4,103 research outputs found
Minimum-error discrimination between symmetric mixed quantum states
We provide a solution of finding optimal measurement strategy for
distinguishing between symmetric mixed quantum states. It is assumed that the
matrix elements of at least one of the symmetric quantum states are all real
and nonnegative in the basis of the eigenstates of the symmetry operator.Comment: 10 page
Phylogenetic characterization and promoter expression analysis of a novel hybrid protein disulfide isomerase/cargo receptor subfamily unique to plants and chromalveolates
Light atom quantum oscillations in UC and US
High energy vibrational scattering in the binary systems UC and US is
measured using time-of-flight inelastic neutron scattering. A clear set of
well-defined peaks equally separated in energy is observed in UC, corresponding
to harmonic oscillations of the light C atoms in a cage of heavy U atoms. The
scattering is much weaker in US and only a few oscillator peaks are visible. We
show how the difference between the materials can be understood by considering
the neutron scattering lengths and masses of the lighter atoms. Monte Carlo ray
tracing is used to simulate the scattering, with near quantitative agreement
with the data in UC, and some differences with US. The possibility of observing
anharmonicity and anisotropy in the potentials of the light atoms is
investigated in UC. Overall the observed data is well accounted for by
considering each light atom as a single atom isotropic quantum harmonic
oscillator.Comment: 10 pages, 8 figure
Engaging students for the learning and assessment of the advanced computer graphics module using the latest technologies
© WIARS, 2017The advanced computer graphics has been one of the most basic and landmark modules in the field of computer science. It usually covers such topics as core mathematics, lighting and shading, texture mapping, colour and depth, and advanced modeling. All such topics involve mathematics for object modeling and transformation, and programming for object visualization and interaction. While some students are not as good in either mathematics or programming, it is usually a challenge to teach computer graphics to these students effectively. This is because it is difficult for students to link mathematics and programming with what they used to see in video games and the TV advertisements for example and thus they can easily be put off. In this paper, we investigate how the latest technologies can help alleviate the teaching and learning tasks. Instead of selecting the low level programming languages for demonstration and assignment such as Java, Java 3D, C++, or OpenGL, we selected Three.js, which is one of the latest and freely accessible 3D graphics libraries. It has a unique advantage that it provides a seamless interface between the main stream web browsers and 2D/3D graphics. The developed code can be run on a web browser such as Firefox, Chrome, or Safari for testing, debugging and visualization without code changing. The unique design patterns and objectives of Three.js can be very attractive to third party software houses to develop auxiliary functions, methods and tutorials and to make them freely available for the public. Such a unique property of Three.js and its widely available supporting resources are especially helpful to engage students, inspire their learning and facilitate teaching. To evaluate the effectiveness for using Three.js in teaching computer graphics we have set up an assignment for scene modeling in the last 4 years with focuses on the quality of the simulated scene (50%) and the quality of the assignment report (50%). We have evaluated different assessment forms of the module that we taught in the last four years: in 2013-2014 the module consisted of 20% assignment and 80% exam based on Java 3D; in 2014-2015 the same proportion of assignment/exam but based on WebGL, in 2015-2016 the module was 50-50% of assignment and exam but based on Three.js; and in this year the module is 100% assignment based on Three.js. The effectiveness of the module delivery has been evaluated both qualitatively and quantitatively from five aspects: a) average marks of students, b) moderator report, c) module evaluation questionnaire, d) external examiner’s comments and e) examination board recommendations. The results have shown that Three.js is indeed more successful in engaging students for learning and the 100% assignment assessment enables students to focus more on the design and development. This four year result is really encouraging to us as an educational institute to embrace the latest technologies for the delivery of such challenging modules as computer graphics and machine learning
Global-local visual processing impacts risk taking behaviors, but only at first
We investigated the impact of early visual processing on decision-making during unpredictable, risky situations. Participants undertook Navon’s (1977) task and attended to either global letters or local letters only, following which they completed the Balloon Analogue Risk Task (BART). It was observed that global-focused individuals made more balloon pumps during the BART (i.e., took more risk), whereas local-focused individuals took less risk, albeit only initially. The theory of predictive and reactive control systems (PARCS) provides an excellent account of the data. Implications and future directions are discussed
Clustering of childhood leukaemia in Hong Kong: association with the childhood peak and common acute lymphoblastic leukaemia and with population mixing.
