Frequency responses of rat retinal ganglion cells

<div>This repository contains the data associated with the manuscript, "Frequency responses of rat retinal ganglion cells", by Alex E. Hadjinicolaou et al., published in PLOS ONE. There are three components:</div><div><br></div><div>* recordings: whole-cell recordings from retinal ganglion cells (RGCs) [recordings.7z];</div><div>* reconstructions: morphological reconstructions from a subset of the recorded RGCs [ANU.7z | NVRI, part 1-3.7z]; and</div><div>* figures: MATLAB code used to generate the manuscript figures.</div><div><br></div><div>Note that there is not always a 1-1 relationship between the recording name (e.g. 050211r1c3) and the Cell ID associated with the reconstruction (in this case, 20110502_c2). The Excel sheet "recordings" within the file "data summary.xlsx" lists these associations. The "morphology" sheet within the same file contains the soma/dendritic field data obtained from measurements made using FIJI, an ImageJ-based analysis program. Morphological classification was guided by Sun W, Li N, He S. Large-scale morophological survey of rat retinal ganglion cells. Vis Neurosci. 2002;19: 483–493.</div

The effect of soma size on the frequency response of retinal ganglion cells.

<p>Panels (A–D) show the mean frequency response of A2, C2, D1 and D2 RGC types, respectively. Within each RGC type, cells are grouped and their frequency responses averaged according to their soma diameter. Within each RGC type, cells with the largest soma diameters are shown in black and those with the smallest soma diameters are shown in grey. For comparison, the frequency response, averaged over all cells of a given type, irrespective of soma diameter, is shown by the dashed line. Panels (E–H) show distributions of soma diameter for each of the A2, C2, D1 and D2 RGC types, respectively.</p

Intrinsic Physiological Properties of RGC Subtypes.

<p>Intrinsic Physiological Properties of RGC Subtypes.</p