Assembly for Walking Support

Import 05/08/2014Diplomová práce se zabývá návrhem zařízení pro podporu chůze v důlním prostředí. V úvodu provedu seznámení se stavem přepravy osob v dolech v České republice i v zahraničí. Dále popíši různé způsoby dopravy osob v úklonných trasách v podzemí s bližším zaměřením na zařízení podpory chůze. V další části je řešen výpočet dopravního výkonu, obvodové síly na kotouči a potřebného výkonu elektromotoru. Tyto parametry jsou počítány jak dle normy ISO, tak graficko-početní metodou. Následuje návrh poháněcí a vratné stanice, kde zkontroluji hřídel a navrhnu ložiska. Výkresy všech navržených částí jsou doloženy v příloze diplomové práce.This master’s thesis describes the design of device to assembly for walking support in mines. In the introduction is made familiarization with the situation of passenger transport in mines in the Czech Republic and abroad. I’ll also describe various forms of transport on routes in the underground with a closer focus on assembly for walking support. The next part is the calculation of transport performance, circuit forces on the disc and required engine output. These parameters are calculated per ISO and graphical-numerical method. The following is driving and return stations design where I am checking shaft, its connection with wheel and designed bearings. Drawings of the proposed sections are illustrated in Annex thesis.340 - Katedra výrobních strojů a konstruovánívelmi dobř

Additional file 5: Figure S5. of Central peptidergic modulation of peripheral olfactory responses

Hydrophobicity plots for the various NPFR isoforms. Hydrophobicity plots and membrane topology predictions for the NPFR-RD, RA, RB, and RC isoforms. (PDF 1821 kb

Additional file 1: Figure S1. of Central peptidergic modulation of peripheral olfactory responses

NPF expression patterns. A Brains from male flies >10 days post-eclosion stained with an NPF-specific antiserum (green) show clear NPF depletion in NPF-G4 > NPF-IR flies compared to the NPF-GAL4/+ and UAS-NPF-IR/+ heterozygous controls. All brains are counter-stained with the nc82 neuropil marker (magenta). Scale bars, 50 μm. B, C Brains from (2x)NPF-Gal4 > (2x)UAS-myr::GFP flies stained with a GFP-specific antiserum show neuronal processes of NPF neurons innervating the antennal lobes in both males and females (C). (PDF 6184 kb

Additional file 7: of Central peptidergic modulation of peripheral olfactory responses

Data values for Figs. 3c and 6f. (XLSX 11 kb

Additional file 3: Figure S3. of Central peptidergic modulation of peripheral olfactory responses

NPFR loss of function reduces the responses of ab3A neurons to methyl butyrate and apple odor. A Peak odor-evoked activity of ab3A neurons from w 1118 and w 1118 ; NPFR c01896 mutant flies responding to solvent (paraffin oil, PO) or a major apple odor: methyl butyrate (MB, 10−6 v/v, 10−5 v/v, 10−4 v/v). The data in A represent recordings from 7- to 14-day-old flies of both sexes and are presented as means ± 95% confidence intervals. Two-way ANOVA, non-significant (ns), P < 0.01 (**), P < 0.001 (***). Replicate numbers for PO, w 1118  = 12; MB 10−6 v/v, w 1118  = 6; MB 10−5 v/v, w 1118  = 6; MB 10−4 v/v, w 1118  = 6; PO, NPFR c01896  = 12; MB 10−6 v/v, NPFR c01896  = 6; MB 10−5 v/v, NPFR c01896  = 6; MB 10−4 v/v, NPFR c01896  = 6. B Peak odor-evoked activity from ab3A neurons of 7- to 14-day-old flies of both sexes responding to apple skin odor. Boxplot whiskers indicate minimum and maximum values, one-way ANOVA, P < 0.001 (***). Replicate numbers for apple, w 1118  = 6; apple, NPFR c01896  = 7. (PDF 1298 kb

Additional file 5: of ChARM: Discovery of combinatorial chromatin modification patterns in hepatitis B virus X-transformed mouse liver cancer using association rule mining

