2,678 research outputs found
Exploring American Indian Studentsâ Problem-Solving Propensity in the Context of Culturally Relevant STEM Topics
This study presents an out-of-school problem-solving lesson we designed for American Indian students using a culturally relevant STEM topic. The lesson was titled âShelter Design for Severe Weather Conditions.â This shelter design lesson was developed based on an engineering design allowing us to integrate STEM topics within a traditional indigenous house-building context. This problem context was used to encourage students to apply their prior knowledge, experience, and community/cultural practice to solve problems. We implemented the lesson at a summer program on an American Indian reservation. Using the lesson, this study explores how American Indian students use cultural knowledge and experience to solve a STEM problem. We collected student data through pre- and post-STEM content knowledge tests, drawings and explanations of shelter models on the studentsâ group worksheets, and classroom observations. We used interpretive and inductive methods to analyze the data. This study demonstrates that our culturally relevant, STEM problem-solving lesson helped the American Indian students solve a complex, real-world problem. This study examines how studentsâ prior experiences and cultural knowledge affect their problem-solving strategies. Our findings have implications for further research on designing problem-solving lessons with culturally relevant STEM topics for students from historically marginalized populations
MULTI-K: accurate classification of microarray subtypes using ensemble k-means clustering
<p>Abstract</p> <p>Background</p> <p>Uncovering subtypes of disease from microarray samples has important clinical implications such as survival time and sensitivity of individual patients to specific therapies. Unsupervised clustering methods have been used to classify this type of data. However, most existing methods focus on clusters with compact shapes and do not reflect the geometric complexity of the high dimensional microarray clusters, which limits their performance.</p> <p>Results</p> <p>We present a cluster-number-based ensemble clustering algorithm, called <it>MULTI-K</it>, for microarray sample classification, which demonstrates remarkable accuracy. The method amalgamates multiple <it>k</it>-means runs by varying the number of clusters and identifies clusters that manifest the most robust co-memberships of elements. In addition to the original algorithm, we newly devised the <it>entropy-plot </it>to control the separation of singletons or small clusters. MULTI-K, unlike the simple <it>k</it>-means or other widely used methods, was able to capture clusters with complex and high-dimensional structures accurately. MULTI-K outperformed other methods including a recently developed ensemble clustering algorithm in tests with five simulated and eight real gene-expression data sets.</p> <p>Conclusion</p> <p>The geometric complexity of clusters should be taken into account for accurate classification of microarray data, and ensemble clustering applied to the number of clusters tackles the problem very well. The C++ code and the data sets tested are available from the authors.</p
Characteristic Analysis of the Built Environment of Ferry Terminals: A Case Study of Mokpo, South Korea
Ferry terminals are an essential facility for those frequently commuting between islands or towns ashore. Therefore, it is crucial to ensure a smooth and efficient flow of passengers and vehicles while guaranteeing safety and convenience at the ferry terminal. This study investigates and evaluates the walking path environment and determines the passengersâ walkability and walking satisfaction of ferry terminals in Korea. As a case study, to measure the passengerâs overall perception and satisfaction of the built environment of the ferry terminal, we conducted an importanceâperformance analysis for two ferry terminals located in Mokpo city of Korea. The segments of the poor built environment in terms of walking were found. Furthermore, the ANOVA and t-test results confirmed that the satisfaction level of the built environment varied by age and residential location of passengers. There was a significant difference in satisfaction between the groups (age and residential location) in the walking path segments while embarking and disembarking the ferry. Passengersâ perceptions and walking satisfaction were different depending on the features of the built environment, including public transport accessibility, layout, distance, and surface condition of the walking path of the ferry terminal. As a limitation of the study, the case study was conducted only in the Mokpo region due to the impact of COVID-19, and the sample survey was also conducted in a short period of time. In addition, further studies are needed on the generalization of passengersâ walkability in ferry terminals
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High-Performance PVC Gel for Adaptive Micro-Lenses with Variable Focal Length.
