816 research outputs found
Tumbling into a Crisis: Use of Corporate Apologia after USA Gymnastics Falls off the Balance Beam
In an open letter to U.S. gymnasts on Nov. 5, 2018, United States Olympic Committee (USOC) CEO Sarah Hirshland told its more than 150,000 members “You deserve better” as it launched the Nuclear Clause that would revoke USA Gymnastics (USAG) as a governing body for the sport at the Olympic level [1]. This announcement comes in the wake of USAG’s ongoing crisis that includes a failure to protect athletes from team doctor Larry Nassar, imprisoned for sexually abusing more than 350 female gymnasts; investigations tied to Michigan State University; and the turnover of several USAG CEO’s in just two years. The research question addressed in this study asks how gymnastics can recover from a crisis that was decades in the making and two years in the public spotlight. Benoit’s (1997) Image Repair theory as well as Hearit and Courtright’s (2004) social constructionist approach and apologia discourse inform our critical analysis on how and why USAG has tumbled
Fiduciary Or Force In The 21st Century?
The rise of China over the past three decades is more than astonishing. Some have considered it to be nothing short of an economic miracle. China has transformed itself from a rural backward economy in 1978 to a thoroughly modern-looking economy and society today. While it took the United States almost 50 years (from 1839-86) to double its per capita GDP, China has done it twice in less than twenty years –from 1978-87 and again from 1987-96. The Chinese economy has improved at such a dramatic rate that many commentators have presumed China’s imminent global economic dominance in the 21st century. Many now consider geopolitics a bi-polar affair, where only America and China matter. In 2008, for the first time, serious cracks are beginning to surface in the foundations of China’s economy, prompting a reconsideration of whether China’s future success is as guaranteed and inevitable as first thought. China is facing its most difficult year in this new century. With millions of unemployed workers and a slowing economic growth, China is facing tens of thousands of protests each year. Since the legitimacy of the Chinese government is based on its economic success, China’s continued success in the 21st century will depend on whether the Communist Party is able to maintain trust in its economy, political system and society. China’s economic sustainability rests on whether it can cope successfully with its new- found economic power. The question that has yet to be decided is whether China will adopt a type of fiduciary culture like the ones prevalent in common law countries, such as the U.S. and Britain and its former colony Hong Kong, or will China resort to the use of force to maintain its political and economic power
Racial Norming in the National Football League’s Concussion Settlement: A Nested Approach to Addressing an Ongoing Crisis
For more than two decades, the National Football League (NFL) has been in the spotlight over the concussion crisis, resulting in a lawsuit by 5,000 NFL players and a subsequent 2013 settlement of more than $765 million. In 2020, a new crisis emerged out of the settlement, one of perceived inequities in criteria used to allocate settlement funds. The practice of racial norming, adjusting test scores for race, created another headache for the NFL during a time in which racial injustices in the U.S. spawned public and media discourse. Our case study explores this crisis through the Nested Theory of Conflict to illustrate how conflicts may arise from numerous sources and be intertwined, or nested within one another, and offers a nested model of crises lens from which this case and other crises can be explored
Myoclonus in adult Huntington's disease
Two brothers with clinically definite adult Huntington's disease developed disabling myoclonus years after the first signs of the disease. Their electroencephalograms were consistent with a primary generalized epilipsy, although neither man had seizures. The myoclonus was controlled with valproic acid therapy.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/50341/1/410290217_ftp.pd
Technical Assessment of the National Full Scale Aerodynamic Complex Fan Blades Repair
This report describes the principal activities of a technical review team formed to address National Full Scale Aerodynamic Complex (NFAC) blade repair problems. In particular, the problem of lack of good adhesive bonding of the composite overwrap to the Hyduliginum wood blade material was studied extensively. Description of action plans and technical elements of the plans are provided. Results of experiments designed to optimize the bonding process and bonding strengths obtained on a full scale blade using a two-step cure process with adhesive primers are presented. Consensus recommendations developed by the review team in conjunction with the NASA Ames Fan Blade Repair Project Team are provided along with lessons learned on this program. Implementation of recommendations resulted in achieving good adhesive bonds between the composite materials and wooden blades, thereby providing assurance that the repaired fan blades will meet or exceed operational life requirements
Enhancing Timeliness of Drug Overdose Mortality Surveillance: A Machine Learning Approach
BACKGROUND: Timely data is key to effective public health responses to epidemics. Drug overdose deaths are identified in surveillance systems through ICD-10 codes present on death certificates. ICD-10 coding takes time, but free-text information is available on death certificates prior to ICD-10 coding. The objective of this study was to develop a machine learning method to classify free-text death certificates as drug overdoses to provide faster drug overdose mortality surveillance.
