Trace and Edit Relation Associations in GPT

This study introduces a novel approach for analyzing and modifying entity relationships in GPT models, diverging from ROME's entity-focused methods. We develop a relation tracing technique to understand the influence of language model computations on relationship judgments. Using the FewRel dataset, we identify key roles of MLP modules and attention mechanisms in processing relationship information. Our method, tested against ROME on a new dataset, shows improved balance in specificity and generalization, underscoring the potential of manipulating early-layer modules for enhanced model understanding and accuracy

Ultra-Sensitive Piezo-Resistive Sensors Constructed with Reduced Graphene Oxide/Polyolefin Elastomer (RGO/POE) Nanofiber Aerogels.

Flexible wearable pressure sensors have received extensive attention in recent years because of the promising application potentials in health management, humanoid robots, and human machine interfaces. Among the many sensory performances, the high sensitivity is an essential requirement for the practical use of flexible sensors. Therefore, numerous research studies are devoted to improving the sensitivity of the flexible pressure sensors. The fiber assemblies are recognized as an ideal substrate for a highly sensitive piezoresistive sensor because its three-dimensional porous structure can be easily compressed and can provide high interconnection possibilities of the conductive component. Moreover, it is expected to achieve high sensitivity by raising the porosity of the fiber assemblies. In this paper, the three-dimensional reduced graphene oxide/polyolefin elastomer (RGO/POE) nanofiber composite aerogels were prepared by chemical reducing the graphene oxide (GO)/POE nanofiber composite aerogels, which were obtained by freeze drying the mixture of the GO aqueous solution and the POE nanofiber suspension. It was found that the volumetric shrinkage of thermoplastic POE nanofibers during the reduction process enhanced the compression mechanical strength of the composite aerogel, while decreasing its sensitivity. Therefore, the composite aerogels with varying POE nanofiber usage were prepared to balance the sensitivity and working pressure range. The results indicated that the composite aerogel with POE nanofiber/RGO proportion of 3:3 was the optimal sample, which exhibits high sensitivity (ca. 223 kPa-1) and working pressure ranging from 0 to 17.7 kPa. In addition, the composite aerogel showed strong stability when it is either compressed with different frequencies or reversibly compressed and released 5000 times

Utilization of National Essential Public Health Services and Its Relationship with Management Effect in Chinese Type 2 Diabetic Patients

BackgroundThe national essential public health services (NEPHS) , which have been implemented since 2009, may be the largest population-based intervention practice for Chinese patients with diabetes currently. It is important to understand the utilization and management effect of such services in diabetic population over this period of more than 10 years of development.ObjectiveTo understand the utilization and management effect of NEPHS as well as their association in Chinese type 2 diabetics.MethodsBy use of multi-stage stratified sampling, 1 527 type 2 diabetics (≥35 years old) were selected from 20 community (township) health centers in 10 districts (counties) of 5 cities in eastern, central and western China during November to December 2019. Sociodemographic characteristics, utilization and management effect of NEPHS in these patients were collected by face-to-face surveys with a self-designed questionnaire.ResultsAccording to the survey, patients' self-reported rates of creating health records, use of health records, undergoing standardized blood glucose tests, and receiving standard follow-ups were 90.34% (1 375/1 522) , 52.80% (725/1 373) , 83.69% (1 262/1 508) , and 90.18% (1 377/1 527) , respectively. Household follow-ups and hospital follow-ups accounted for 29.24% (443/1 515) and 61.06% (925/1 515) of the total last follow-ups, respectively. The analysis of management effect showed that patients' self-reported rates of home-based self-monitoring blood glucose and regular medication in the past 6 months were 53.57% (818/1 527) , and 89.26% (1 363/1 527) , respectively. The rates of patients who were satisfied with glycemic control, and overall medical services assessed in the last follow-up were 65.23% (996/1 527) , and 95.15% (1 453/1 527) , respectively. In those≥65 years old, the prevalence of home-based self-monitoring blood glucose differed significantly by the creation of health records and Chinese medicine services (P<0.05) . The prevalence of regular medication differed significantly by number of follow-ups (P<0.05) . The level of overall satisfaction with services differed significantly by the access to personal medical records at any time, Chinese medicine services, number of home-based self-monitoring blood glucose, and type of follow-up (P<0.05) . In those aged from 35 to 64, the prevalence of home-based self-monitoring blood glucose differed significantly by the creation of health records, access to personal medical records at any time, Chinese medicine services, number of blood glucose testing, and number of follow-ups (P<0.05) . The prevalence of regular medication differed significantly by the type of follow-up (P<0.05) . The satisfaction rate of blood glucose control differed significantly by access to personal medical records at any time (P<0.05) . The overall service satisfaction rate differed significantly by follow-up type and creation of health records (P<0.05) .ConclusionNEPHS have influenced community-based management of type 2 diabetic patients, the standard implementation of which has enhanced the management effect and the overall service satisfaction in these patients