This paper presents a bio-inspired adaptive micro-lens with electrically tunable focus made of non-ionic high-molecular-weight polyvinyl chloride (PVC) gel. The optical device mimics the design of the crystalline lens and ciliary muscle of the human eye. It consists of a plano-convex PVC gel micro-lens on Indium Tin Oxide (ITO) glass, confined with an annular electrode operating as an artificial ciliary muscle. Upon electrical activation, the electroactive adhesive force of the PVC gel is exerted on the annular anode electrode, which reduces the sagittal height of the plano-convex PVC gel lens, resulting in focal length variation of the micro-lens. The focal length increases from 3.8âmm to 22.3âmm as the applied field is varied from 200âV/mm to 800âV/mm, comparable to that of the human lens. The device combines excellent optical characteristics with structural simplicity, fast response speed, silent operation, and low power consumption. The results show the PVC gel micro-lens is expected to open up new perspectives on practical tunable optics
Tension pneumopericardium after removal of pericardiocentesis drainage catheter
This image showed tension pneumopericardium caused by removing the pericardiocentesis
catheter, which was inserted to drain malignant pericardial effusion. Tension pneumopericardium
is a rare and potentially fatal event. Mortality from tension pneumopericardium can be
as high as 50%. Therefore, it is important to suspect and detect early, if the patient complained
of dyspnea after removing the pericardiocentesis drainage cathete
The appropriateness of single page of activation of the cardiac catheterization laboratory by emergency physician for patients with suspected ST-segment elevation myocardial infarction: a cohort study
<p>Abstract</p> <p>Background</p> <p>The early use of reperfusion therapy has a significant effect on the prognosis of patients with ST-segment elevation myocardial infarction (STEMI), and it is recommended that emergency department (ED) physicians activate the cardiac catheterization laboratory (CCL) as soon as possible to treat these patients. The aim of this study was to examine the appropriateness of emergency physician activation of the CCL for patients with suspected STEMI. Inappropriate activations (i.e., false positive activations) were identified according to a variety of criteria.</p> <p>Methods</p> <p>All patients with emergency physician CCL activations between August 2009 and April 2011 were included in the study. False positive cases were defined according to ECG criteria and cardiologists' reviews of patients' initial clinical information.</p> <p>Results</p> <p>ED physicians used a STEMI page to activate the CCL 117 times. According to reviews by cardiologists, this activation was appropriate 89.8% of the time (in 105/117 cases). Truly unnecessary activation (i.e., cases in which STEMI was not identified by the cardiologists, no clear culprit coronary artery was present, no significant coronary artery disease and cardiac biomarkers were negative) occurred 5.1% of the time (in 6/117 cases).</p> <p>Conclusions</p> <p>CCL activation was appropriate for most patients and was unnecessary in a relatively small percentage of cases. This result supports the current recommendation for CCL activation by emergency physicians. Such early activation is a key strategy in the reduction of door-to-balloon time.</p
Effects of a radiation dose reduction strategy for computed tomography in severely injured trauma patients in the emergency department: an observational study
<p>Abstract</p> <p>Background</p> <p>Severely injured trauma patients are exposed to clinically significant radiation doses from computed tomography (CT) imaging in the emergency department. Moreover, this radiation exposure is associated with an increased risk of cancer. The purpose of this study was to determine some effects of a radiation dose reduction strategy for CT in severely injured trauma patients in the emergency department.</p> <p>Methods</p> <p>We implemented the radiation dose reduction strategy in May 2009. A prospective observational study design was used to collect data from patients who met the inclusion criteria during this one year study (intervention group) from May 2009 to April 2010. The prospective data were compared with data collected retrospectively for one year prior to the implementation of the radiation dose reduction strategy (control group). By comparison of the cumulative effective dose and the number of CT examinations in the two groups, we evaluated effects of a radiation dose reduction strategy. All the patients met the institutional adult trauma team activation criteria. The radiation doses calculated by the CT scanner were converted to effective doses by multiplication by a conversion coefficient.</p> <p>Results</p> <p>A total of 118 patients were included in this study. Among them, 33 were admitted before May 2009 (control group), and 85 were admitted after May 2009 (intervention group). There were no significant differences between the two groups regarding baseline characteristics, such as injury severity and mortality. Additionally, there was no difference between the two groups in the mean number of total CT examinations per patient (4.8 vs. 4.5, respectively; p = 0.227). However, the mean effective dose of the total CT examinations per patient significantly decreased from 78.71 mSv to 29.50 mSv (p < 0.001).</p> <p>Conclusions</p> <p>The radiation dose reduction strategy for CT in severely injured trauma patients effectively decreased the cumulative effective dose of the total CT examinations in the emergency department. But not effectively decreased the number of CT examinations.</p
Prenatal and early childhood phthalate exposures and thyroid function among school-age children
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