METHODS: Using 2017–2018 Kentucky death certificate data, free-text fields were tokenized and features were created from these tokens using natural language processing (NLP). Word, bigram, and trigram features were created as well as features indicating the part-of-speech of each word. These features were then used to train machine learning classifiers on 2017 data. The resulting models were tested on 2018 Kentucky data and compared to a simple rule-based classification approach. Documented code for this method is available for reuse and extensions: https://github.com/pjward5656/dcnlp.
RESULTS: The top scoring machine learning model achieved 0.96 positive predictive value (PPV) and 0.98 sensitivity for an F-score of 0.97 in identification of fatal drug overdoses on test data. This machine learning model achieved significantly higher performance for sensitivity (p \u3c 0.001) than the rule-based approach. Additional feature engineering may improve the model’s prediction. This model can be deployed on death certificates as soon as the free-text is available, eliminating the time needed to code the death certificates.
CONCLUSION: Machine learning using natural language processing is a relatively new approach in the context of surveillance of health conditions. This method presents an accessible application of machine learning that improves the timeliness of drug overdose mortality surveillance. As such, it can be employed to inform public health responses to the drug overdose epidemic in near-real time as opposed to several weeks following events
Whole-Genome Sequencing and Concordance Between Antimicrobial Susceptibility Genotypes and Phenotypes of Bacterial Isolates Associated with Bovine Respiratory Disease.
Extended laboratory culture and antimicrobial susceptibility testing timelines hinder rapid species identification and susceptibility profiling of bacterial pathogens associated with bovine respiratory disease, the most prevalent cause of cattle mortality in the United States. Whole-genome sequencing offers a culture-independent alternative to current bacterial identification methods, but requires a library of bacterial reference genomes for comparison. To contribute new bacterial genome assemblies and evaluate genetic diversity and variation in antimicrobial resistance genotypes, whole-genome sequencing was performed on bovine respiratory disease-associated bacterial isolates (Histophilus somni, Mycoplasma bovis, Mannheimia haemolytica, and Pasteurella multocida) from dairy and beef cattle. One hundred genomically distinct assemblies were added to the NCBI database, doubling the available genomic sequences for these four species. Computer-based methods identified 11 predicted antimicrobial resistance genes in three species, with none being detected in M. bovis While computer-based analysis can identify antibiotic resistance genes within whole-genome sequences (genotype), it may not predict the actual antimicrobial resistance observed in a living organism (phenotype). Antimicrobial susceptibility testing on 64 H. somni, M. haemolytica, and P. multocida isolates had an overall concordance rate between genotype and phenotypic resistance to the associated class of antimicrobials of 72.7% (P < 0.001), showing substantial discordance. Concordance rates varied greatly among different antimicrobial, antibiotic resistance gene, and bacterial species combinations. This suggests that antimicrobial susceptibility phenotypes are needed to complement genomically predicted antibiotic resistance gene genotypes to better understand how the presence of antibiotic resistance genes within a given bacterial species could potentially impact optimal bovine respiratory disease treatment and morbidity/mortality outcomes
HOXA3 Modulates Injury-Induced Mobilization and Recruitment of Bone Marrow-Derived Cells
