1,331 research outputs found

    A New Solution of the Yang-Baxter Equation Related to the Adjoint Representation of UqB2U_{q}B_{2}

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    A new solution of the Yang-Baxter equation, that is related to the adjoint representation of the quantum enveloping algebra UqB2U_{q}B_{2}, is obtained by fusion formulas from a non-standard solution.Comment: 16 pages (Latex), Preprint BIHEP-TH-93-3

    Radiative transitions in charmonium from Nf=2N_f=2 twisted mass lattice QCD

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    We present a study for charmonium radiative transitions: J/ψηcγJ/\psi\rightarrow\eta_c\gamma, χc0J/Ψγ\chi_{c0}\rightarrow J/\Psi\gamma and hcηcγh_c\rightarrow\eta_c\gamma using Nf=2N_f=2 twisted mass lattice QCD gauge configurations. The single-quark vector form factors for ηc\eta_c and χc0\chi_{c0} are also determined. The simulation is performed at a lattice spacing of a=0.06666a= 0.06666 fm and the lattice size is 323×6432^3\times 64. After extrapolation of lattice data at nonzero Q2Q^2 to 0, we compare our results with previous quenched lattice results and the available experimental values.Comment: typeset with revtex, 15 pages, 11 figures, 4 table

    Assessment of mitochondrial dysfunction and implications in cardiovascular disorders

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    Mitochondria play a pivotal role in cellular function, not only acting as the powerhouse of the cell, but also regulating ATP synthesis, reactive oxygen species (ROS) production, intracellular Ca2+ cycling, and apoptosis. During the past decade, extensive progress has been made in the technology to assess mitochondrial functions and accumulating evidences have shown that mitochondrial dysfunction is a key pathophysiological mechanism for many diseases including cardiovascular disorders, such as ischemic heart disease, cardiomyopathy, hypertension, atherosclerosis, and hemorrhagic shock. The advances in methodology have been accelerating our understanding of mitochondrial molecular structure and function, biogenesis and ROS and energy production, which facilitates new drug target identification and therapeutic strategy development for mitochondrial dysfunction-related disorders. This review will focus on the assessment of methodologies currently used for mitochondrial research and discuss their advantages, limitations and the implications of mitochondrial dysfunction in cardiovascular disorders

    Spontaneous weaving: 3D porous PtCu networks with ultrathin jagged nanowires for highly efficient oxygen reduction reaction

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    The final publication is available at Elsevier via http://dx.doi.org/10.1016/j.apcatb.2018.04.035 © 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/We report a simple and efficient surfactant-free method to prepare 3D porous PtCu networks with ultrathin jagged nanowires and controllable composition. The morphological evolution and the influential effects of the important experimental parameters on the PtCu networks have been systematically studied. Relative to commercial Pt/C and Pt black catalysts, these porous PtCu networks exhibit much better activity and remarkably improved durability towards the oxygen reduction reaction (ORR). The excellent ORR performance could be attributed to their structural features, including the core-shell nanostructures with a Pt-skin, the 3D porous networks with high surface area, and the ultrathin (3.6 nm) jagged nanowires with plentiful edge/corner atoms. Notably, this method can be facilely extended to obtain PtCuAu trimetallic nanowire networks with high porosity, which exhibits its robustness for preparing novel 3D porous nanostructures with great potential in various catalytic applications.Natural Sciences and Engineering Research Council of Canada (NSERC) University of Waterloo, and the Waterloo Institute for Nanotechnology. NSERC, Catalysis Research for Polymer Electrolyte Fuel Cells (CaRPE FC) Network administered from Simon Fraser || Grant No. APCPJ 417858-1

    Spectrum-effect relationships between high performance liquid chromatography fingerprint and analgesic property of Anisodus tanguticus (Maxim) Pascher (Solanaceae) roots

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    Purpose: To investigate the spectrum-effect relationships between high performance liquid chromatography with photodiode array detection (HPLC-DAD) fingerprint and analgesic activity of Anisodus tanguticus (Maxim.) Pascher (Solanaceae) (AT)  roots.Methods: Analgesic activity of AT roots was evaluated by acetic acid-induced writhing test in mice. Fingerprint of AT roots was established by HPLC-DAD. After oral administration of AT roots extract, intra-gastric contents of caffeoylputrescine, anisodine, fabiatrin, scopolin, scopolamine, anisodamine and atropine in mice were determined by HPLC-DAD. Spectrum-effect relationships between HPLCDAD fingerprint and analgesic activity were investigated using bivariate correlation analysis.Results: Following treatment with different batches of AT roots extract, acetic acid-induced writhing responses in mice were inhibited significantly (p < 0.05 or 0.01), with inhibitions of 26.62 - 55.13 %, relative to the control group. Sixteen common peaks were obtained by fingerprint analysis. Peaks 1, 2, 6, 7, 8, 9 and 12 were identified as caffeoylputrescine, anisodine, fabiatrin, scopolin, scopolamine, anisodamine and atropine, respectively. Bivariate correlation analysis between analgesic activity of AT roots and 16 common peaks areas indicated the  contributions of 16 common peaks to analgesic activity of AT roots. Surprisingly, bivariate correlation analysis between analgesic activity of AT roots and intragastric contents of above-named 7 constituents revealed that the contributions of the 7 constituents to analgesic activity of AT roots were different from those based on their peak areas.Conclusion: This study provides scientific justification for the investigation of the active constituents of AT root with a view to its standardization.Keywords: Anisodus tanguticus root, Analgesic activity, HPLC-DAD fingerprint,  Bivariate correlation analysi
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