Recurrence of Solitary Fibrous Tumor/Hemangiopericytoma Could Be Predicted by Ki-67 Regardless of Its Origin

Since the discovery of the NAB2-STAT6 gene fusion in 2013, solitary fibrous tumor (SFT) and hemangiopericytoma (HPC) have been considered the same disease. STAT6 nuclear stain is approved as a highly sensitive and specific marker to diagnose SFT/HPC from other tumors with similar histology. As the next step, detection of fusion variants that may predict clinical malignancy of SFT/HPC has been attempted. However, no fusion variants with a clear relation to malignancy have been identified. In this study, the clinical and histological backgrounds of 23 Japanese patients diagnosed with SFT/HPC from 2000 to 2019 at Kochi University Hospital were examined to identify factors potentially related to recurrence. A significant relationship to recurrence was detected for mitosis ≥ 1/10 HPF (400×), necrosis, and Ki-67>5%. These findings indicate that a deliberate investigation of histological features such as mitosis and necrosis is crucial for the clinical observation of SFT/ HPC patients. In addition, Ki-67 was revealed to be a useful parameter to predict recurrence in SFT/HPC patients

Surface-Active and Photochemical Properties of Sodium p-Dodecylbenzylsulfate in Aqueous Solution

An ultraviolet (UV)-degradative anionic surfactant, sodium p-dodecylbenzylsulfate, was prepared and its surface-active and photochemical properties in water were examined. The surface activities such as solubilizing, foaming, and dispersing powers were as good as those of synthetic detergents, linear alkylbenzenesulfonate and sodium dodecylsulfate. Upon UV irradiation, the surfactant was degraded to give p-dodecylbenzyl alcohol, a nonsurfactant.ArticleJOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY. 33(6):812-815 (2012)journal articl