Observation of giant positive magnetoresistance in a Cooper pair insulator.

Ultrathin amorphous Bi films, patterned with a nanohoneycomb array of holes, can exhibit an insulating phase with transport dominated by the incoherent motion of Cooper pairs (CP) of electrons between localized states. Here, we show that the magnetoresistance (MR) of this Cooper pair insulator (CPI) phase is positive and grows exponentially with decreasing temperature T, for T well below the pair formation temperature. It peaks at a field estimated to be sufficient to break the pairs and then decreases monotonically into a regime in which the film resistance assumes the T dependence appropriate for weakly localized single electron transport. We discuss how these results support proposals that the large MR peaks in other unpatterned, ultrathin film systems disclose a CPI phase and provide new insight into the CP localization

State detection of bond wires in IGBT modules using eddy current pulsed thermography

Insulated gate bipolar transistor (IGBT) modules are important safety critical components in electrical power systems. Bond wire lift-off, a plastic deformation between wire bond and adjacent layers of a device caused by repeated power/thermal cycles, is the most common failure mechanism in IGBT modules. For the early detection and characterization of such failures, it is important to constantly detect or monitor the health state of IGBT modules, and the state of bond wires in particular. This paper introduces eddy current pulsed thermography (ECPT), a nondestructive evaluation technique, for the state detection and characterization of bond wire lift-off in IGBT modules. After the introduction of the experimental ECPT system, numerical simulation work is reported. The presented simulations are based on the 3-D electromagnetic-thermal coupling finite-element method and analyze transient temperature distribution within the bond wires. This paper illustrates the thermal patterns of bond wires using inductive heating with different wire statuses (lifted-off or well bonded) under two excitation conditions: nonuniform and uniform magnetic field excitations. Experimental results show that uniform excitation of healthy bonding wires, using a Helmholtz coil, provides the same eddy currents on each, while different eddy currents are seen on faulty wires. Both experimental and numerical results show that ECPT can be used for the detection and characterization of bond wires in power semiconductors through the analysis of the transient heating patterns of the wires. The main impact of this paper is that it is the first time electromagnetic induction thermography, so-called ECPT, has been employed on power/electronic devices. Because of its capability of contactless inspection of multiple wires in a single pass, and as such it opens a wide field of investigation in power/electronic devices for failure detection, performance characterization, and health monitoring

Magnetic Flux Periodic Response of Nano-perforated Ultrathin Superconducting Films

We have patterned a hexagonal array of nano-scale holes into a series of ultrathin, superconducting Bi/Sb films with transition temperatures 2.65 K $<T_{co} <$5 K. These regular perforations give the films a phase-sensitive periodic response to an applied magnetic field. By measuring this response in their resistive transitions, $R(T)$, we are able to distinguish regimes in which fluctuations of the amplitude, both the amplitude and phase, and the phase of the superconducting order parameter dominate the transport. The portion of $R(T)$ dominated by amplitude fluctuations is larger in lower $T_{co}$ films and thus, grows with proximity to the superconductor to insulator transition.Comment: Revised title, abstract, text, figure

Optical flow tracking method for vibration identification of out-of-plane vision

Vibration measurement based on computer vision has been extensively studied and considered as a wide-range, non-contact measurement method. In this paper, the principle of vibration measurement using out-of-plane vision has been investigated under conventional imaging condition. A measurement model for out-of-plane vision has also been demonstrated. Combined the out-of-plane vision measurement model with the optical flow motion estimation principle, a novel model of optical flow tracking method for vibration detection based on out-of-plane vision has been proposed. It enables the identification of vibration parameters without image feature extraction. Visual vibration detection experiment has been conducted with a cantilever beam and a motor cover. Experimental results have been rigorously compared with finite element simulation to verify the efficacy of the proposed method. It shows that this method can effectively identify vibration parameters of the structure without image feature extraction

SCN5A Variants: Association With Cardiac Disorders

The SCN5A gene encodes the alpha subunit of the main cardiac sodium channel Nav1.5. This channel predominates inward sodium current (INa) and plays a critical role in regulation of cardiac electrophysiological function. Since 1995, SCN5A variants have been found to be causatively associated with Brugada syndrome, long QT syndrome, cardiac conduction system dysfunction, dilated cardiomyopathy, etc. Previous genetic, electrophysiological, and molecular studies have identified the arrhythmic and cardiac structural characteristics induced by SCN5A variants. However, due to the variation of disease manifestations and genetic background, impact of environmental factors, as well as the presence of mixed phenotypes, the detailed and individualized physiological mechanisms in various SCN5A-related syndromes are not fully elucidated. This review summarizes the current knowledge of SCN5A genetic variations in different SCN5A-related cardiac disorders and the newly developed therapy strategies potentially useful to prevent and treat these disorders in clinical setting

Source and spatial distributions of particulate organic carbon and its isotope in surface waters of Prydz Bay, Antarctica, during summer

In this study, we investigated the distributions of sea-surface suspended particulate organic carbon (POC) and its stable isotope (δ13CPOC) in Prydz Bay, Antarctica, and examined the factors influencing their distribution, sources, and transport. We used measurements collected from 61 stations in Prydz Bay during the 29th Chinese National Antarctic Research Expedition, in combination with remote sensing data on sea surface temperature (SST), chlorophyll a concentration, and sea ice coverage. The POC concentration in the surface waters of Prydz Bay was 0.28–0.84 mg·L−1, with an average concentration of 0.48 mg·L−1. The δ13CPOC value ranged from −29.68‰ to −26.30‰, with an average of −28.01‰. The concentration of suspended POC was highest in near-shore areas and in western Prydz Bay. The POC concentration was correlated with chlorophyll a concentration and sea ice coverage, suggesting that POC was associated with phytoplankton production in local water columns, while the growth of phytoplankton was obviously affected by sea ice coverage. The δ13CPOC value in suspended particles decreased gradually towards the outer waters of Prydz Bay, while in eastern Prydz Bay the δ13CPOC value become gradually more negative from nearshore to deep-water areas, suggesting that δ13CPOC was mainly infl uenced by CO2 fi xation by phytoplankton. The δ13CPOC value in suspended particles near Zhongshan Station was signifi cantly negative, possibly as a result of the input of terrigenous organic matter and changes in the phytoplankton species composition in the nearshore area