Incidence data of childhood leukaemia (CL) in Hong Kong (1984-90) have been analysed for evidence of variation between small areas. All cases (n=261) were classified by morphological cell type, with the majority (n=205) being acute lymphoblastic leukaemia (ALL), and haematological review has permitted immunophenotypic classification for 73% of these. The data have been examined for evidence of spatial clustering within small census areas (TPUs) and for association with population mixing, with attention focused on those subgroups (especially the childhood peak of ALL--taken here to be diagnoses in children from 24 months up to the seventh birthday--and common ALL) which, it has been hypothesized, may be caused by unusual patterns of exposure and response to common infections. For the whole of Hong Kong, there was evidence of spatial clustering of ALL at ages 0-4 years (P = 0.09) and in the childhood peak (P<0.05). When these analyses were restricted to TPUs where extreme population mixing may have occurred, overall incidence was elevated and significant evidence of clustering was found for ALL (P<0.007) at these ages and for the common ALL in the childhood peak (P = 0.032). Replication of the analyses for subsets of leukaemia that were not dominated by the childhood peak of ALL found no evidence of clustering. This is the first investigation of an association between population mixing and childhood leukaemia in Asia and the first to include clustering and to consider particular subsets. The results are supportive of the 'infectious' aetiology hypothesis for subsets of childhood leukaemia, specifically common ALL in the childhood peak
A targeted gene panel that covers coding, non-coding and short tandem repeat regions improves the diagnosis of patients with neurodegenerative diseases
Genetic testing for neurodegenerative diseases (NDs) is highly challenging because of genetic heterogeneity and overlapping manifestations. Targeted-gene panels (TGPs), coupled with next-generation sequencing (NGS), can facilitate the profiling of a large repertoire of ND-related genes. Due to the technical limitations inherent in NGS and TGPs, short tandem repeat (STR) variations are often ignored. However, STR expansions are known to cause such NDs as Huntington\u27s disease and spinocerebellar ataxias type 3 (SCA3). Here, we studied the clinical utility of a custom-made TGP that targets 199 NDs and 311 ND-associated genes on 118 undiagnosed patients. At least one known or likely pathogenic variation was found in 54 patients; 27 patients demonstrated clinical profiles that matched the variants; and 16 patients whose original diagnosis were refined. A high concordance of variant calling were observed when comparing the results from TGP and whole-exome sequencing of four patients. Our in-house STR detection algorithm has reached a specificity of 0.88 and a sensitivity of 0.82 in our SCA3 cohort. This study also uncovered a trove of novel and recurrent variants that may enrich the repertoire of ND-related genetic markers. We propose that a combined comprehensive TGPs-bioinformatics pipeline can improve the clinical diagnosis of NDs
Quantum Detection with Unknown States
We address the problem of distinguishing among a finite collection of quantum
states, when the states are not entirely known. For completely specified
states, necessary and sufficient conditions on a quantum measurement minimizing
the probability of a detection error have been derived. In this work, we assume
that each of the states in our collection is a mixture of a known state and an
unknown state. We investigate two criteria for optimality. The first is
minimization of the worst-case probability of a detection error. For the second
we assume a probability distribution on the unknown states, and minimize of the
expected probability of a detection error.
We find that under both criteria, the optimal detectors are equivalent to the
optimal detectors of an ``effective ensemble''. In the worst-case, the
effective ensemble is comprised of the known states with altered prior
probabilities, and in the average case it is made up of altered states with the
original prior probabilities.Comment: Refereed version. Improved numerical examples and figures. A few
typos fixe
Relating Quantum Information to Charged Black Holes
Quantum non-cloning theorem and a thought experiment are discussed for
charged black holes whose global structure exhibits an event and a Cauchy
horizon. We take Reissner-Norstr\"{o}m black holes and two-dimensional dilaton
black holes as concrete examples. The results show that the quantum non-cloning
theorem and the black hole complementarity are far from consistent inside the
inner horizon. The relevance of this work to non-local measurements is briefly
discussed.Comment: 14 pages, 2 figure
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