37 research outputs found
Karitane Ebeveyn Kendine Güven Ölçeği: Türkçe geçerlik ve güvenirlik çalışması
Purpose: This study aims to perform validity and reliability study of the Turkish version of the Karitane Parental Self-Confidence Scale (KPSCS), developed to be used in parents with a 0-12 month old baby
Karitane Parenting Self Confidence Scale: Turkish validity and reliability study
Purpose: This study aims to perform validity and reliability study of the Turkish version of the Karitane Parental Self-Confidence Scale (KPSCS), developed to be used in parents with a 0-12 month old baby
Effects of oxygen supplementation during the last stage of incubation on broiler performance, ascites susceptibility and some physiological traits
The present study was conducted to determine the
possible use of supplemental oxygen treatment during the last 3 days of
incubation on broiler performance, ascites susceptibility and some
physiological traits. On the 18th day of incubation, fertile eggs were
divided into two groups. From 18 to 21 d, the eggs were placed in two
hatcher cabinets: one being a control at normal atmospheric conditions, % at mm Hg and the other supplemented with oxygen
at %. Oxygen supplementation had a significant effect on
initial chick weight. At 6 weeks of age, body weight, growth rate, and feed
consumption increased as partial pressure of O rose from 20.9 to
23.0%. Feed conversion ratio decreased with the increasing partial
pressure of oxygen. In the present study, general mortality and mortality
due to ascites did not differ between the groups. At 5 weeks of age, oxygen
supplementation did not cause significant changes in RBC (red blood cell
count), Hb (hemoglobin) and Glucose. However, PCV (hematocrit) increased
significantly as the partial pressure O rose from 20.9 to 23.0%.
There were no differences in the right ventricle, left ventricle + septum,
total ventricle and RV:TV (right ventricle:total ventricle) ratio between
the oxygen supplemented and control group.Effets d'un apport supplémentaire d'oxygène durant le dernier stade d'incubation sur les performances du poulet de chair, la
formation d'ascite et quelques caractères physiologiques.
La présente étude a été conduite
pour évaluer l'utilisation possible d'un apport supplémentaire
d'oxygène pendant les trois derniers jours d'incubation sur les
performances du poulet de chair, l'apparition d'ascite et quelques
paramètres physiologiques. Au 18 jour d'incubation,
les œufs fertiles ont été divisés en deux groupes. De 18
à 21 jours, les œufs ont été placés dans deux
éclosoirs, l'un (groupe témoin) sous conditions atmosphériques
normales ( % O à mmHg) et l'autre
(groupe expérimental) sous atmosphère enrichie en oxygène à
%. L'apport d'oxygène a eu un effet significatif sur
le poids initial des poussins. A six semaines d'âge, le poids corporel,
la vitesse de croissance et la consommation d'aliments ont été
accrus avec la pression partielle en oxygène la plus élevée,
alors que l'indice de consommation a été diminué. La
mortalité en général et la mortalité due à l'ascite en
particulier n'ont pas différé entre les groupes. A cinq semaines
d'âge, l'apport d'oxygène n'a provoqué aucun changement
significatif pour la numération des globules rouges, le taux
d'hémoglobine et de glucose. Toutefois, l'hématocrite a été
sensiblement augmenté lorsque la pression partielle d'O est
passée de 20,9 à 23,0 %. Aucune différence significative n'a
été observée entre les deux groupes pour le poids du ventricule
droit, le poids du ventricule gauche + septum interventriculaire, le poids
ventriculaire total et le rapport du poids du ventricule droit au poids
ventriculaire total (VD/VT).
Homozygous c.130-131 ins A (pW44X) mutation in the HAX1 gene as the most common cause of congenital neutropenia in Turkey: Report from the Turkish Severe Congenital Neutropenia Registry
WOS: 000478208700001PubMed ID: 31321910Background Severe congenital neutropenia is a rare disease, and autosomal dominantly inherited ELANE mutation is the most frequently observed genetic defect in the registries from North America and Western Europe. However, in eastern countries where consanguineous marriages are common, autosomal recessive forms might be more frequent. Method Two hundred and sixteen patients with severe congenital neutropenia from 28 different pediatric centers in Turkey were registered. Results The most frequently observed mutation was HAX1 mutation (n = 78, 36.1%). A heterozygous ELANE mutation was detected in 29 patients (13.4%) in our cohort. Biallelic mutations of G6PC3 (n = 9, 4.3%), CSF3R (n = 6, 2.9%), and JAGN1 (n = 2, 1%) were also observed. Granulocyte colony-stimulating factor treatment was given to 174 patients (80.6%). Two patients died with infectious complications, and five patients developed myelodysplastic syndrome/acute myeloblastic leukemia. The mean (+/- mean standard error) follow-up period was 129.7 +/- 76.3 months, and overall survival was 96.8% (CI, 94.4-99.1%) at the age of 15 years. In Turkey, severe congenital neutropenia mostly resulted from the p W44X mutation in the HAX1 gene. Conclusion In Turkey, mutation analysis should be started with HAX1, and if this is negative, ELANE and G6PC3 should be checked. Because of the very high percentage of consanguineous marriage, rare mutations should be tested in patients with a negative mutation screen.Scientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK); Turkish Pediatric Hematology AssociationThis study was supported by Scientific and Technological Research Council of Turkey (TUBITAK) and the Turkish Pediatric Hematology Association