46,887 research outputs found
A Comprehensive Four-Quark Interpretation of D_s(2317), D_s(2457) and D_s(2632)
The recently observed new member of the charm-strange family D_s(2632) which
has a surprisingly narrow width is challenging our theory. D_s(2317) and
D_s(2457) which were observed earlier have similar behaviors and receive
various theoretical explanations. Some authors use the heavy hadron chiral
effective theory to evaluate heavy-light quark systems and obtain a reasonable
evaluation on the masses of D_s(2317) and D_s(2457). An alternative picture is
to interpret them as four-quark or molecular states. In this work, we are
following the later and propose a unitive description for all the three new
members D_s(2632), D_s(2317) and D_s(2457) and at least, so far our picture is
consistent with the data.Comment: 6 page
GSAE: an autoencoder with embedded gene-set nodes for genomics functional characterization
Bioinformatics tools have been developed to interpret gene expression data at
the gene set level, and these gene set based analyses improve the biologists'
capability to discover functional relevance of their experiment design. While
elucidating gene set individually, inter gene sets association is rarely taken
into consideration. Deep learning, an emerging machine learning technique in
computational biology, can be used to generate an unbiased combination of gene
set, and to determine the biological relevance and analysis consistency of
these combining gene sets by leveraging large genomic data sets. In this study,
we proposed a gene superset autoencoder (GSAE), a multi-layer autoencoder model
with the incorporation of a priori defined gene sets that retain the crucial
biological features in the latent layer. We introduced the concept of the gene
superset, an unbiased combination of gene sets with weights trained by the
autoencoder, where each node in the latent layer is a superset. Trained with
genomic data from TCGA and evaluated with their accompanying clinical
parameters, we showed gene supersets' ability of discriminating tumor subtypes
and their prognostic capability. We further demonstrated the biological
relevance of the top component gene sets in the significant supersets. Using
autoencoder model and gene superset at its latent layer, we demonstrated that
gene supersets retain sufficient biological information with respect to tumor
subtypes and clinical prognostic significance. Superset also provides high
reproducibility on survival analysis and accurate prediction for cancer
subtypes.Comment: Presented in the International Conference on Intelligent Biology and
Medicine (ICIBM 2018) at Los Angeles, CA, USA and published in BMC Systems
Biology 2018, 12(Suppl 8):14
Family, learning environments, learning approaches, and student outcomes in a Malaysian private university
This paper presents the quantitative findings from a mixed methods study of students and faculty at a private medical university in Malaysia. In particular, the relationships among students’ individual characteristics, general self-efficacy, family context, university and classroom learning environments, curriculum, approaches to learning, and measures of students’ academic achievement, self-directed learning readiness and mental health at the student level. Data were collected from 392 students attending a private medical university in Malaysia. The findings from the partial least square path (PLSPATH) suggest that: (a) parental involvement continues to impact and influence student learning process, and related student outcomes, at the university level, and (b) a surface approach to learning is related to poor quality processes and outcomes and a deep approach to learning is related to high quality processes and outcomes
On Kernel Formulas and Dispersionless Hirota Equations
We rederive dispersionless Hirota equations of the dispersionless Toda
hierarchy from the method of kernel formula provided by Carroll and Kodama. We
then apply the method to derive dispersionless Hirota equations of the extended
dispersionless BKP(EdBKP) hierarchy proposed by Takasaki. Moreover, we verify
associativity equations (WDVV equations) in the EdBKP hierarchy from
dispersionless Hirota equations and give a realization of associative algebra
with structure constants expressed in terms of residue formula.Comment: 30 pages, minor corrections, references adde
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