14,716 research outputs found

    An acidic fibroblast growth factor protein generated by alternate splicing acts like an antagonist.

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    Polymerase chain reaction amplification of cDNA for acidic fibroblast growth factor in several lines of cultured human cells revealed two forms of mRNA. The novel smaller mRNA lacks the entire second coding exon of the acidic fibroblast growth factor gene, whereas the previously identified mRNA consists of three coding exons. The truncated variant of acidic fibroblast growth factor (aFGF') is only 60 amino acids long with an apparent molecular mass of 6.7 kD on sodium dodecyl sulfate gels in contrast to 18 kD for the full-length acidic fibroblast growth factor. aFGF' elicits only minimal fibroblast proliferation and antagonizes the effects of acidic fibroblast growth factor when added exogenously to or when coexpressed with aFGF in BALB/c/3T3 fibroblasts. Thus, the truncated variant of acidic fibroblast growth factor may provide fibroblasts with a unique mechanism for endogenous regulation of their responses to acidic fibroblast growth factor

    Convergence to equilibrium for many particle systems

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    The goal of this paper is to give a short review of recent results of the authors concerning classical Hamiltonian many particle systems. We hope that these results support the new possible formulation of Boltzmann's ergodicity hypothesis which sounds as follows. For almost all potentials, the minimal contact with external world, through only one particle of NN, is sufficient for ergodicity. But only if this contact has no memory. Also new results for quantum case are presented

    Supershell structure in trapped dilute Fermi gases

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    We show that a dilute harmonically trapped two-component gas of fermionic atoms with a weak repulsive interaction has a pronounced super-shell structure: the shell fillings due to the spherical harmonic trapping potential are modulated by a beat mode. This changes the ``magic numbers'' occurring between the beat nodes by half a period. The length and amplitude of this beating mode depend on the strength of the interaction. We give a simple interpretation of the beat structure in terms of a semiclassical trace formula for the symmetry breaking U(3) --> SO(3).Comment: 4 pages, 4 figures; In version 2, references added. The semiclassical explanation of super-shell structure is refined. Version 3, as appeared in Phys. Rev.

    Suspended semiconductor nanostructures: physics and technology

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    The current state of research on quantum and ballistic electron transport in semiconductor nanostructures with a two-dimensional electron gas separated from the substrate and nanoelectromechanical systems is reviewed. These nanostructures fabricated using the surface nanomachining technique have certain unexpected features in comparison to their non-suspended counterparts, such as additional mechanical degrees of freedom, enhanced electron-electron interaction and weak heat sink. Moreover, their mechanical functionality can be used as an additional tool for studying the electron transport, complementary to the ordinary electrical measurements. The article includes a comprehensive review of spin-dependent electron transport and multichannel effects in suspended quantum point contacts, ballistic and adiabatic transport in suspended nanostructures, as well as investigations on nanoelectromechanical systems. We aim to provide an overview of the state-of-the-art in suspended semiconductor nanostructures and their applications in nanoelectronics, spintronics and emerging quantum technologies

    Super-shell structure in harmonically trapped fermionic gases and its semi-classical interpretation

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    It was recently shown in self-consistent Hartree-Fock calculations that a harmonically trapped dilute gas of fermionic atoms with a repulsive two-body interaction exhibits a pronounced {\it super-shell} structure: the shell fillings due to the spherical harmonic trapping potential are modulated by a beat mode. This changes the ``magic numbers'' occurring between the beat nodes by half a period. The length and amplitude of the beating mode depends on the strength of the interaction. We give a qualitative interpretation of the beat structure in terms of a semiclassical trace formula that uniformly describes the symmetry breaking U(3) \to SO(3) in a 3D harmonic oscillator potential perturbed by an anharmonic term r4\propto r^4 with arbitrary strength. We show that at low Fermi energies (or particle numbers), the beating gross-shell structure of this system is dominated solely by the two-fold degenerate circular and (diametrically) pendulating orbits.Comment: Final version of procedings for the 'Nilsson conference

    Theory of current-driven motion of Skyrmions and spirals in helical magnets

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    We study theoretically the dynamics of the spin textures, i.e., Skyrmion crystal (SkX) and spiral structure (SS), in two-dimensional helical magnets under external current. By numerically solving the Landau-Lifshitz-Gilbert equation, it is found that (i) the critical current density of the motion is much lower for SkX compared with SS in agreement with the recent experiment, (ii) there is no intrinsic pinning effect for SkX and the deformation of the internal structure of Skyrmion reduces the pinning effect dramatically, (iii) the Bragg intensity of SkX shows strong time-dependence as can be observed by neutron scattering experiment.Comment: 4 pages, 3 figure

    Particle Collisions on Stringy Black Hole Background

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    The collision of two particles in the background of a Sen black hole is studied. With the equations of motion of the particles, the center-of-mass energy is investigated when the collision takes place at the horizon of a Sen black hole. For an extremal Sen black hole, we find that the center-of-mass energy will be arbitrarily high with two conditions: (1) spin a0a\neq 0 and (2) one of the colliding particles has the critical angular momentum lc=2l_{\text{c}}=2. For a nonextremal Sen black hole, we show that, in order to obtain an unlimited center-of-mass energy, one of the colliding particles should have the critical angular momentum lc=2r+/al'_{\text{c}}=2 r_{+}/a (r+r_{+} is the radius of the outer horizon for a nonextremal black hole). However, a particle with the angular momentum l=lcl=l'_{\text{c}} could not approach the black hole from outside of the horizon through free fall, which implies that the collision with arbitrarily high center-of-mass energy could not take place. Thus, there is an upper bound of the center-of-mass energy for the nonextremal black hole. We also obtain the maximal center-of-mass energy for a near-extremal black hole and the result implies that the Planck-scale energy is hard to be approached. Furthermore, we also consider the back-reaction effects. The result shows that, neglecting the gravitational radiation, it has a weak effect on the center-of-mass energy. However, we argue that the maximum allowed center-of-mass energy will be greatly reduced to below the Planck-scale when the gravitational radiation is included.Comment: 17 pages, 4 figures, published versio
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