3,722 research outputs found
Nonomuraea monospora sp. nov., an actinomycete isolated from cave soil in Thailand, and emended description of the genus Nonomuraea
A novel actinomycete, designated strain PT708T, was isolated from cave soil collected in Pha Tup Cave Forest Park, Nan province, Thailand. It produced compounds with antimicrobial and anticancer activities. Its chemotaxonomic properties were consistent with those of members of the genus Nonomuraea . The major menaquinone was MK-9(H4), with minor amounts of MK-9(H6), MK-9(H2), MK-10(H2) and MK-8(H4). The polar lipid profile contained phosphatidylmonomethylethanolamine, diphosphatidylglycerol, hydroxy-phosphatidylmonomethylethanolamine, hydroxy-phosphatidylethanolamine, phosphatidylethanolamine, phosphatidylglycerol, phosphatidylinositol mannoside and phosphatidylinositol. The major fatty acids were iso-C16 : 0, 10-methyl C17 : 0, C16 : 0 and C17 : 1ω6c. Phylogenetic analysis based on 16S rRNA gene sequences indicated that strain PT708T belonged to the genus Nonomuraea and was most closely related to Nonomuraea rhizophila YIM 67092T (98.50 % sequence similarity) and Nonomuraea rosea GW 12687T (98.30 %). The genomic DNA G+C content of strain PT708T was 73.3 mol%. Unlike the recognized members of the genus Nonomuraea , the novel strain formed single spores at the tips of aerial hyphae. Based on the phenotypic, phylogenetic and genotypic evidence, strain PT708T represents a novel species of the genus Nonomuraea , for which the name Nonomuraea monospora sp. nov. is proposed. The type strain is PT708T ( = TISTR 1910T = JCM 16114T)
On-orbit radiometric calibration of SWIR bands of TANSO-FTS onboard GOSAT
The Greenhouse gases Observing SATellite (GOSAT) was launched on 23 January 2009 to monitor global distributions of carbon dioxide and methane. The Thermal And Near-infrared Sensor for carbon Observation-Fourier Transform Spectrometer (TANSO-FTS) onboard GOSAT measures the short-wavelength infrared (SWIR) spectra. Radiometric accuracy directly influences the accuracy of the retrieved greenhouse gas concentrations. From a 2.5-yr retrieval analysis of GOSAT data, we found that the minimum of the mean-squared value of the residuals (the difference between observed and fitted spectra) and the radiance adjustment factor (one of the ancillary parameters to be retrieved with the gas concentrations for adjusting the radiance level between the bands) changed with time, possibly due to inaccurate degradation correction. In this study, the radiometric degradation of TANSO-FTS was evaluated from the on-orbit solar calibration data and modeled as a function of time and wavenumber for each spectral band. The radiometric degradation of TANSO-FTS Band 1 (centered at 0.76 μm) after the launch was found to be about 4 to 6%, varying with wavenumber, whereas the other two bands (Band 2: 1.6 μm and Band 3: 2.0 μm) showed about 1% degradation and small wavenumber dependency. When we applied the new degradation model in the retrieval analysis, the above-mentioned issues disappeared
Locking Local Oscillator Phase to the Atomic Phase via Weak Measurement
We propose a new method to reduce the frequency noise of a Local Oscillator
(LO) to the level of white phase noise by maintaining (not destroying by
projective measurement) the coherence of the ensemble pseudo-spin of atoms over
many measurement cycles. This scheme uses weak measurement to monitor the phase
in Ramsey method and repeat the cycle without initialization of phase and we
call, "atomic phase lock (APL)" in this paper. APL will achieve white phase
noise as long as the noise accumulated during dead time and the decoherence are
smaller than the measurement noise. A numerical simulation confirms that with
APL, Allan deviation is averaged down at a maximum rate that is proportional to
the inverse of total measurement time, tau^-1. In contrast, the current atomic
clocks that use projection measurement suppress the noise only down to the
level of white frequency, in which case Allan deviation scales as tau^-1/2.
