80 research outputs found
Microbial interaction of periodontopathic bacteria and Epstein-Barr virus and their implication of periodontal diseases
AbstractEpstein-Barr virus (EBV) is a ubiquitous human gamma herpesvirus that infects more than 90% of the world's population. EBV infection causes several human diseases, including infectious mononucleosis, autoimmune disorders, and a number of malignancies. Interestingly, evidence accumulated over the past 10 years supports the role for EBV as a pathogenic agent of periodontal disease because bacterial activities alone do not explain several of its clinical characteristics. Despite this, it remains unclear how EBV is reactivated in the oral cavity and how activated EBV leads to the progression of periodontal diseases. We focused on the microbial interaction between bacteria and viruses in the etiology of infectious disease and found that the periodontal pathogen Porphyromonas gingivalis could induce EBV reactivation via chromatin modification. Our observations provide evidence for a possible microbial interaction between bacteria and EBV that may contribute to the pathogenesis of EBV-related diseases. This review describes the molecular mechanisms involved in the maintenance of EBV latency and its reactivation by periodontopathic bacteria. In addition, we discuss possible mechanisms by which EBV reactivation may facilitate progression of periodontal disease in infected individuals
Porcine Enamel Protein Fractions Contain Transforming Growth Factor‐β1
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141064/1/jper1688.pd
Intrinsic pinning property of FeSe0.5Te0.5
The intrinsic pinning properties of FeSe0.5Te0.5, which is the superconductor
with Tc of about 14 K, were studied by the analysis of magnetization curves by
the extended critical state model. In the magnetization measurements by SQUID
magnetometer, the external magnetic fields were applied parallel and
perpendicular to c-axis of the sample. The critical current density Jc's under
the perpendicular field of 1 T were estimated by using the Kimishima model as
about 1.6 x 10^4, 8.8 x 10^3, 4.1 x 10^3, and 1.5 x 10^3 A/cm2 at 5, 7, 9, and
11 K, respectively, and the temperature dependence of Jc could be fitted with
the exponential law of Jc(0)xexp(-{\alpha}T /Tc) up to 9 K and power law of
Jc(0)x(1-T / Tc)n near Tc.Comment: 19 pages, 7 figure
Green functions and heat kernels of second order ordinary differential operators with discontinuous complex coefficients(Spectral and Scattering Theory and Related Topics)
Essential m-sectoriality and essential spectrum of the Schrödinger operators with rapidly oscillating complex-valued potentials
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