A study of some constituents in human female saliva

Changes in the concentration of some constituents in women's saliva during the menstrual cycle were studied. Saliva was used because it is easier to collect than other body fluids and is continuously available for analysis. Glucose, the enzyme 17-Acetyl-D-glucosaminidase (NAG) and Calcium which are saliva constituents and belong to three different chemical groups were selected for the study. Several analytical techniques were investigated. The fluorometric assay procedure was found to be the best because of its specificity and sensitivity for the estimation of these constituents. resides the fluorametric method a spectrophotometric method was used in the NAG determination and an atomic absorption method in the calcium estimation. Glucose was estimated by an enzymatic method. This is based on the reaction of glucose with the enzymes glucose oxidase and peroxidase to yield hydrogen peroxide, which in turn oxidises a non-fluorescent substrate, p-hydroxyphenylacetic acid, to a highly fluorescent product. The saliva samples in this determination had to be centrifuged at high speed, heated in a boiling water bath, centrifuged again and then treated with a mixture of cation and anion resins to remove the substances that inhibited the enzyme system. In the determination of the NAG activity the saliva samples were diluted with citric acid/phosphate buffer, and then centrifuged at high speed. The assay was based on the enzymic hydrolysis of the non-fluorescent substrate 4-Methyl-umbelli1eryl-p-D-glucosaminide to the highly fluorescent 4-Methyl-umbelliferone• Calcium was estimated by a fluorometric procedure based upon the measurement of the fluorescence produced by the complex formed between calcein blue and calcium, at pH 9 - 13. From the results obtained from the analysis of saliva samples of several women it was found that glucose showed a significant increase in its level around the expected time of ovulation. This was found in seven cycles out of ten. Similar results were found with the enzyme NAG. No significant change in the calcium levels was observe& at any particular time of the cycle. The levels of the glucose, the activity of the enzyme NAG and the concentration of the calcium were found to change daily, and to differ from one subject to another and in the same subject from cycle to cycle. The increase observed it salivary glucose levels and the enzyme NAG activity could be monitored to predict the time of ovulation

Research in Medical Imaging Using Image Processing Techniques

Medical imaging is the procedure used to attain images of the body parts for medical uses in order to identify or study diseases. There are millions of imaging procedures done every week worldwide. Medical imaging is developing rapidly due to developments in image processing techniques including image recognition, analysis, and enhancement. Image processing increases the percentage and amount of detected tissues. This chapter presents the application of both simple and sophisticated image analysis techniques in the medical imaging field. This chapter also summarizes how to exemplify image interpretation challenges using different image processing algorithms such as k-means, ROI-based segmentation, and watershed techniques

The Role of Magnetic Resonance Imaging (MRI) in Autonomic Nervous System Monitoring

Medical imaging of the nervous system is the methodology used to achieve pictures of parts of the nervous system for therapeutic uses to recognize the ailments. Magnetic resonance imaging (MRI) is a kind of medical imaging tool that utilizes solid magnetic fields and radio waves to deliver point-by-point pictures of the inside of the body. There are large number of imaging methodologies done each week around the world. Medical imaging is developing rapidly due to developments in image acquisition tools including functional MRI and hybrid imaging modalities. This chapter abridged the role of magnetic resonance imaging (MRI) in autonomic nervous system monitoring. This chapter also summarizes the image interpretation challenges in diagnosing autonomic nervous system disorders

Application of Medical Imaging in Diagnosis and Assessment of Myocarditis and Pericarditis

Medical imaging is of one of the most essential means in the investigation of cardiac disorders. In patients, the detection of the whole heart and its adjacent tissues is a crucial procedure since it helps in myocarditis and pericarditis managements. Weekly, there are millions of cardiac imaging performed globally. Medical imaging and processing techniques such as image segmentation, augmentation, and scrutiny can detect cardiac lesions rapidly and precisely. This chapter discusses the application of medical imaging in the diagnosis of myocarditis and pericarditis. This chapter also summarized how to demonstrate image interpretation challenges using diverse image processing procedures and techniques