Faraday rotation is one of the possible ways to realize weak measurement for
APL. We evaluate the strength of Faraday rotation with 171Yb+ ions trapped in a
linear rf-trap and discuss the performance of APL. The main source of the
decoherence is a spontaneous emission induced by the probe beam for Faraday
rotation measurement. One can repeat the Faraday rotation measurement until the
decoherence become comparable to the SNR of measurement. We estimate this
number of cycles to be ~100 cycles for a realistic experimental parameter.Comment: 18 pages, 7 figures, submitted to New Journal of Physic
SHG microscopic observations of polar state in Li-doped KTaO3 under electric field
Incipient ferroelectric KTaO3 with off-center Li impurity of the critical
concentration of 2.8 mol% was investigated in order to clarify the dipole glass
state under electric field. Using optical second-harmonic generation (SHG)
microscope, we observed a marked history dependence of SHG intensity through
zero-field cooling (ZFC), zero-field heating (ZFH), field heating after ZFC
(FH/ZFC) and FH after field cooling (FH/FC). These show different paths with
respect to temperature: In the ZFC/ZFH process, weak SHG was observed at low
temperature, while in the FH/ZFC process, relatively high SHG appears in a
limited temperature range below TF depending on the field strength, and in the
FC and FH/FC processes, the SHG exhibits ferroelectric-like temperature
dependence: it appears at the freezing temperature of 50K, increases with
decreasing temperature and has a tendency of saturation. These experimental
results strongly suggest that dipole glass state or polar nano-clusters which
gradually freezes with decreasing temperature is transformed into
semi-macroscopic polar state under the electric field. However at sufficiently
low temperature, the freezing is so strong that the electric field cannot
enlarge the polar clusters. These experimental results show that the polar
nano-cluster model similar to relaxors would be more relevant in KTaO3 doped
with the critical concentration of Li. Further experiments on the anisotropy of
SHG determine that the average symmetry of the field-induced polar phase is
tetragonal 4mm or 4, which is also confirmed by the X-ray diffraction
measurement.Comment: 26 pages, 8 figures, 1 tabl
Estimation of the sea surface drag coefficient based on wave data
The sea surface drag coefficient, an important parameter for the energy transfer process in wave prediction model, is generally expressed by a linear function of wind speed. However, it seems inadequate to apply these equations for strong wind conditions because these equations were deduced from the observational or the\ud
experimental data under wind speed of lower than 25m/s at fastest. To solve this problem, a wave prediction model ADWAM which includes a data assimilation method seems effective. For the purpose of clarifying the appropriate values of the sea surface drag coefficient in high wind speed, the ADWAM was modified to estimate the sea surface drag coefficients as its control variables of the model. In this study, the sea surface drag coefficient was deduced from the actual wave observation data. As a results, the sea surface drag coefficient, unknown parameter, was confirmed to\ud
be modified from arbitrary initial value to an appropriate value. Also, it was confirmed that the sea surface drag coefficient under stormy condition can be estimated based on the wave data observed outside the storm if the waves propagated from the storm were observed
At the Zebra Crossing: Modelling Complex Decision Processes with Variable-Drift Diffusion Models
CTAD as a universal anticoagulant
The feasibility of CTAD (a mixture of citrate, theophylline, adenosine and dipyridamole) as a new anticoagulant for medical laboratory use was studied prospectively. Whole blood anticoagulated with CTAD exhibited results very similar to those of blood anticoagulated with EDTA on complete blood count and automated white cell differential except for a slight decrease in platelet count and mean platelet volume. Chemistry test data for plasma obtained from CTAD whole blood were close to those obtained for matched sera. Among coagulation tests, prothrombin time, activated partial thromboplastin time and fibrinogen concentrations were close to those obtained with citrate plasma. Based on the results, CTAD was judged to be a good candidate as a new anticoagulant
Preservation of tumour oxygen after hyperbaric oxygenation monitored by magnetic resonance imaging
Hyperbaric oxygen (HBO) has been proposed to reduce tumour hypoxia by increasing the dissolved molecular oxygen in tissue. Using a non-invasive magnetic resonance imaging (MRI) technique, we monitored the changes in MRI signal intensity after HBO exposure because dissolved paramagnetic molecular oxygen itself shortens the T1 relation time. SCCVII tumour cells transplanted in mice were used. The molecular oxygen-enhanced MR images were acquired using an inversion recovery-preparation fast low angle shot (IR-FLASH) sequence sensitizing the paramagnetic effects of molecular oxygen using a 4.7 tesla MR system. MR signal of muscles decreased rapidly and returned to the control level within 40 min after decompression, whereas that of tumours decreased gradually and remained at a high level 60 min after HBO exposure. In contrast, the signal from the tumours in the normobaric oxygen group showed no significant change. Our data suggested that MR signal changes of tumours and muscles represent an alternation of extravascular oxygenation. The preserving tumour oxygen concentration after HBO exposure may be important regarding adjuvant therapy for cancer patients. © 2000 Cancer Research Campaig
2.1 Long-term safety and efficacy of tocilizumab in children with systemic juvenile idiopathic arthritis (JIA)
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