23 research outputs found
Effect-site concentration of remifentanil for blunting hemodynamic responses to tracheal intubation using light wand during target controlled infusion-total intravenous anesthesia
UKIRT Widefield Infrared Survey for Fe+
The United Kingdom Infrared Telescope (UKIRT)Widefield Infrared Survey for Fe+ (UWIFE) is a 180 deg2 imaging survey of the first Galactic quadrant (7° < l < 62° |b| <1°.5) that uses a narrow-band filter centred on the [Fe II] 1.644-μm emission line. The [Fe II] 1.644-μm emission is a good tracer of dense, shock-excited gas, and the survey will probe violent environments around stars: star-forming regions, evolved stars, and supernova remnants, among others. The UWIFE survey is designed to complement the existing UKIRTW idefield Infrared Survey for H2 (UWISH2). The survey will also complement existing broad-band surveys. The observed images have a nominal 5Ï? detection limit of 18.7 mag for point sources, with a median seeing of 0.83 arcsec. For extended sources, we estimate a surface brightness limit of 8.1 Ã? 10-20 W m-2 arcsec-2. In this paper, we present an overview and some preliminary results of this survey. © 2014 The Authors Published by Oxford University Press on behalf of the Royal Astronomical Society
Short- and Long-Term Results of Triple Valve Surgery: A Single Center Experience
Triple valve surgery is usually complex and carries a reported operative mortality of 13% and 10-yr survival of 61%. We examined surgical results based on our hospital's experience. A total of 160 consecutive patients underwent triple valve surgery from 1990 to 2006. The most common aortic and mitral valve disease was rheumatic disease (82%). The most common tricuspid valve disease was functional regurgitation (80%). Seventy-four percent of the patients were in New York Heart Association (NYHA) class III and IV. Univariate and multivariable analyses were performed to identify predictors of early and late survival. Operative mortality was 6.9% (n=11). Univariate factors associated with mortality included old age, preoperative renal failure, postoperative renal failure, pulmonary complications, and stroke. Of them, postoperative renal failure and stroke were associated with mortality on multivariable analysis. Otherwise, neither tricuspid valve replacement nor reoperation were statistically associated with late mortality. Survival at 5 and 10 yr was 87% and 84%, respectively. Ninety-two percent of the patients were in NYHA class I and II at their most recent follow-up. Ten-year freedom from prosthetic valve endocarditis was 97%; from anticoagulation-related hemorrhage, 82%; from thromboembolism, 89%; and from reoperation, 84%. Postoperative renal failure and stroke were significantly related with operative mortality. Triple valve surgery, regardless of reoperation and tricuspid valve replacement, results in acceptable long-term survival
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Increased Expression of Herpes Virus-Encoded hsv1-miR-H18 and hsv2-miR-H9-5p in Cancer-Containing Prostate Tissue Compared to That in Benign Prostate Hyperplasia Tissue
Purpose: Previously, we reported the presence of virus-encoded microRNAs (miRNAs) in the urine of prostate cancer (CaP) patients. In this study, we investigated the expression of two herpes virus-encoded miRNAs in prostate tissue. Methods: A total of 175 tissue samples from noncancerous benign prostatic hyperplasia (BPH), 248 tissue samples from patients with CaP and BPH, and 50 samples from noncancerous surrounding tissues from these same patients were analyzed for the expression of two herpes virus-encoded miRNAs by real-time polymerase chain reaction (PCR) and immunocytochemistry using nanoparticles as molecular beacons. Results: Real-time reverse transcription-PCR results revealed significantly higher expression of hsv1-miR-H18 and hsv2-miRH9- 5p in surrounding noncancerous and CaP tissues than that in BPH tissue (each comparison, P<0.001). Of note, these miRNA were expressed equivalently in the CaP tissues and surrounding noncancerous tissues. Moreover, immunocytochemistry clearly demonstrated a significant enrichment of both hsv1-miR-H18 and hsv2-miR-H9 beacon-labeled cells in CaP and surrounding noncancerous tissue compared to that in BPH tissue (each comparison, P<0.05 for hsv1-miR-H18 and hsv2- miR-H9). Conclusions: These results suggest that increased expression of hsv1-miR-H18 and hsv2-miR-H95p might be associated with tumorigenesis in the prostate. Further studies will be required to elucidate the role of these miRNAs with respect to CaP and herpes viral infections
Impact of SO2 on Alteration of Reservoir Rock with Ca-Deficient Conditions and Poor Buffering Capacity under a CO2 Geologic Storage Condition
The objective of this study is to evaluate the impact of SO2-CO2-water-rock interaction on the alteration of a reservoir rock having Ca-deficient conditions and little buffering capacity and its implication for porosity change near the injection well from a CO2 storage pilot site, Republic of Korea. For our study, three cases of experimental and geochemical modeling were carried out (pure CO2, 0.1% SO2 in CO2, and 1% SO2 in CO2, resp.) under realistic geologic storage conditions. Our results show that SO2 accelerated water-rock interactions by lowering the pH. In the 1% SO2 case, pH remained less than 2 during the experiments because of insufficient buffering capacity. Sulfate minerals were not precipitated because of an insufficient supply of Ca. Because the total volume of precipitated secondary minerals was less than that of the dissolved primary minerals, the porosity of rock increased in all cases. Chlorite largely contributed to the decrease in total rock volume although it formed only 4.8 wt.% of the rock. Our study shows that the coinjection of a certain amount of SO2 at CO2 storage reservoirs without carbonate and Ca-rich minerals can significantly increase the porosity by enhancing water-rock interactions. This procedure can be beneficial to CO2 injection under some conditions
Directional Hydraulic Characteristics of Reservoir Rocks for CO2 Geological Storage in the Pohang Basin, Southeast Korea
This study conducted core sampling of an offshore borehole for geological reservoir characterization of a potential CO2 storage site in southeast Korea. From this, two promising geological formations at ~739 and ~779 m were identified as prospective CO2 storage reservoirs. Injection efficiency and CO2 migration were evaluated based on directional measurements of permeabilities from core plugs. The directional transport properties were determined using both a portable probe permeameter and a pressure cell capable of applying different in situ confining pressures. Both steady state and unsteady state measurements were used to determine permeability—the method selected according to the expected permeability range of the specific sample. This expected range was based on rapid screening measurements acquired using a portable probe permeameter (PPP). Anticipated performance of the prototypical CO2 injection site was evaluated based on flow modeling of the CO2 plume migration pathway including CO2 transport through the overlying formations based on the measured directional hydraulic properties. These analyses revealed that the injection efficiency at a depth of 739 m was double that at 779 m. These correlations among and distributions of the directional permeabilities of the potential CO2 geological storage site can be utilized for the assessment of CO2 storage capacity, injectivity, and leakage risk