Fibrewise Near Compact and Locally Near Compact Spaces

In this paper we define and study new concepts of fibrewise topological spaces over B namely, fibrewise near compact and fibrewise locally near compact spaces, which are generalizations of well-known concepts near compact and locally near compact topological spaces. Moreover, we study relationships between fibrewise near compact (resp., fibrewise locally near compact) spaces and some fibrewise near separation axioms. Keywords: Fibrewise topological spaces, Fibrewise near compact spaces, Fibrewise locally near compact spaces, Fibrewise near separation axioms. Math. Subject Classification 2010: Primary 55R70, 55P05, Secondary 54C05, 54C08, 54C10

HIF-1α and ENPP2 as Biomarkers in Chemotherapy Resistance of Children with Neuroblastoma in south Iraq

Background: The most common extra-cranial solid tumor in kids, Neuroblastoma (NB) accounts for 10% of all pediatric oncology fatalities. It emerges in the embryonic neural crest due to the uncontrolled behavior of sympathetic nervous system progenitors, giving rise to heterogeneous tumors. Although immunotherapy and targeted therapy have advanced quickly, surgery, chemotherapy, and radiation (RT) still make up the majority of first-line options for treating cancer. Recurrence of the illness and diminished efficacy of chemotherapy and RT are among the factors that contribute to treatment failure. This study was aimed at evaluating the effects HIF-1α, ENPP2 and oxidant / antioxidant of chemotherapy resistance with NB children.Methods: This study extended from May 2022 to end of March 2023, with age range  2 months to 12 years. 70 children (male/ female) were divided into three groups. Group A: includes 35 healthy children as control group, and  group B: includes 35 patients  of Newly diagnosed   and  group C: after three cycles of chemotherapy. Detailed information regarding the age and gender was recorded for every participant.Results: The present study's findings showed a considerable rise in (p˂0.05) at the levels of HIF-1α, MDA, ENPP2   while the outcomes showed a statistically significant  decrease (p˂0.05) at the levels of GSH,  in the sera samples of patients with NB  (pre-treatment) when compared to the control group. The findings, on the other hand, demonstrate that each of the following parameters—HIF-1, MDA, and GSH—decreased in levels in NB patients after receiving chemotherapy dosages. Nevertheless, following therapy, ENPP2 levels increased.Conclusion: Our findings are indicative of the fact that early diagnosis plays an important role in the effectiveness of chemotherapy. and the levels of oxidant- anti oxidant status, HIF-1α and ENPP2 are significant features of the monitoring of disease progression and the efficacy of treatment

Aesthetics of Space Organization: Lessons From Traditional European Cities

For centuries the aesthetic significance of space organization has been one of the significant subjects of study for most artists, architects, urban designers and philosophers. Cities which experience diverse stages of growth transmit dissimilar aesthetic values due to their locations, culture, history and background. This research will try to take out the aesthetic values of the traditional European cities through the literature on aesthetic of urban design. Accordingly, this study reflects the term urban aesthetics in spatial organization. It tries to answer the question of how space organization can lead to the aesthetic understanding of a place. The methodology for this study developed based on grounded theory study and qualitative assessments of European cities thorough the literature review. Overall, the study assessed integration, visual connectivity, vitality, spatial quality, as the main factors in shaping the aesthetic quality of the urban environment in European traditional cities. At the end, it proposed the findings to apply in contemporary urban designing

The Effects of Surface Roughness on the Squeeze Film Characteristics with Couple stress fluids in Hip joint

