1,207 research outputs found
Detecting non-Markovian plasmonic band gaps in quantum dots using electron transport
Placing a quantum dot close to a metal nanowire leads to drastic changes in
its radiative decay behavior because of evanescent couplings to surface
plasmons. We show how two non-Markovian effects, band-edge and retardation,
could be observed in such a system. Combined with a quantum dot p-i-n junction,
these effects could be readout via current-noise measurements. We also discuss
how these effects can occur in similar systems with restricted geometries, like
phononic cavities and photonic crystal waveguides. This work links two
previously separate topics: surface-plasmons and current-noise measurements.Comment: 8 page
Transcriptional Response of Selenopolypeptide Genes and Selenocysteine Biosynthesis Machinery Genes in Escherichia coli during Selenite Reduction
This work was supported by a United States Department of Agriculture-Cooperative State Research, Education, and Extension Service grant (no. 2009-35318-05032), a Biotechnology Research grant (no. 2007-BRG-1223) from the North Carolina Biotechnology Center, and a startup fund from the Golden LEAF Foundation to the Biomanufacturing Research Institute and Technology Enterprise (BRITE).Bacteria can reduce toxic selenite into less toxic, elemental selenium (Se0), but the mechanism on how bacterial cells reduce selenite at molecular level is still not clear. We used Escherichia coli strain K12, a common bacterial strain, as a model to study its growth response to sodium selenite (Na2SeO3) treatment and then used quantitative real-time PCR (qRT-PCR) to quantify transcript levels of three E. coli selenopolypeptide genes and a set of machinery genes for selenocysteine (SeCys) biosynthesis and incorporation into polypeptides, whose involvements in the selenite reduction are largely unknown. We determined that 5 mM Na2SeO3 treatment inhibited growth by ∼50% while 0.001 to 0.01 mM treatments stimulated cell growth by ∼30%. Under 50% inhibitory or 30% stimulatory Na2SeO3 concentration, selenopolypeptide genes (fdnG, fdoG, and fdhF) whose products require SeCys but not SeCys biosynthesis machinery genes were found to be induced ≥2-fold. In addition, one sulfur (S) metabolic gene iscS and two previously reported selenite-responsive genes sodA and gutS were also induced ≥2-fold under 50% inhibitory concentration. Our findings provide insight about the detoxification of selenite in E. coli via induction of these genes involved in the selenite reduction process.Publisher PDFPeer reviewe
Quantum chaos and critical behavior on a chip
The Dicke model describes N qubits (or two-level atoms) homogenously coupled
to a bosonic mode. Here we examine an open-system realization of the Dicke
model, which contains critical and chaotic behaviour. In particular, we extend
this model to include an additional open transport qubit (TQ) (coupled to the
bosonic mode) for passive and active measurements. We illustrate how the
scaling (in the number of qubits N) of the superradiant phase transition can be
observed in both current and current-noise measurements through the transport
qubit. Using a master equation, we also investigate how the phase transition is
affected by the back-action from the transport qubit and losses in the cavity.
In addition, we show that the non-integrable quantum chaotic character of the
Dicke model is retained in an open-system environment. We propose how all of
these effects could been seen in a circuit QED system formed from an array of
superconducting qubits, or an atom chip, coupled to a quantized resonant cavity
(e.g., a microwave transmission line).Comment: 7 page
Local constraints in programming languages part I: syntax
AbstractThe method of local constraints attempts to describe context-free languages in an apparently context-sensitive form which helps to retain the intuitive insights about the grammatical structure. This form of description, while apparently context-sensitive is, in fact, context-free and allows a program derivation structure to be represented as a tree with additional constraints, thus allowing for the possibility of a correctness proof in the form of Knuthian semantics. These semantic aspects will be discussed in a sequel to this paper (Part II: Semantics). Several detailed examples are given to motivate the use of local constraints grammars including some examples from the syntax of ALGOL 60. A parsing algorithm has been described; its purpose is to show that the computation of local constraints is quite reasonable. Transformation rules for transferring a context-free grammar into a local constraints grammar have been described and some heuristic approaches for the inverse transformation have been presented
Rainfall Reliability Evaluation for Stability of Municipal Solid Waste Landfills on Slope
[[abstract]]A method to assess the reliability for the stability of municipal solid waste (MSW) landfills on slope due to rainfall infiltration is proposed. Parameter studies are first done to explore the influence of factors on the stability of MSW. These factors include rainfall intensity, duration, pattern, and the engineering properties of MSW. Then 100 different combinations of parameters are generated and associated stability analyses of MSW on slope are performed assuming that each parameter is uniform distributed around its reason ranges. In the following, the performance of the stability of MSW is interpreted by the artificial neural network (ANN) trained and verified based on the aforementioned 100 analysis results. The reliability for the stability of MSW landfills on slope is then evaluated and explored for different rainfall parameters by the ANN model with first-order reliability method (FORM) and Monte Carlo simulation (MCS).[[incitationindex]]SCI[[booktype]]紙
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Workplace secondhand smoke exposure in the U.S. trucking industry.
