An innovative artificial bee colony algorithm and its application to a practical intercell scheduling problem

<p>In this article, an innovative artificial bee colony (IABC) algorithm is proposed, which incorporates two mechanisms. On the one hand, to provide the evolutionary process with a higher starting level, genetic programming (GP) is used to generate heuristic rules by exploiting the elements that constitute the problem. On the other hand, to achieve a better balance between exploration and exploitation, a leading mechanism is proposed to attract individuals towards a promising region. To evaluate the performance of IABC in solving practical and complex problems, it is applied to the intercell scheduling problem with limited transportation capacity. It is observed that the GP-generated rules incorporate the elements of the most competing human-designed rules, and they are more effective than the human-designed ones. Regarding the leading mechanism, the strategies of the ageing leader and multiple challengers make the algorithm less likely to be trapped in local optima.</p

Additional file 1: Tables S1. of Capability of leaf interdigitation with different inverse planning strategies in Monaco: an investigation of representative tumour sites

The PTV comparative results of the leaf interdigitation plans and leaf non-interdigitation plans in NPC sites. Tables S2. The PTV comparative results of the leaf interdigitation plans and leaf non-interdigitation plans in cervical sites. Tables S3. The PTV comparative results of the leaf interdigitation plans and leaf non-interdigitation plans in prostate sites. Tables S4. The OARs parameter values of the leaf interdigitation plans and leaf non-interdigitation plans in NPC sites. Tables S5. The OARs parameter values of the leaf interdigitation plans and leaf non-interdigitation plans in cervical sites. Tables S6. The OARs parameter values of the leaf interdigitation plans and leaf non-interdigitation plans in prostate sites. Table S7. Delivery efficiency of the leaf interdigitation plans and leaf non-interdigitation plans in NPC sites. Table S8. Delivery efficiency of the leaf interdigitation plans and leaf non-interdigitation plans in cervical sites. Table S9. Delivery efficiency of the leaf interdigitation plans and leaf non-interdigitation plans in prostate sites. (DOCX 23 kb

The impact of b-values on diffusion-weighted imaging radiomic features and a retrospective study to characterize the hepatic cirrhosis

DWI RADIOMICS OF HEPATIC CIRRHOSIS-PEER

Study of dynamic CT radiomic features to assist the accurate diagnosis of HCC

<p><b>Figure 1 </b><a></a><a>Delineation of an HCC in each of the five phases on CT images<b> (</b>A: plain scan phase (PSP), B: arterial phase (AP), C: portal venous phase (PVP), D: </a><a>venous</a> <a>phase</a> (VP), E: delayed phase (DP))<b></b></p> <p><b>Figure 2</b> The variation trend of the GTV radiomic features throughout the 5 phases</p> <p><b>Figure 3</b> <a></a><a>The comparison of dynamic trends of the CT radiomic features of the GTV and normal liver tissue</a></p> <p><b>Figure 4</b> ROC curves of 4 radiomic features in the five phases <a></a><a>(A: plain scan phase, B: arterial phase, C: portal venous phase, D: </a><a>venous</a> <a>phase</a>, E: delayed phase）</p> <p><b>Table 1</b> The radiomic feature change rate differences between normal liver tissue and the GTV in the different time phases</p> <p><b>Table 2</b> The AUC values and Youden index of 4 radiomic features in the different phases</p> <p><a><b>Table S1</b></a> <a></a><a>The extracted radiomic features in this study</a></p

2D Ligand interaction diagram of compound 3k with DNA gyrase.

<p>2D Ligand interaction diagram of compound 3k with DNA gyrase.</p

Hydrogen Bond Lengths (Å) and Bond Angles (°) of compound 3n.

<p>Hydrogen Bond Lengths (Å) and Bond Angles (°) of compound 3n.</p

Crystal packing of the compound 3n.

<p>Crystal packing of the compound 3n.</p

Synthesis, Structure and Antibacterial Activity of Potent DNA Gyrase Inhibitors: N′-Benzoyl-3-(4-Bromophenyl)-1<i>H</i>-Pyrazole-5-Carbohydrazide Derivatives

<div><p>A total of 19 novel (<b>3a–3s</b>) N′-benzoyl-3-(4-bromophenyl)-1<i>H</i>-pyrazole-5-carbohydrazide analogs were designed, synthesized, and evaluated for biological activities as potential DNA gyrase inhibitors. The results showed that compound <b>3k</b> can strongly inhibit <i>Staphylococcus aureus</i> DNA gyrase and <i>Bacillus subtilis</i> DNA gyrase (with IC₅₀ of 0.15 µg/mL and 0.25 µg/mL, respectively). Structure-activity relationships were also discussed base on the biological and docking simulation results.</p></div

The receptor surface model with compound 3k.

<p>The receptor surface model with compound 3k.</p

Metal-Free Synthesis of Oxindoles via (NH₄)₂S₂O₈‑Mediated Halocarbocyclization of Alkenes in Water

A metal-free synthesis of oxindoles was achieved through the (NH₄)₂S₂O₈-mediated halocarbocyclization of alkenes. This protocol provides a practical and environmentally benign method for the construction of halo-containing oxindoles in water. The advantages of this reaction are its good functional group tolerance and mild reaction conditions. On the basis of experimental observations, a plausible reaction mechanism is proposed