Human error control in the collaborative workflow modeling tool based on GEMS model

Business process should support the execution of collaboration process with agility and flexibility through the integration of enterprise inner or outer application and human resources from the collaborative workflow view.Although the dependency of enterprise activities to the automated system has been increasing, human role is as important as ever.In the workflow modelling this human role is emphasized and the structure to control human error by analysing decision-making itself is needed.Also, through the collaboration of activities agile and effective communication should be constructed, eventually by the combination and coordination of activities to the aimed process the product quality should be improved.This paper classifies human errors can be occurred in collaborative workflow by applying GEMS(Generic Error Modelling System) to control them, and suggests human error control method through hybrid based modelling as well.On this base collaborative workflow modeling tool is designed and implemented. Using this modelling methodology it is possible to workflow modeling could be supported considering human characteristics has a tendency of human error to be controlled

KINEMATIC ANALYSIS OF GOLF SWING PERFORMED WITH INTENDED LATE HITTING

The purposes of this study were to analyze and compare the kinematic parameters for standard and purpose golf swings. The purpose golf swing is characterized as intended late hitting and increase displacement of ball through the air (carry). Twenty-five male college golfers were recruited as sUbjects and Science eye field 3 camera system was used to measure the parameters of deterministic model. Paired t-test was used to compare between two different golf swings and correlation coefficients between selected parameters and carry were also computed. As results, a significant difference between standard and purpose golf swings was found in terms of increasing carry. Coefficients of correlation indicated that post-impact ball velocity, pre-impact club head velocity, and meet rate were positively correlated with carry. However, backspin, and angle of release were negatively correlated with carry. These results represented that the parameters of deterministic model were very useful indicators to determine performance and the purpose swing is beneficial to increase carry

Characterization of Fabry mice treated with recombinant adeno-associated virus 2/8-mediated gene transfer

<p>Abstract</p> <p>Background</p> <p>Enzyme replacement therapy (ERT) with α-galactosidase A (α-Gal A) is currently the most effective therapeutic strategy for patients with Fabry disease, a lysosomal storage disease. However, ERT has limitations of a short half-life, requirement for frequent administration, and limited efficacy for patients with renal failure. Therefore, we investigated the efficacy of recombinant adeno-associated virus (rAAV) vector-mediated gene therapy for a Fabry disease mouse model and compared it with that of ERT.</p> <p>Methods</p> <p>A pseudotyped rAAV2/8 vector encoding α-Gal A cDNA (rAAV2/8-hAGA) was prepared and injected into 18-week-old male Fabry mice through the tail vein. The α-Gal A expression level and globotriaosylceramide (Gb3) levels in the Fabry mice were examined and compared with Fabry mice with ERT. Immunohistochemical and ultrastructural studies were conducted.</p> <p>Results</p> <p>Treatment of Fabry mice with rAAV2/8-hAGA resulted in the clearance of accumulated Gb3 in tissues such as liver, spleen, kidney, heart, and brain with concomitant elevation of α-Gal A enzyme activity. Enzyme activity was elevated for up to 60 weeks. In addition, expression of the α-Gal A protein was identified in the presence of rAAV2/8-hAGA at 6, 12, and 24 weeks after treatment. α-Gal A activity was significantly higher in the mice treated with rAAV2/8-hAGA than in Fabry mice that received ERT. Along with higher α-Gal A activity in the kidney of the Fabry mice treated with gene therapy, immunohistochemical studies showed more α-Gal A expression in the proximal tubules and glomerulus, and less Gb3 deposition in Fabry mice treated with this gene therapy than in mice given ERT. The α-gal A gene transfer significantly reduced the accumulation of Gb3 in the tubules and podocytes of the kidney. Electron microscopic analysis of the kidneys of Fabry mice also showed that gene therapy was more effective than ERT.</p> <p>Conclusions</p> <p>The rAAV2/8-hAGA mediated α-Gal A gene therapy provided improved efficiency over ERT in the Fabry disease mouse model. Furthermore, rAAV2/8-hAGA-mediated expression showed a greater effect in the kidney than ERT.</p

The Acute and Chronic Effect of Korea Ginseng Supplement on Exercise Performance, Cognitive Function, and Fatigue Recovery