The regulated recruitment and differentiation of multipotent bone marrow-derived cells (BMDCs) to sites of injury are critical for efficient wound healing. Previously we demonstrated that sustained expression of HOXA3 both accelerated wound healing and promoted angiogenesis in diabetic mice. In this study, we have used green fluorescent protein-positive bone marrow chimeras to investigate the effect of HOXA3 expression on recruitment of BMDCs to wounds. We hypothesized that the enhanced neovascularization induced by HOXA3 is due to enhanced mobilization, recruitment, and/or differentiation of BMDCs. Here we show that diabetic mice treated with HOXA3 displayed a significant increase in both mobilization and recruitment of endothelial progenitor cells compared with control mice. Importantly, we also found that HOXA3-treated mice had significantly fewer inflammatory cells recruited to the wound compared with control mice. Microarray analyses of HOXA3-treated wounds revealed that indeed HOXA3 locally increased expression of genes that selectively promote stem/progenitor cell mobilization and recruitment while also suppressing expression of numerous members of the proinflammatory nuclear factor κB pathway, including myeloid differentiation primary response gene 88 and toll-interacting protein. Thus HOXA3 accelerates wound repair by mobilizing endothelial progenitor cells and attenuating the excessive inflammatory response of chronic wounds
DECOUPLED PAYMENTS IN A CHANGING POLICY SETTING
The studies in this report analyze the effects of decoupled payments in the Federal Agriculture Improvement and Reform (FAIR) Act on recipient households, and assess land, labor, risk management, and capital market conditions that can lead to links between decoupled payments and production choices. Each study contributes a different perspective to understanding the response of U.S. farm households and production to decoupled income transfers. Some use new microdata on farm households collected through USDA's Agricultural Resource Management Survey (ARMS), initiated in 1996, and its predecessor survey. These data are used to compare household and producer behavior and outcomes before and after the FAIR Act. Other studies use applied or conceptual models to characterize the impact of introducing decoupled payments. Collectively, the chapters represent an early stage in the empirical analysis of decoupled payments. The studies address many aspects of the payments' household impacts but remaining issues call for additional analysis. As the analytical paradigm changes with the evolution of farm programs, the development of appropriate data and models will improve our understanding of farm program impacts on the behavior and well-being of U.S. farm households, and the agricultural sector.Agricultural and Food Policy,
SOFIA/FORCAST and Spitzer/IRAC Imaging of the Ultra Compact H II Region W3(OH) and Associated Protostars in W3
We present infrared observations of the ultra-compact H II region W3(OH) made
by the FORCAST instrument aboard SOFIA and by Spitzer/IRAC. We contribute new
wavelength data to the spectral energy distribution, which constrains the
optical depth, grain size distribution, and temperature gradient of the dusty
shell surrounding the H II region. We model the dust component as a spherical
shell containing an inner cavity with radius ~ 600 AU, irradiated by a central
star of type O9 and temperature ~ 31,000 K. The total luminosity of this system
is 71,000 L_solar. An observed excess of 2.2 - 4.5 microns emission in the SED
can be explained by our viewing a cavity opening or clumpiness in the shell
structure whereby radiation from the warm interior of the shell can escape. We
claim to detect the nearby water maser source W3 (H2O) at 31.4 and 37.1 microns
using beam deconvolution of the FORCAST images. We constrain the flux densities
of this object at 19.7 - 37.1 microns. Additionally, we present in situ
observations of four young stellar and protostellar objects in the SOFIA field,
presumably associated with the W3 molecular cloud. Results from the model SED
fitting tool of Robitaille et al. (2006, 2007} suggest that two objects (2MASS
J02270352+6152357 and 2MASS J02270824+6152281) are intermediate-luminosity (~
236 - 432 L_solar) protostars; one object (2MASS J02270887+6152344) is either a
high-mass protostar with luminosity 3000 L_solar or a less massive young star
with a substantial circumstellar disk but depleted envelope; and one object
(2MASS J02270743+6152281) is an intermediate-luminosity (~ 768 L_solar)
protostar nearing the end of its envelope accretion phase or a young star
surrounded by a circumstellar disk with no appreciable circumstellar envelope.Comment: 12 pages, 8 figures, 2 tables, accepted by Ap
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