USE OF RENEWABLE ENERGY SOURCES FOR LIGHTING TRAILS

В работе рассмотрен вопрос возможности освещения автомобильных дорог от альтернативных источников энергии. Показана энергетическая, экономическая и экологическая целесообразность данного решения.The paper considers the possibility of lighting roads from alternative energy sources. The energy, economic and environmental feasibility of this solution is shown

Chemistry for Sustainable Development 18 (2010) 581601 Inhibitors of Nitric Oxide Synthases: the Chemical Aspect of the Problem

Abstract Different classes of compounds exhibiting the properties of inhibitors for NO synthases are considered in the review. Literature data on n atural and synthetic agents published between the years 2003 and 2009 are an alyzed and systematized

Significance of the internal picture of the disease for the creation of an individual rehabilitation or habilitation program for people with disabilities

The internal picture of the disease is “everything that is experienced and underwent by the patient. The whole complex of feelings, the general state of health, self-observation, his idea of his illness, its causes ... the entire vast world of the patient, which consists of the very complex combinations of perception and sensation, emotions, affects, conflicts, mental experiences and traumas” [4–6]. The internal picture of the disease should be viewed as a single acting system, all components of which are closely interrelated and constantly interact with each other. When analysing the structure of the internal picture of the disease, it is important not only to separate its individual components, but also to differentiate them

Chemistry for Sustainable Development 17 (2009) 507511 501 Seasonal Dynamics of Riccardin C Accumulation in Primula macrocalyx Bge

Abstract Season al dyn amics has been studied for a metabolite accumulation in Primula macrocalyx Bge. with respect to its major component, bisbibenzyl riccardin C 1, an inhibitor of inducible NO synthase. Seven introduced populations of the plant have been investigated. A wild-growing P. macrocalyx population was used as a reference. It has been demonstrated the harvesting of plant raw material for the purpose of bisbenzyl 1 isolation is appropriate for carrying out after plant flowering, during the fruiting stage. Besides, in the course of the investigation there were 3′, 4′, 5′-trimethoxyflavone 2 and perrottetin Å 3 isolated from the acetone extract of P. macrocalyx

Study of the Stability of a Viscous Solution of Naftifin Hydrochloride with a Combination of Polyethylene Glycols for External Use

Introduction. An innovative antifungal viscous solution based on naftifine hydrochloride with a combination of polyethylene glycols (PEG) was developed in the laboratory of Sechenov University. The developed preparation intended for external use. The active ingredient – naftifine hydrochloride has a wide spectrum of action against fungi cause onychomycosis. The polyethylene glycols are included in the developed dosage form of provide the necessary viscosity of the solution (for accurate application and retention in the field of application). The paper presents the results of a study of the stability of a viscous solution of naftifine hydrochloride with a combination of PEG for external use. Over the entire shelf life, the drug must retain the full its chemical, physical, biopharmaceutical and pharmacological properties.Aim. Determination of stability and expiration date of the shelf life of the developed solution of naftifine hydrochloride for external use, intended for the treatment of mycosis of the nail.Materials and methods. Naftifine hydrochloride solution, «Millipor» filter, UV spectrophotometry, potentiometry pH, capillary viscometry.Results and discussion. In the course of the study, the shelf life of the developed alcohol solution of naftifin hydrochloride with a combination of PEG was experimentally determined. The stability of the dosage form was determined by accelerated aging at a temperature of 40 ± 2 °C, in vivo at a temperature of no higher than 25 °C; and in a refrigerator at a temperature of 8 ± 2 °C. Assessment of the stability of the alcohol solution of naftifine hydrochloride was carried out according to the following indicators: the volume of the contents of the bottle, appearance, pH, quantitative content of the active substance, viscosity.Conclusion. Based on the studies, it is recommended to store the naftifine hydrochloride solution at room temperature not higher than 25 °C, in a dark place. It is also allowed to store the solution of naftifine hydrochloride in a refrigerator at a temperature of 8 ± 2 °C