BackgroundAlthough the smoking rate in the United States is declining because of an increase of smoke-free laws, among blue-collar workers it remains higher than that among many other occupational groups.ObjectivesWe evaluated the factors influencing workplace secondhand smoke (SHS) exposures in the U.S. unionized trucking industry.MethodsFrom 2003 through 2005, we measured workplace SHS exposure among 203 nonsmoking and 61 smoking workers in 25 trucking terminals. Workers in several job groups wore personal vapor-phase nicotine samplers on their lapels for two consecutive work shifts and completed a workplace SHS exposure questionnaire at the end of the personal sampling.ResultsMedian nicotine level was 0.87 microg/m3 for nonsmokers and 5.96 microg/m3 for smokers. As expected, smokers experienced higher SHS exposure duration and intensity than did nonsmokers. For nonsmokers, multiple regression analyses indicated that self-reported exposure duration combined with intensity, lack of a smoking policy as reported by workers, having a nondriver job, and lower educational level were independently associated with elevated personal nicotine levels (model R2 = 0.52). Nondriver job and amount of active smoking were associated with elevated personal nicotine level in smokers, but self-reported exposure, lack of a smoking policy, and lower educational level were not.ConclusionsDespite movements toward smoke-free laws, this population of blue-collar workers was still exposed to workplace SHS as recently as 2005. The perceived (reported by the workers), rather than the official (reported by the terminal managers), smoking policy was associated with measured SHS exposure levels among the nonsmokers. Job duties and educational level might also be important predictors of workplace SHS exposure
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A Systemwide Electronic Health Record Checklist to Improve Comorbidity Screening of Children With Inflammatory Bowel Disease.
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Secondhand smoke exposure and inflammatory markers in nonsmokers in the trucking industry.
BackgroundFew studies have directly assessed the association of secondhand smoke (SHS) with cardiovascular disease-related inflammatory markers, and the findings are inconsistent.ObjectivesWe assessed the association between SHS exposure and the inflammatory markers high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6), and soluble intercellular adhesion molecule-1 (sICAM-1) in 199 nonsmoking U.S. trucking industry workers.MethodsParticipants provided blood samples either by mail (blood drawn at local health care provider near home) or at the work site (blood drawn by research staff on-site) and completed a health and work history questionnaire at the time of blood draw. Exposure to SHS was measured by plasma cotinine concentrations. We used multivariate regression analyses to assess the associations between levels of cotinine and inflammatory markers.ResultsThe median cotinine level was 0.10 ng/mL (interquartile range, 0.04-0.23 ng/mL). The odds ratios of elevated hs-CRP (above highest CRP tertile, 1.5 mg/L) were 2.85 [95% confidence interval (CI), 1.03-7.89] for the high-cotinine group (> 0.215 ng/mL) and 2.80 (95% CI, 1.11-7.10) for the moderate-cotinine group (0.05-0.215 ng/mL), compared with the low-cotinine group (< 0.05 ng/mL), adjusting for age, sex, race, educational level, obesity, previous smoking history, job title, and medical history. Plasma cotinine levels were not associated with IL-6 or sICAM-1.ConclusionsSHS exposure, as assessed by plasma cotinine, was positively associated with hs-CRP in this group of blue-collar workers. The strength of the association with hs-CRP depended on the cut points selected for analysis
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