5,681 research outputs found

    Poly[(N,N-dimethyl­formamide-κO)tris­(μ-naphthalene-1-acetato)terbium(III)]

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    In title compound, [Tb(C12H9O2)3(C3H7NO)]n, the Tb atom is nine-coordinated by nine O atoms from three naphthalene-1-acetate and one N,N-dimethyl­formamide ligands. The Tb atoms are linked by three bridging naphthalene-1-acetate ligands into a chain parallel to the b axis. Further stabilization of the structure is accomplished by non-classical C—H⋯O hydrogen bonds and C—H⋯π interactions

    Bis[4-(2-hy­droxy­benzyl­idene­amino)­benzoato-κO 1]tetra­kis­(methanol-κO)cadmium

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    In the title mononuclear complex, [Cd(C14H10NO3)2(CH3OH)4], the Cd2+ cation is situated on an inversion centre. It exhibits a distorted octa­hedral coordination, defined by two carboxyl­ate O atoms from two monodentate anions and by four O atoms from four methanol mol­ecules. The crystal structure comprises intra­molecular O—H⋯O and O—H⋯N, and inter­molecular O—H⋯O hydrogen bonds. The latter help to construct a layered structure extending parallel to (100)

    TGF-β1 and IL-10 expression in epithelial ovarian cancer cell line A2780

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    Purpose: Ovarian cancer is a leading cause of death among gynaecological malignancies. Transforming growth factor-beta 1 (TGF β1) and interleukin-10 (IL-10) are cytokines in the tumour microenvironment and may play critical roles in immune suppression. This study highlights these roles and immunosuppressive functions in epithelial ovarian cancer (EOC).Methods: TGF-β1 and IL-10 expression was compared in malignant, benign, and borderline cancerous tissues and tumour-free tissue by immunohistochemistry. Relationships among the levels of these cytokines, correlation of expression level with EOC prognosis, and cytokine involvement in immunosuppression were investigated.Results: Immunohistochemical analysis of TGF-β1 and IL-10 in epithelial cells showed the presence of epithelial, borderline, and benign ovarian tumour growth, and normal ovarian growth. TGF-β1 (P = 0.121), residual tumour after surgery (P = 0.231) and standard chemotherapy (P = 0.121) were prognostic factors for EOC. There were no significant differences in clinicopathologic factors between specimens expressing TGF-β1 at low and high levels, indicating that TGF-β1 is an independent factor in EOC diagnosis. Higher concentrations of TGF-β1 (1754.690 ± 3416.487 pg/ml) and IL 10 (2731.7101 ± 6.1613 pg/ml) were observed in A2780-conditioned than in control medium.Conclusion: TGF-β1 and IL-10 play pivotal roles in EOC and can lead to immune evasion. Targeting these cytokines for tumour treatment, specifically at early stages, may prevent tumour progression.Keywords: Epithelial ovarian cancer, TGF-β1, IL-10, histopatholog

    Design of Virtual Objects Using Transformation Optics

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    Two structures of virtual targets filled with metamaterials are investigated through transformation optics to tailor the specific electromagnetic fields into desired spatial patterns. One virtual structure is a square column object transformed from a dielectric cylinder and the other virtual structure is a cylinder object transformed from a dielectric square column. Because the electromagnetic parameters in the virtual objects are obtained from real objects by the method of transformation optics, the scattering fields of virtual structures are the same as those of the real objects. The numerical simulations further prove the correction of theoretical results

    Theoretical study of small signal modulation behavior of Fabry-Perot Germanium-on-Silicon lasers

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    This work investigated the small signal performance of Fabry-Perot Ge-on-Si lasers by modeling and simulations. The 3dB bandwidth dependence on the structure parameters such as poly-Si cladding thickness, Ge cavity width and thickness, and minority carrier lifetime were studied. A 3dB bandwidth of 33.94 GHz at a biasing current of 270.5 mA is predicted after Ge laser structure optimization with a defect limited carrier lifetime of 1 ns

    Quasi-periodic Variations of Coronal Mass Ejections with Different Angular Widths

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    Coronal mass ejections (CMEs) are energetic expulsions of organized magnetic features from the Sun. The study of CME quasi-periodicity helps establish a possible relationship between CMEs, solar flares, and geomagnetic disturbances. We used the angular width of CMEs as a criterion for classifying the CMEs in the study. Based on 25 years of observational data, we systematically analyzed the quasi-periodic variations corresponding to the CME occurrence rate of different angular widths in the northern and southern hemispheres, using frequency and time-frequency analysis methods. There are various periods for CMEs of different angular widths: 9 months, 1.7 years, and 3.3-4.3 years. Compared with previous studies based on the occurrence rate of CMEs, we obtained the same periods of 1.2(+-0.01) months, 3.1(+-0.04) months, ~6.1(+-0.4) months, 1.2(+-0.1) years, and 2.4(+-0.4) years. We also found additional periods of all CMEs that appear only in one hemisphere or during a specific solar cycle. For example, 7.1(+-0.2) months and 4.1(+-0.2) years in the northern hemisphere, 1(+-0.004) months, 5.9(+-0.2) months, 1(+-0.1) years, 1.4(+-0.1) years, and 2.4(+-0.4) years in the southern hemisphere, 6.1(+-0.4) months in solar cycle 23 (SC23) and 6.1(+-0.4) months, 1.2(+-0.1) years, and 3.7(+-0.2) years in solar cycle 24 (SC24). The analysis shows that quasi-periodic variations of the CMEs are a link among oscillations in coronal magnetic activity, solar flare eruptions, and interplanetary space.Comment: 18 pages, 8 figures, 4 tables, Accepted by AP

    Did the nHZ Gravitational Waves Signatures Observed By NANOGrav Indicate Multiple Sector SUSY Breaking?

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    Discrete R symmetries always play an important role in low energy SUSY. The spontaneously broken of such discrete R symmetries, for example, by gaugino condensation, can lead to domain walls, which need to be either inflated away or collapse to avoid cosmic difficulties. We propose that explicitly R symmetry violation needed for collapse of domain walls can be the consequence of multiple sector SUSY breaking. The consistency constraints for the generation of non-problematic domain walls from gaugino condensation are discussed. We also study the emitted gravitational waves related to the collapse of domain walls. We find that, for SUSY breaking scale of order O(1){\cal O}(1) GeV{\rm GeV} in one of the sequestered sector (and also a low reheating temperature of order MeV{\rm MeV} if the reheating is not completed when the domain walls collapse), the peak frequency of gravitational waves emitted can lie at nHz. Such a low SUSY breaking scale can be consistency and natural in multiple sector SUSY breaking scenario. The GWs signal by NANOGrav could be a signal of such multiple sector SUSY breaking scenario and it may also indicate the existences of light goldstini at eV{\rm eV} mass scale.Comment: 13 page

    Quantum super-resolution for imaging two pointlike entangled photon sources

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    We investigate the resolution for imaging two pointlike entangled sources by using the method of the moments and the spatial-mode demultiplexing (SPADE), where the pointlike entangled sources can be generated by injecting single-mode sources with arbitrary quantum statistics distribution into an optical parametric amplifier (OPA). We demonstrate that the separation estimation sensitivity is mainly determined by the photon distribution in each detected modes and it can be enhanced by either increasing the squeezed parameter of the OPA or eliminating the relative phase difference of the entangle sources. Furthermore, in the limiting case of infinitely small source separation, the usage of entangled sources can have better resolution than those using incoherent and coherent sources. The results here can find important applications for the quantum super-resolution imaging and quantum metrology
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