818 research outputs found

    Vesseled Cultures; Figures of Diasporic Comforts

    Get PDF
    The Domestic sphere of the Chinese American home is a promising site where continuous identities and memories of routine name are at play. In the kitchen, engaging in rituals of food making - a natural home endeavor- fosters reconnection and reconciliation with a past identity long forgotten. Architectural extrapolation is then seen through means of practices like fermenting vegetables and observation of domestic rituals between the individuals and their surroundings - whether it be the orchestration of food (the process), the jar in which the vegetables and brine rest (the vessel), or the patterns of kitchen utilities being used (the environment). From defamiliarizing these built constructs, we aim to challenge the often independent and disconnected nature of pickling by focusing on reconstructing objects made for Chinese American diaspora. These objects will be constructed to reflect their emerging sensibilities, providing intrinsic comfort in the practices they dictate and serving as a living heirloom echoing forgotten identity

    mHealth in China and the United States: How Mobile Technology is Transforming Healthcare in the World's Two Largest Economies

    Get PDF
    In this paper, we explore ways mobile technology can help with these difficulties. Specifically, we look at avenues through which mobile devices boost productivity, aid communications, and help providers improve affordability, access, and treatment. Using data drawn from China and the United States as well as global trends, we look at recent developments andemerging opportunities in mobile health, or mHealth. We argue that mobile technology assists patients, health providers, and policymakers in several different respects. It helps patients by giving them tools to monitor their health conditions and communicate those results to physicians. It enables health providers to connect with colleagues and offers alternative sources of information for patients. It is also an important tool to inform policymakers on health delivery and medical outcomes

    Genetic Polymorphisms In Estrogen-related Genes And The Risk Of Breast Cancer Among Han Chinese Women

    Get PDF
    Exposure to high levels of estrogen is considered an important risk factor for susceptibility to breast cancer. Common polymorphisms in genes that affect estrogen levels may be associated with breast cancer risk, but no comprehensive study has been performed among Han Chinese women. In the present study, 32 single-nucleotide polymorphisms (SNPs) in estrogen-related genes were genotyped using the MassARRAY IPLEX platform in 1076 Han Chinese women. Genotypic and allelic frequencies were compared between case and control groups. Unconditional logistic regression was used to assess the effects of SNPs on breast cancer risk. Associations were also evaluated for breast cancer subtypes stratified by estrogen receptor (ER) and progesterone receptor (PR) status. Case-control analysis showed a significant relation between heterozygous genotypes of rs700519 and rs2069522 and breast cancer risk (OR = 0.723, 95% CI = 0.541-0.965, p = 0.028 and OR = 1.500, 95% CI = 1.078-2.087, p = 0.016, respectively). Subgroup comparisons revealed that rs2446405 and rs17268974 were related to ER status, and rs130021 was associated with PR status. Our findings suggest that rs700519 and rs2069522 are associated with susceptibility to breast cancer among the Han Chinese population and have a cumulative effect with three other identified SNPs. Further genetic and functional studies are needed to identify additional SNPs, and to elucidate the underlying molecular mechanisms

    The relationship between serum FSH level and ovarian response during controlled ovarian stimulation

    Get PDF
    Objectives: To evaluate whether serum follicle stimulating hormone (FSH) level during the early controlled ovarian stimulation can be used as a predictor of the ovarian response in the in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycles. Material and methods: The participants of this retrospective study were chosen from Reproductive Medicine Center, Weifang People’s Hospital between January 2015 and December 2020.The participants of this study met the age of 20~43 years old, anti-Müllerian hormone (AMH) ≥ 1.2 ng/mL, antral follicle count (AFC) ≥ 5, and the data was complete and no cancellation cycle. Each participant was given GnRH agonist protocol and given a fixed dose of recombinant FSH in the first four days during the controlled ovarian stimulation (COS). According to the number of oocytes retrieved, the participants were divided into two different ovarian response groups. Serum FSH level after the fourth recombinant follicle stimulating hormone (rFSH) injection were compared during the different ovarian responders. Results: The number of participants who met both the inclusion criteria and exclusion criteria was 235. Serum sFSH levels (mean: 11.76 ± 3.10 IU/L) in the inappropriate responders was significantly higher than serum sFSH levels (mean: 10.79 ± 2.52 IU/L) in the superior responders(p = 0.029). There was a weak correlation between serum sFSH levels and the number of oocytes retrieved (r = −0.134, p = 0.041). Serum sFSH levels had significant clinical valuable (p = 0.0346) in predicting the number of oocytes retrieved. Conclusions: Serum sFSH levels may be a potential marker to predict the ovarian response during the early COS in the IVF/ICSI cycles, which can guide the adjustment of the exogenous rFSH dose

    A new car-following model considering acceleration of lead vehicle

    Get PDF
    For decades, the general motors (gm) car following model has received a great deal of attention and provided a basic framework to describe the interactions between vehicles on the road. It is based on the stimulus-response assumption that the following vehicle responds to the relative speed between the lead vehicle and itself. However, some of the empirical findings show that the assumption of gm model is not always true and need some modification. For example, the acceleration of the following vehicle is very sensitive to the sign of the relative speed and because of no term in the model that directly represents the leader’s acceleration, the follower’s response to the leader’s acceleration can be retarded. This paper offers a new car-following model that can be considered as a variant of the gm model that can better capture car following behavior. The new model treats the follower’s acceleration as a proportion of a weighted sum of the leader’s acceleration and the relative speed between the lead and following vehicles. This paper compares the new model with the original gm model numerically and the characteristics of the new parameters in the model are investigated. It is also shown that the new model overcomes the shortcomings of the original gm model identified in this paper and gives us more instruments to capture the real-world car-following behavior. First published online: 28 May 201

    DNA Checkpoint and Repair Factors Are Nuclear Sensors for Intracellular Organelle Stresses-Inflammations and Cancers Can Have High Genomic Risks.

    Get PDF
    Under inflammatory conditions, inflammatory cells release reactive oxygen species (ROS) and reactive nitrogen species (RNS) which cause DNA damage. If not appropriately repaired, DNA damage leads to gene mutations and genomic instability. DNA damage checkpoint factors (DDCF) and DNA damage repair factors (DDRF) play a vital role in maintaining genomic integrity. However, how DDCFs and DDRFs are modulated under physiological and pathological conditions are not fully known. We took an experimental database analysis to determine the expression of 26 DNA D
    • …
    corecore