The purpose of this study was to determine the acute and chronic effects of Korean ginseng supplements on exercise performance, cognitive function, and fatigue recovery. The study used double-blind, placebo-controlled, crossover design. Twelve healthy adult males (age = 31 ± 6.86 yrs) were randomly assigned to either KGD or placebo trials. All subjects conducted the exercise consisted with 30 minutes cycling at 70-75% of VO2 max followed by 16 km time trial with 30 minutes resting periods. All subjects were tested for muscular power, strength, endurance, cognitive function, and fatigue. The subjects took KGD (280 ml containing 5.88 mg of ginsenosides) or placebo 90 mins before exercise trials and following 7 days. The blood sample was drawn for IL-6, myoglobin, and total antioxidant capacity immediately after time trial, as well as 2, 24, 48, and 72 hours. After 2 weeks of wash-out period, the subjects were crossed over into the opposite trial and performed the same test. Repeated measures ANOVAs were used to examine the effect of acute and chronic intake of ginseng on exercise performance and blood variables. An alpha of .05 was used, and the Greenhouse-Geisser (G-G) adjusted F and degrees of freedom were reported. In a placebo trial, peak power and mean power levels were significantly decreased across time, F (1.47, 13.24) = 4.63, G-G p = .039, h2p = .340 and F (1.46, 13.13) = 5.31, G-G p = .028, h2p = .371 while no differences were found in a ginseng trial. In a placebo trial, average reaction time (ART) was significantly increased across time, F (1.29, 11.63) = 10.81, G-G p = .005, h2p = .546, but in a ginseng trial, no difference in ART was found across time, F (1.54, 13.86) = 4.02, G-G p = .051, h2p = .309. There was a significant increase in TAC across time in a ginseng trial, F (1.42, 11.37) = 5.07, G-G p = .035, h2p = .388 while no difference was found in a placebo trial. No significant differences were found in other variables from placebo and ginseng trails. The 7 days of KRG supplementation significantly reduced the serum myoglobin concentration across time in the KGD trial, F (1.88, 13.17) = 5.18, G-G p = .023, while no difference was found in the placebo trial, F (2.21, 17.66) = .88, G-G p = .443. No significant differences were observed in serum total antioxidant activity and IL-6 between KGD and placebo trials. The study shows that Korean ginseng supplement before stating the exercise improve anaerobic capacity, cognitive function in particular psychomotor vigilance task, and fatigue recovery during cycling exercise. And 7 days of Korean ginseng supplement reduces muscle damage and fatigue after cycling exercise

Effect of biochars pyrolyzed in N2 and CO2, and feedstock on microbial community in metal(loid)s contaminated soils

Little is known about the effects of applying amendments on soil for immobilizing metal(loid)s on the soil microbial community. Alterations in the microbial community were examined after incubation of treated contaminated soils. One soil was contaminated with Pb and As, a second soil with Cd and Zn. Red pepper stalk (RPS) and biochars produced from RPS in either N2 atmosphere (RPSN) or CO2 atmosphere (RPSC) were applied at a rate of 2.5% to the two soils and incubated for 30 days. Bacterial communities of control and treated soils were characterized by sequencing 16S rRNA genes using the Illumina MiSeq sequencing. In both soils, bacterial richness increased in the amended soils, though somewhat differently between the treatments. Evenness values decreased significantly, and the final overall diversities were reduced. The neutralization of pH, reduced available concentrations of Pb or Cd, and supplementation of available carbon and surface area could be possible factors affecting the community changes. Biochar amendments caused the soil bacterial communities to become more similar than those in the not amended soils. The bacterial community structures at the phylum and genus levels showed that amendment addition might restore the normal bacterial community of soils, and cause soil bacterial communities in contaminated soils to normalize and stabilize

The effect of medically-attended injury experience on the use of home safety equipment

Purpose To assess the effect of medically-attended injury (MAI) on the use of home safety equipment, we analyzed the differences in parents’ perception and attitude about injury prevention, and use of home safety equipment depending on the children’s MAI experiences. Methods From March 2018 through February 2019, we surveyed parents of children aged 5 years or younger via a mobile phone. The parents were divided into the MAI and non-MAI groups. The mobile survey focused on the perception and attitude about injury prevention, and use of home safety equipment (if not used, barriers). Results Of the 204 parents, 75 (36.8%) reported their children’s MAI, comprising the MAI group. This group used the safety equipment more frequently than the non-MAI group (odds ratio, 7.03; 95% confidence interval, 3.39-14.59; P < 0.001). No significant differences between the 2 groups were found in the perception and attitude about injury prevention, barriers to the use of the equipment, and the type of the equipment in use. Conclusion Parents’ experience in their children’s MAIs was associated with the use of home safety equipment, but it did not affect their perception and attitude about injury prevention. A visit to the emergency department with MAI is an opportunity for education on injury prevention and changes of the attitude

The effects of home safety intervention on guardians’ behaviors of injury prevention in injured children: a double blind randomized controlled study

Purpose The optimal time for home safety intervention for children’s injury prevention is during the injury-related visits to emergency departments. The authors investigated the effect of home safety equipment provision on the guardians’ perception of injury prevention and attitude toward it, and the use of home safety equipment. Methods We conducted a double blind randomized controlled study on guardians of children aged 7 years or younger who visited the emergency department with accidental injuries. After completing the structured, pre-intervention survey on home safety, the guardians were randomly assigned to receive either home safety equipment (the intervention group) or stationery (the control group) in the same opaque boxes enclosing pamphlets about home safety education. After 4 weeks, the guardians were contacted for the post-intervention survey. The questionnaires for the latter survey consisted of the same contents with 2 added questions regarding the use of new home safety equipment after intervention. Logistic regressions were conducted to identify factors associated with the outcome (i.e., behavioral change). Results From April through October 2019, we approached 972 guardians. Of these, 59 guardians answered both pre- and post-intervention surveys. No differences were found in the perception and attitude, and use of home safety equipment between the intervention and control groups at the pre- and post-intervention surveys. No variables were associated with the primary outcome. Conclusion Provision of home safety equipment may be inadequate to improve guardians’ behaviors about prevention of domestic injuries