On the basis of the Stokes micro continuum theory , This paper aims to study the effects of surface roughness and couple stress on the squeeze film Characteristics in hip joint. The cartilage is modeled as biphasic poro-elastic  matrix and synovial fluid is modeled as couple stress fluid  . Compared to the conventional Newtonian lubricant case, the couple stress and surface roughness effects characterized by the couple stress and surface roughness parameter signify an improvement in the squeeze film Characteristics. Increasing values of the  surface roughness  parameter increases the load-carrying capacity and the squeeze in the squeeze film can be decreased and provides a longer time to prevent sphere –plane surface contact .The approaching time of the sphere in reducing the film thickness h*=1 to h*= 0for the couple stress fluid lubricant which is longer than surface roughness. Keywords: Surface roughness, Couple stress fluid, Articular cartilage, Synovial fluid, Micro continuum theory, Hip joint

Investigación del efecto de la temperatura de recocido sobre las propiedades ópticas de películas delgadas de CdSe

Introduction: CdSe is an important II–VI semiconducting material dueto its typical optical properties such as small direct band gap (1.7 eV) anda high refractive index and, thus, a major concern is focused on the investigation of optical properties of CdSe thin films which is important topromote the performances of the devices of solid -state such as SC (solar cells), thin film transistors, LED (light-emitting diodes), EBPL (electron–beam pumped lasers) and electroluminescent devices. In the presentwork, CdSe thin films were deposited by thermal evaporation method andthe results have been analysed and presented. Materials and Methods:CdSe thin films has been deposited on glass microscopic slides as substrates of (75×25×1 mm) under room temperature using PVD technique.CdSe blended powders gets evaporated and condensed on the substrate.The film thickness (t = 100 5 nm) which is measured using Michelsoninterferometry method. Transmission spectrum, from 200-1100 nm, arescanned using two beams UV–VIS Spectrophotometer (6850 UV/Vis.Spectrophotometer-JENWAY). The deposited films then were annealedat temperature range of (1500C to 3500C) under vacuum to have a stable phase of the material and prevent surface oxidization. Results andDiscussion: A transmittance spectrum of CdSe thin film is scanned overwavelength range 200 to 1100 nm using a (6850 UV/Vis. Spectrophotometer-JENWAY) at room temperature. The transmittance percentagebetween the as-deposited film and the annealed films change varies from(17.0%) to (47.0%). It is clearly seen that there is a shift toward higher energy (Blue Shift) in the transmittance spectrum. As annealing temperatureincreased the transmittance edge is shifted to the longer wavelength (i.e.,after annealing the CdSe films shows red shifts in their optical spectra).The band gap was found within the range 1.966-1.7536 eV for CdSe thinfilm. As annealing temperature increases, the Eg continuously decreases.Conclusions: CdSe thin films have been deposited using Physical VaporDeposition (PVD) Technique. It is found that the transmission for asdeposited films is (17%) and increases to (47%) as annealing temperature increases. Beside this the energy gap for as- deposited CdSe film is(1.966eV) and decreased from (1.909 eV) to (1.7536eV) as the annealingtemperature increases. There is a strong red shift in optical spectrum ofthe annealed CdSe films. There is a gradual shift of the annealed filmsthin film spectra as compared of bulk CdSe film

The hydrodynamic Effect of the Hyaluronic Acid on the Performance Improvement of the Human Synovial Joint

The aim of this article is to present an the theoretical analysis of the problem is presented through a mathematical model  depended on the idea of a Hyaluronic acid (HA) in cartilage  and  synovial fluid surrounding the joints (hip, knee and ankle)  where are a major component of synovial fluid modified  Reynolds equation  governing the fluid film pressure was derived and solved analytically,  and closed form expressions for the squeeze film pressure and load carry capacity were  presented. The influence of film thickness and sliding motion on the squeeze film Characteristics were discussed .It has been found that the effect of  decreased film thickness tend to increased the load carry capacity , friction force and decreased  flow rate, The effect of decreased sliding motion tend to increasing frication force and decreased flow rate and  when additives Hyaluronic acid (HA) to bearing material (articular cartilage ) .The results indicate to  increasing pressure distribution (P) and improve both load carry capacity (W), friction force (F) Compared to the disease synovial hip joint. Keywords: Hyaluronic acid , Hip joint, load carry capacity, friction force.