Evaluation formulas for a conditional Feynman integral over Wiener paths in abstract Wiener space

summary:In this paper, we introduce a simple formula for conditional Wiener integrals over $C_0(\mathbb{B})$, the space of abstract Wiener space valued continuous functions. Using this formula, we establish various formulas for a conditional Wiener integral and a conditional Feynman integral of functionals on $C_0(\mathbb{B})$ in certain classes which correspond to the classes of functionals on the classical Wiener space introduced by Cameron and Storvick. We also evaluate the conditional Wiener integral and conditional Feynman integral for functionals of the form $$\exp \biggl \lbrace \int _0^T \theta (s, x(s))\mathrm{d}\eta (s) \biggr \rbrace$$ which are of interest in Feynman integration theories and quantum mechanics

Novel a‐Si:H TFT pixel circuit for electrically stable top‐anode light‐emitting AMOLEDs

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/92120/1/1.2770853.pd

Short-Term Effects of Combined Serial Casting and Botulinum Toxin Injection for Spastic Equinus in Ambulatory Children with Cerebral Palsy

PURPOSE: The purpose of this paper is to test the hypothesis that combination therapy of serial cast and botulinum toxin type A (BTX-A) injection can further enhance the effects of a BTX-A injection in ambulant children with cerebral palsy (CP) who have an equinus foot. MATERIALS AND METHODS: Children in group A (30 legs of 21 children) received a serial casting application after an injection of BTX-A, and children in group B (25 legs of 17 children) received only a BTX-A injection. Assessments were performed before the intervention and 1 month after the intervention. RESULTS: After the intervention, there were significant improvements in tone, dynamic spasticity, and passive range of motion (ROM) in both groups. However, the changes were greater in group A than in group B. Dimension D (standing) in Gross Motor Function Measure (GMFM)-66 was significantly improved in group A but not in group B. On the other hand, there were no significant changes in dimension E (walking, running, jumping) in GMFM-66 in either group. CONCLUSION: The results of our study suggest that a serial casting application after BTX-A injection can enhance the benefits of BTX-A injection in children with cerebral palsy.ope

Speech Processing Research Program

Contains an introduction and reports on five research projects.National Science Foundation FellowshipNational Science Foundation Grant MIP 87-14969U.S. Navy - Office of Naval Research Contract N00014-89-J-1489U.S. Air Force - Electronic Systems Division Contract F19628-89-K-0041National Science Foundation Fellowshi

Toxicological Study on MUNOPHIL, Water Extract of Panax ginseng and Hericium erinaceum in Rats

AbstractObjectiveAs data on the safety profile of Panax ginseng and Hericium erinaceum is lacking, the safety of these two compounds was examined in a series of toxicological studies.Materials and MethodsMUNOPHIL, the water extract mixture of Panax ginseng and Hericium erinaceum was tested in an oral subchronic 28-day toxicity study in rats at doses of 1250, 2500 and 5000 mg/kg/day.ResultsIn repeated dose toxicity studies, no mortality was observed when varying doses of the extracts were administered once daily for a period of 28 days. There were no significant differences in body weight, absolute and relative organ weights between controls and treated rats of both sexes. Hematological analysis showed no differences in most parameters examined. In the biochemistry parameter analysis, no significant change occurred. Pathologically, neither gross abnormalities nor his-topathological changes were observed. Therefore, MUNOPHIL appears to be safe and non-toxic in these studies and a no-observed adverse effect level in rats was established at 5000 mg/kg/day.ConclusionThe data could provide satisfactory preclinical evidence of safety to launch clinical trials on standardized formulation of plant extracts

Cell type–dependent variation in paracrine potency determines therapeutic efficacy against neonatal hyperoxic lung injury

AbstractBackground aimsThe aim of this study was to determine the optimal cell type for transplantation to protect against neonatal hyperoxic lung injury. To this end, the in vitro and in vivo therapeutic efficacies and paracrine potencies of human umbilical cord blood–derived mesenchymal stromal cells (HUMs), human adipose tissue–derived mesenchymal stromal cells (HAMs) and human umbilical cord blood mononuclear cells (HMNs) were compared.MethodsHyperoxic injury was induced in vitro in A549 cells by challenge with H2O2. Alternatively, hyperoxic injury was induced in newborn Sprague-Dawley rats in vivo by exposure to hyperoxia (90% oxygen) for 14 days. HUMs, HAMs or HMNs (5 × 105 cells) were given intratracheally at postnatal day 5.ResultsHyperoxia-induced increases in in vitro cell death and in vivo impaired alveolarization were significantly attenuated in both the HUM and HAM groups but not in the HMN group. Hyperoxia impaired angiogenesis, increased the cell death and pulmonary macrophages and elevated inflammatory cytokine levels. These effects were significantly decreased in the HUM group but not in the HAM or HMN groups. The levels of human vascular endothelial growth factor and hepatocyte growth factor produced by donor cells were highest in HUM group, followed by HAM group and then HMN group.ConclusionsHUMs exhibited the best therapeutic efficacy and paracrine potency than HAMs or HMNs in protecting against neonatal hyperoxic lung injury. These cell type-dependent variations in therapeutic efficacy might be associated or mediated with the paracrine potency of the transplanted donor cells

Parenchymal Neurocutaneous Melanosis in Association with Intraventricular Dermoid and Dandy-Walker Variant: A Case Report

Neurocutaneous melanosis (NCM) is a rare congenital disease that is characterized by the presence of large or multiple congenital melanocytic nevi and melanotic lesions of the central nervous system. We report here on the CT and MR imaging findings of an unusual case of NCM that was associated with intraventricular dermoid and Dandy-Walker malformation

Advanced Telecommunications and Signal Processing Program

Contains an introduction, and reports on seven research projects.Advanced Telecommunications Research ProgramAT&T FellowshipINTEL FellowshipU.S. Navy - Office of Naval Research NDSEG Graduate FellowshipMaryland Procurement Office Contract MDA904-93-C-418

The Importance of Binary Gravitational Microlensing Events Through High-Magnification Channel

We estimate the detection efficiency of binary gravitational lensing events through the channel of high-magnification events. From this estimation, we find that binaries in the separations ranges of 0.1 < s < 10, 0.2 < s < 5, and 0.3 < s < 3 can be detected with ~ 100% efficiency for events with magnifications higher than A=100, 50, and 10, respectively, where s represents the projected separation between the lens components normalized by the Einstein radius. We also find that the range of high efficiency covers nearly the whole mass-ratio range of stellar companions. Due to the high efficiency in wide ranges of parameter space, we point out that majority of binary-lens events will be detected through the high-magnification channel in lensing surveys that focus on high-magnification events for efficient detections of microlensing planets. In addition to the high efficiency, the simplicity of the efficiency estimation makes the sample of these binaries useful in the statistical studies of the distributions of binary companions as functions of mass ratio and separation. We also discuss other importance of these events.Comment: 5 pages, 1 figure, 1 tabl