Perturbative QCD study of BsB_s decays to a pseudoscalar meson and a tensor meson

We study two-body hadronic $B_s\to PT$ decays, with $P (T)$ being a light pseudoscalar (tensor) meson, in the perturbative QCD approach. The CP-averaged branching ratios and the direct CP asymmetries of the $\Delta S=0$ modes are predicted, where $\Delta S$ is the difference between the strange numbers of final and initial states. We also define and calculate experimental observables for the $\Delta S=1$ modes under the $B_s^0-\bar{B}_s^0$ mixing, including CP averaged branching ratios, time-integrated CP asymmetries, and the CP observables $C_{f}$, $D_{f}$ and $S_{f}$. Results are compared to the $B_s\to PV$ ones in the literature, and to the $B\to PT$ ones, which indicate considerable U-spin symmetry breaking. Our work provides theoretical predictions for the $B_s\to PT$ decays for the first time, some of which will be potentially measurable at future experiments.Comment: 6 pages, 1 figur

Treatment of non-tuberculosis mycobacteria skin infections

Non-tuberculosis mycobacteria (NTM) skin infections have become increasingly prevalent in recent years, presenting a unique challenge in clinical management. This review explored the complexities of NTM infections localized to the superficial tissues and provided valuable insights into the optimal therapeutic strategies. The antibiotic selection should base on NTM species and their susceptibility profiles. It is recommended to adopt a comprehensive approach that considers the unique characteristics of superficial tissues to improve treatment effectiveness and reduce the incidence of adverse reactions, infection recurrence, and treatment failure. Infection control measures, patient education, and close monitoring should complement the treatment strategies to achieve favorable outcomes in managing NTM skin infections. Further efforts are warranted to elucidate factors and mechanisms contributing to treatment resistance and relapse. Future research should focus on exploring novel treatment options, innovative drug development/delivery platforms, and precise methodologies for determining therapeutic duration. Longitudinal studies are also needed to assess the long-term safety profiles of the integrated approaches

Design and stiffness analysis of a class of 2-DoF tendon driven parallel kinematics mechanism

2-DoF Rotational mechanism is increasingly utilized in a large range of industrial applications. However, the structures of most of the existing mechanisms are very complex, which is a significant challenge for building them, due to the tight tolerance and assembly difficulties. In this paper, a class of 2-DoF tendon driven parallel kinematics mechanisms (TDPKM) are introduced, which can be structured with low manufacturing and assembly difficulties and is able to actively adjust the system stiffness. Since the unique class of mechanisms is developed, the kinematic model is established to derive the stiffness model, which considers the tendon, structural and central joint stiffness. Finally, a set of experiments of the deviation measurement under different payloads within the workspace are implemented and compared with the theoretical calculations presented in this paper. The overall deviation error between the experimental test and theoretical calculation are between 0.9% and 4.7% in the whole workspace

Inelastic parametric analysis of frequencies and seismic responses of soil-multistorey bidirectional eccentric structure interaction system

This paper presents a parametric study on the lateral-torsional coupling behaviours of soil-multistorey bidirectional eccentric structure interaction system from elastic stage to nonlinear inelastic stage. A simplified bidirectional eccentric multistorey dual lateral load-resisting model for the superstructure is proposed to conduct this parametric study. Incorporating the inter-storey restoring force model of the superstructure, the dynamic motion equations and the dynamic stiffness matrix of the soil-multistorey bidirectional eccentric structure interaction system in different loading stages are derived. Based on these, parametric analyses of frequencies and seismic responses for the soil-three storey structure interaction systems from elastic stage to nonlinear inelastic stage are evaluated. Effects of the uncoupled torsion to lateral frequency ratios (Ω) of the corresponding fixed base system, the stiffness eccentricities and different soil types on the frequencies and seismic responses are investigated. Results show that the soil can significantly reduce the lateral-torsional coupling effect and the structural seismic response of the soil-bidirectional eccentric structure interaction system; a smaller Ω value and larger values of the eccentricities lead to a larger reduction in the lateral-torsional coupling effect of the first order mode in nonlinear inelastic stage; the effects of different foundation conditions on the structural seismic responses are weakened by the development of structural inelastic; after considering the soil-structure interaction, the influences of Ω and eccentricities on the structural seismic responses are changed. A softer soil-structure interaction system has a more weaken lateral-torsional coupling effect, and its vibration modes in nonlinear inelastic stage are changed compared with the system situated on other soils

Prognosis Risk of Urosepsis in Critical Care Medicine: A Prospective Observational Study

This study aimed to investigate the clinical features of urosepsis and to raise awareness of this problem. Of the 112 sepsis patients enrolled, 36 were identified as having urosepsis. The bacteria involved in the infection leading to urosepsis included Escherichia coli, Proteus species, Enterococcus species, Klebsiella species, other Gram-positive cocci, and Pseudomonas aeruginosa. Although the organ/system dysfunction appeared earlier in the urosepsis patients than in the other sepsis patients (4.7 ± 2.4 versus 7.2 ± 4.5 hours, < 0.001), the urosepsis patients presented with a better prognosis and lower 28-day mortality rate than the others (6% versus 37%). In the multivariate analysis, the type of sepsis (urosepsis, OR = 0.019, 95% CI = 0.001, 0.335, = 0.007) and SOFA score (OR = 1.896, 95% CI = 1.012, 3.554, = 0.046) remained significantly associated with the survival. The time of admission to the intensive care unit of 17 patients transferred from the Department of Urinary Surgery was significantly prolonged compared with those transferred from other departments (11.6 ± 7.3 versus 7.2 ± 4.9 hours, < 0.05). In conclusion, urosepsis suggested a better prognosis, but attention needs to be paid in clinical practice, especially in urinary surgery

T-cell lymphoblastic lymphoma presenting with pleural effusion: A case report

AbstractAdult lymphoblastic lymphoma (LBL) is an aggressive form of non-Hodgkin lymphoma occurring in predominantly adolescent and young adult men, accounting for 1% to 2% of all non-Hodgkin's lymphomas. In contrast to B-LBL, T-cell LBL is much more common, accounting for up to 90% of disease in adults. Mediastinal mass, pleural and/or pericardial effusions are the major characteristics of T-LBL. We report an 18-year-old male with a pleural effusion, mediastinal mass, a light pericardial effusion, and a normal hemogram. The cytology of the pleural effusion initially suggested malignancy, but definitive diagnosis was unclear. After a medical thoracoscopy, the partial pleura was picked and immunophenotypic study revealed the following: CD3+, TdT+, CD99+, CD20−. The patient was finally diagnosed with T-LBL and died only 6 months after that. The case highlight the point that medical thoracoscopy is a safe and accurate diagnostic procedure for pleural diseases, and partial pleura biopsy with immunophenotyping was essential for achieving the correct diagnosis of LBL