Functional annotation for the pattern. Table S1. Functional enrichment analysis for the promoter pattern. Table S2. Functional enrichment analysis for the gene body pattern. Table S3. Functional enrichment analysis for differentially expressed genes. (XLS 168 kb

Additional file 1: of ChARM: Discovery of combinatorial chromatin modification patterns in hepatitis B virus X-transformed mouse liver cancer using association rule mining

Association rules. A set of all association rules discovered for promoters and gene bodies present and rules are sorted by lift and support. Table S1. All association rules discovered in promoters. Table S2. All association rules discovered in gene bodies. Table S3. mRNA IDs in P155. Table S4. mRNA IDs in G155. Table S5. Pattern Specification. Table S6. Supersets of G155. Table S7. Filtered rules for P155. Table S8. Filtered rules for G155. (XLSX 310 kb

QTL and fine-scale mapping of female fecundity localizes to 5 positional candidate genes.

<p>(A) QTL scan results for fecundity. The <i>x</i>-axis represents position along the three major <i>D. melanogaster</i> chromosomes in megabases (Mb). Tick marks represent location of polymorphic markers used for QTL mapping and black squares represent the approximate location of the centromeres. The <i>y</i>-axis represents the strength of association between a particular region and fecundity. The horizontal line represents the 95% permutation threshold. (B) Deficiency map of the QTL region on 2R. The <i>x-axis</i> represents position along chromosome 2R in megabases (Mb). Tick marks represent location of known genes and the horizontal bars represent the location (either molecularly defined or approximate) of deficiency break points. Grey bars represent deficiencies that complemented the RIL alleles, black bars represent deficiencies that failed to complement the RIL alleles. The five named genes are those genes identified by quantitative complementation as candidates genes affecting fecundity. (C) Estimated effect of the two RIL alleles at the QTL identified on chromosome 2R. Black and white circles represent high and low fecundity alleles, respectively. The <i>x</i>-axis represents larval rearing condition. The <i>y</i>-axis represents estimated fecundity. Error bars represent 95% CI calculated from amongst line variance. (D–E) Results from quantitative complementation tests with the two deficiencies that failed to complement the two alleles in the mapping population. The <i>x</i>-axis of each inset represents the tester chromosome (either “wild-type”- CyO, or deficiency – Def). Black vs. white circles represent the high and low fecundity RIL alleles, respectively. The <i>y</i>-axis of each inset represents estimated fecundity (see <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002631#s3" target="_blank">Materials and methods</a> for more details). Error bars represent 95% CI based on non-parametric bootstrap resampling (5000 replicates), conditional on fly.</p

Three-Dimensional Microcavity Array Electrodes for High-Capacitance All-Solid-State Flexible Microsupercapacitors

We report novel three-dimensional (3D) microcavity array electrodes for high-capacitance all-solid-state microsupercapactiors. The microcavity arrays are formed in a polymer substrate via a plasma-assisted reactive ion etching (RIE) process and provide extra sidewall surface areas on which the active materials are grown in the form of nanofibers. This 3D structure leads to an increase in the areal capacitance by a factor of 2.56 for a 15-μm-deep cavity etching, agreeing well with the prediction. The fabricated microsupercapactiors exhibit a maximum areal capacitance of 65.1 mF cm^–2 (a volumetric capacitance of 93.0 F cm^–3) and an energy density of 0.011 mWh cm^–2 (a volumetric energy density of 16.4 mWh cm^–3) which substantially surpass previously reported values for all-solid-state flexible microsupercapacitors. The devices show good electrochemical stability under extended voltammetry cycles and bending cycles. It is demonstrated that they can sustain a radio frequency (rf) microsystem in a temporary absence of a power supply. These results suggest the potential utility of our 3D microsupercapactiors as miniaturized power sources in wearable and implantable medical devices

Tissue-specific expression of <i>Drip</i>, <i>Crz</i>, and <i>pale</i> between the different RIL alleles.

<p>The <i>y</i>-axis represents fold change in <i>Drip</i> expression between low- and high-fecundity alleles, normalized to differences in <i>Rpl32</i>. Error bars represent 95% CI based on permutations; see text for details. The horizontal, dashed line represent the null hypothesis of no change in gene expression.</p