5,462 research outputs found
Frequency-Based Decentralized Conservation Voltage Reduction Incorporated Into Voltage-Current Droop Control for an Inverter-Based Islanded Microgrid
Conservation voltage reduction (CVR) aims to decrease load demands by regulating bus voltages at a low level. This paper proposes a new strategy for decentralized CVR (DCVR), incorporated into the current-based droop control of inverter-interfaced distributed energy resources (IDERs), to improve the operational reliability of an islanded microgrid. An controller is developed as an outer feedback controller for each IDER, consisting of controllers for the DCVR and and controllers for power sharing. In particular, the controllers adjust the output voltages of the IDERs in proportion to the frequency variation determined by the controllers. This enables the output voltages to be reduced by the same amount, without communication between the IDERs. The controllers are responsible for reactive power sharing by adjusting the voltages while taking into account the controllers. Small-signal analysis is used to verify the performance of the proposed DCVR with variation in the and droop gains. Case studies are also carried out to demonstrate that the DCVR effectively mitigates an increase in the load demand, improving the operational reliability, under various load conditions determined by power factors and load compositions.11Ysciescopu
Electrogenic transport and K(+) ion channel expression by the human endolymphatic sac epithelium.
The endolymphatic sac (ES) is a cystic organ that is a part of the inner ear and is connected to the cochlea and vestibule. The ES is thought to be involved in inner ear ion homeostasis and fluid volume regulation for the maintenance of hearing and balance function. Many ion channels, transporters, and exchangers have been identified in the ES luminal epithelium, mainly in animal studies, but there has been no functional study investigating ion transport using human ES tissue. We designed the first functional experiments on electrogenic transport in human ES and investigated the contribution of K(+) channels in the electrogenic transport, which has been rarely identified, even in animal studies, using electrophysiological/pharmacological and molecular biological methods. As a result, we identified functional and molecular evidence for the essential participation of K(+) channels in the electrogenic transport of human ES epithelium. The identified K(+) channels involved in the electrogenic transport were KCNN2, KCNJ14, KCNK2, and KCNK6, and the K(+) transports via those channels are thought to play an important role in the maintenance of the unique ionic milieu of the inner ear fluid
Economic and Environmental Impacts of Cellulosic Feedstock Production in Minnesota
Crop Production/Industries, Environmental Economics and Policy, Production Economics,
Epigenetic Regulation of Hepatitis B Virus Replication
Hepatitis B virus (HBV) is the most important cause of chronic viral hepatitis worldwide. The genome of HBV is 3.2 kb partially double-stranded DNA, which is translocated to the nuclei of infected hepatocytes and converted to complete double-stranded DNA, aka covalently closed circular DNA (cccDNA). Typical course of chronic HBV infection results in inactive carrier state with clearance of viral particles in the bloodstream. However, the cccDNA can be detected in the hepatocytes from inactive carriers by sensitive methods. It has been increasingly known that epigenetic mechanisms contribute to the control of HBV replication in the inactive stage of HBV infection. Histone modification and DNA methylation have been identified in the HBV cccDNA, leading to modification of transcriptional activity. The understanding of epigenetic control of transcription will shed light on the development of new therapeutic strategy against HBV cccDNA
Meteorin regulates mesendoderm development by enhancing nodal expression
During gastrulation, distinct lineage specification into three germ layers, the mesoderm, endoderm and ectoderm, occurs through an elaborate harmony between signaling molecules along the embryonic proximo-distal and anterior-posterior axes, and Nodal signaling plays a key role in the early embryonic development governing embryonic axis formation, mesoderm and endoderm specification, and left-right asymmetry determination. However, the mechanism by which Nodal expression is regulated is largely unknown. Here, we show that Meteorin regulates Nodal expression and is required for mesendoderm development. It is highly expressed in the inner cell mass of blastocysts and further in the epiblast and extra-embryonic ectoderm during gastrulation. Genetic ablation of the Meteorin gene resulted in early embryonic lethality, presumably due to impaired lineage allocation and subsequent cell accumulation. Embryoid body culture using Meteorin-null embryonic stem (ES) cells showed reduced Nodal expression and concomitant impairment of mesendoderm specification. Meteorin-null embryos displayed reduced levels of Nodal transcripts before the gastrulation stage, and impaired expression of Goosecoid, a definitive endoderm marker, during gastrulation, while the proximo-distal and anterior-posterior axes and primitive streak formation were preserved. Our results show that Meteorin is a novel regulator of Nodal transcription and is required to maintain sufficient Nodal levels for endoderm formation, thereby providing new insights in the regulation of mesendoderm allocation.open1113sciescopu
Optimal Voltage Control Using an Equivalent Model of a Low-Voltage Network Accommodating Inverter-Interfaced Distributed Generators
The penetration of inverter-based distributed generators (DGs), which can control their reactive power outputs, has increased for low-voltage (LV) systems. The power outputs of DGs affect the voltage and power flow of both LV and medium-voltage (MV) systems that are connected to the LV system. Therefore, the effects of DGs should be considered in the volt/var optimization (VVO) problem of LV and MV systems. However, it is inefficient to utilize a detailed LV system model in the VVO problem because the size of the VVO problem is increased owing to the detailed LV system models. Therefore, in order to formulate and solve the VVO problem in an efficient way, in this paper, a new equivalent model for an LV system including inverter-based DGs is proposed. The proposed model is developed based on an analytical approach rather than a heuristic-fitting one, and it therefore enables the VVO problem to be solved using a deterministic algorithm (e.g., interior point method). In addition, a method to utilize the proposed model for the VVO problem is presented. In the case study, the results verify that the computational burden to solve the VVO problem is significantly reduced without loss of accuracy by the proposed model.11Ysciescopu
Spontaneous emission enhancement in strain-induced WSe2 monolayer based quantum light sources on metallic surfaces
Atomic monolayers of transition metal dichalcogenides represent an emerging
material platform for the implementation of ultra compact quantum light
emitters via strain engineering. In this framework, we discuss experimental
results on creation of strain induced single photon sources using a WSe2
monolayer on a silver substrate, coated with a very thin dielectric layer. We
identify quantum emitters which are formed at various locations in the sample.
The emission is highly linearly polarized, stable in linewidth and decay times
down to 300 ps are observed. We provide numerical calculations of our
monolayer-metal device platform to assess the strength of the radiative decay
rate enhancement by the presence of the plasmonic structure. We believe, that
our results represent a crucial step towards the ultra-compact integration of
high performance single photon sources in nanoplasmonic devices and circuits
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