5 research outputs found

    Handling Detector Characterization Data (Metadata) in XENONnT

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    Effective metadata management is a consistent challenge faced by many scientific experiments. These challenges are magnified by the evolving needs of the experiment, the intricacies of seamlessly integrating a new system with existing analytical frameworks, and the crucial mandate to maintain database integrity. In this work we present the various challenges faced by experiments that produce a large amount of metadata and describe the solution used by the XENON experiment for metadata management

    Toward neuroprosthetic real-time communication from in silico to biological neuronal network via patterned optogenetic stimulation

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    Restoration of the communication between brain circuitry is a crucial step in the recovery of brain damage induced by traumatic injuries or neurological insults. In this work we present a study of real-time unidirectional communication between a spiking neuronal network (SNN) implemented on digital platform and an in-vitro biological neuronal network (BNN), generating similar spontaneous patterns of activity both spatial and temporal. The communication between the networks was established using patterned optogenetic stimulation via a modified digital light projector (DLP) receiving real-time input dictated by the spiking neurons' state. Each stimulation consisted of a binary image composed of 8 * 8 squares, representing the state of 64 excitatory neurons. The spontaneous and evoked activity of the biological neuronal network was recorded using a multi-electrode array in conjunction with calcium imaging. The image was projected in a sub-portion of the cultured network covered by a subset of the all electrodes. The unidirectional information transmission (SNN to BNN) is estimated using the similarity matrix of the input stimuli and output firing. Information transmission was studied in relation to the distribution of stimulus frequency and stimulus intensity, both regulated by the spontaneous dynamics of the SNN, and to the entrainment of the biological networks. We demonstrate that high information transfer from SNN to BNN is possible and identify a set of conditions under which such transfer can occur, namely when the spiking network synchronizations drive the biological synchronizations (entrainment) and in a linear regime response to the stimuli. This research provides further evidence of possible application of miniaturized SNN in future neuro-prosthetic devices for local replacement of injured micro-circuitries capable to communicate within larger brain networks.The presented research results have received funding from the European Union’s Seventh Framework Programme (ICT-FET FP7/2007-2013, FET Young Explorers scheme) under grant agreement n284772 BRAINBOW (www.brainbowproject.eu). This work has been realized within the activity of the Joint Italian-Israeli Laboratory on Integrative Network Neuroscience financed by the Italian Ministry of Foreign Affairs (P.B., A.B.). The authors acknowledge financial support from from Ikerbasque (The Basque Foundation for Science) (P.B.) and from the Ministerio Economia, Industria y Competitividad of Spain (grant SAF2015-69484-R (MINECO/FEDER)) (PB). We would like acknowledge the late Prof. Eshel Ben-Jacob whose pioneering research inspired the current study

    AxFoundation/strax: v1.5.4

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    What's Changed Split compare_metadata into utils.compare_meta by @dachengx in https://github.com/AxFoundation/strax/pull/754 Change endtime - time >= 0 to endtime >= time by @JYangQi00 in https://github.com/AxFoundation/strax/pull/756 Mandatorily wrap _read_chunk in a check_chunk_n decorator by @dachengx in https://github.com/AxFoundation/strax/pull/758 New Contributors @JYangQi00 made their first contribution in https://github.com/AxFoundation/strax/pull/756 Full Changelog: https://github.com/AxFoundation/strax/compare/v1.5.3...v1.5.

    AxFoundation/strax: v1.5.5

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    <h2>What's Changed</h2> <ul> <li>Update readthedocs configuration by @dachengx in https://github.com/AxFoundation/strax/pull/763</li> <li>Proposal to use pre-commit for continuous integration by @dachengx in https://github.com/AxFoundation/strax/pull/762</li> <li>Update authorship and copyright info by @JelleAalbers in https://github.com/AxFoundation/strax/pull/771</li> <li>Guard hitlet entropy test from numerical errors by @JelleAalbers in https://github.com/AxFoundation/strax/pull/772</li> <li>Deregister partially replaced multi-output plugins by @JelleAalbers in https://github.com/AxFoundation/strax/pull/775</li> <li>Fix caching issue by @WenzDaniel in https://github.com/AxFoundation/strax/pull/768</li> <li>Add chunk yielding plugin and tests by @WenzDaniel in https://github.com/AxFoundation/strax/pull/769</li> <li>Avoid deprecated generated_jit by @JelleAalbers in https://github.com/AxFoundation/strax/pull/784</li> <li>Also copy dps and remove redundant checks. by @WenzDaniel in https://github.com/AxFoundation/strax/pull/777</li> <li>Add hot fix for copy_to_buffer by @WenzDaniel in https://github.com/AxFoundation/strax/pull/785</li> <li>Upgrade compare-metadata function by @KaraMelih in https://github.com/AxFoundation/strax/pull/778</li> <li>Add warning by @WenzDaniel in https://github.com/AxFoundation/strax/pull/776</li> </ul> <p><strong>Full Changelog</strong>: https://github.com/AxFoundation/strax/compare/v1.5.4...v1.5.5</p&gt
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