick leave days was 275.3. Although there might have been a selection bias due to the low response rate, the results of this study are expected to be useful for companies when formulating employment systems

In Vitro Assessment of Factors Affecting the Apparent Diffusion Coefficient of Jurkat Cells Using Bio-phantoms

It is well known that many tumor tissues show lower apparent diffusion coefficient (ADC) values, and that several factors are involved in the reduction of ADC values. The aim of this study was to clarify how much each factor contributes to decreases in ADC values. We investigate the roles of cell density, extracellular space, intracellular factors, apoptosis and necrosis in ADC values using bio-phantoms. The ADC values of bio-phantoms, in which Jurkat cells were encapsulated by gellan gum, were measured by a 1.5-Tesla magnetic resonance imaging device with constant diffusion time of 30sec. Heating at 42℃ was used to induce apoptosis while heating at 48℃ was used to induce necrosis. Cell death after heating was evaluated by flow cytometric analysis and electron microscopy. The ADC values of bio-phantoms including non-heated cells decreased linearly with increases in cell density, and showed a steep decline when the distance between cells became less than 3μm. The analysis of ADC values of cells after destruction of cellular structures by sonication suggested that approximately two-thirds of the ADC values of cells originate from their cellular structures. The ADC values of bio-phantoms including necrotic cells increased while those including apoptotic cells decreased. This study quantitatively clarified the role of the cellular factors and the extracellular space in determining the ADC values produced by tumor cells. The intermediate diffusion time of 30msec might be optimal to distinguish between apoptosis and necrosis

Pancreatic RECK inactivation promotes cancer formation, epithelial-mesenchymal transition, and metastasis

膵癌悪性化の分子機構解明 --RECK発現の低下が膵癌の浸潤・転移を引き起こす--. 京都大学プレスリリース. 2023-09-19.RECK is downregulated in various human cancers; however, how RECK inactivation affects carcinogenesis remains unclear. We addressed this issue in a pancreatic ductal adenocarcinoma (PDAC) mouse model and found that pancreatic Reck deletion dramatically augmented the spontaneous development of PDAC with a mesenchymal phenotype, which was accompanied by increased liver metastases and decreased survival. Lineage tracing revealed that pancreatic Reck deletion induced epithelial-mesenchymal transition (EMT) in PDAC cells, giving rise to inflammatory cancer-associated fibroblast–like cells in mice. Splenic transplantation of Reck-null PDAC cells resulted in numerous liver metastases with a mesenchymal phenotype, whereas reexpression of RECK markedly reduced metastases and changed the PDAC tumor phenotype into an epithelial one. Consistently, low RECK expression correlated with low E-cadherin expression, poor differentiation, metastasis, and poor prognosis in human PDAC. RECK reexpression in the PDAC cells was found to downregulate MMP2 and MMP3, with a concomitant increase in E-cadherin and decrease in EMT-promoting transcription factors. An MMP inhibitor recapitulated the effects of RECK on the expression of E-cadherin and EMT-promoting transcription factors and invasive activity. These results establish the authenticity of RECK as a pancreatic tumor suppressor, provide insights into its underlying mechanisms, and support the idea that RECK could be an important therapeutic effector against human PDAC