NaoXinTong Inhibits the Development of Diabetic Retinopathy in d

Buchang NaoXinTong capsule (NXT) is a Chinese Materia Medica standardized product extracted from 16 Chinese traditional medical herbs and widely used for treatment of patients with cerebrovascular and cardiovascular diseases in China. Formation of microaneurysms plays an important role in the development of diabetic retinopathy. In this study, we investigated if  NXT can protect diabetic mice against the development of diabetic retinopathy. The db/db mice (~6 weeks old), a diabetic animal model, were divided into two groups and fed normal chow or plus NXT for 14 weeks. During the treatment, fasting blood glucose levels were monthly determined. After treatment, retinas were collected to determine retinal thickness, accumulation of carbohydrate macromolecules, and caspase-3 (CAS-3) expression. Our results demonstrate that administration of NXT decreased fasting blood glucose levels. Associated with the decreased glucose levels, NXT blocked the diabetes-induced shrink of multiple layers, such as photoreceptor layer and outer nuclear/plexiform layers, in the retina. NXT also inhibited the diabetes-induced expression of CAS-3 protein and mRNA, MMP-2/9 and TNFα mRNA, accumulation of carbohydrate macromolecules, and formation of acellular capillaries in the retina. Taken together, our study shows that NXT can inhibit the development of diabetic retinopathy and suggests a new potential application of NXT in clinic

Study on Yield Stress and Thixotropy of Hydroxypropyl Distarch Phosphate Paste

In order to study the yield stress and thixotropic behavior of the hydroxypropyl distarch phosphate (HPDSP) paste, HPDSP respectively derived from corn starch (CS) and waxy corn starch (WS) with different ratios of amylopectin were investigated. The critical mass fractions, yield stress, and thixotropic behavior of HPDSP pastes under various temperatures were studied. The results showed that, the critical mass fractions for the transition of the HPDSP solution at 5 ℃ from dilute to semi-dilute, and from semi-dilute to concentrated were 3wt% and 6wt%, respectively. The yield stress of 5wt% corn starch-hydroxypropyl distarch phosphate (CS-HPDSP) and waxy corn starch-hydroxypropyl distarch phosphate (WS-HPDSP) paste both showed weak correlations with temperature. However, at 6wt% concentration, the yield stress significantly decreased (P<0.05) by 69.52% and 77.95% respectively at 85 ℃. Additionally, the thixotropic behavior of HPDSP was influenced by both mass fraction and temperature. At 5 ℃, 5wt% CS-HPDSP and WS-HPDSP showed limited thixotropy, while at 6wt% of mass fraction, the areas of thixotropic loops of CS-HPDSP and WS-HPDSP were 163.49 and 85.00 Pa/s, respectively, and decreased by 86.38% and 92.18% at 85 ℃, respectively. WS-HPDSP exhibited less thixotropic behavior than CS-HPDSP, and showed better stability in three interval thixotropy test (3iTT). In conclusion, WS-HPDSP showed less yield stress and thixotropy compared with CS-HPDSP. This study provides theoretical supports for practical application of HPDSP as thickening agents in food products