67 research outputs found
Community Detection in Dynamic Networks via Adaptive Label Propagation
An adaptive label propagation algorithm (ALPA) is proposed to detect and
monitor communities in dynamic networks. Unlike the traditional methods by
re-computing the whole community decomposition after each modification of the
network, ALPA takes into account the information of historical communities and
updates its solution according to the network modifications via a local label
propagation process, which generally affects only a small portion of the
network. This makes it respond to network changes at low computational cost.
The effectiveness of ALPA has been tested on both synthetic and real-world
networks, which shows that it can successfully identify and track dynamic
communities. Moreover, ALPA could detect communities with high quality and
accuracy compared to other methods. Therefore, being low-complexity and
parameter-free, ALPA is a scalable and promising solution for some real-world
applications of community detection in dynamic networks.Comment: 16 pages, 11 figure
Multifractal and Network Analysis of Phase Transition
Many models and real complex systems possess critical thresholds at which the
systems shift from one sate to another. The discovery of the early warnings of
the systems in the vicinity of critical point are of great importance to
estimate how far a system is from a critical threshold. Multifractal Detrended
Fluctuation analysis (MF-DFA) and visibility graph method have been employed to
investigate the fluctuation and geometrical structures of magnetization time
series of two-dimensional Ising model around critical point. The Hurst exponent
has been confirmed to be a good indicator of phase transition. Increase of the
multifractality of the time series have been observed from generalized Hurst
exponents and singularity spectrum. Both Long-term correlation and broad
probability density function are identified to be the sources of
multifractality of time series near critical regime. Heterogeneous nature of
the networks constructed from magnetization time series have validated the
fractal properties of magnetization time series from complex network
perspective. Evolution of the topology quantities such as clustering
coefficient, average degree, average shortest path length, density,
assortativity and heterogeneity serve as early warnings of phase transition.
Those methods and results can provide new insights about analysis of phase
transition problems and can be used as early warnings for various complex
systems.Comment: 23 pages, 11 figure
Altered Brain Fraction Amplitude of Low Frequency Fluctuation at Resting State in Patients With Early Left and Right Bell’s Palsy: Do They Have Differences?
Purpose: Bell’s palsy refers to acute idiopathic unilateral facial nerve palsy. It is a common disorder of the main motor pathway to the facial muscles. This study aimed to investigate the abnormal fraction amplitude of low frequency fluctuation (fALFF) of the brain in patients with early left and right Bell’s palsy.Materials and Methods: Sixty-seven patients (left 33, right 34) and 37 age- and sex-matched healthy controls underwent resting-state functional magnetic resonance imaging (R-fMRI) examination. The fALFF values were measured from all subjects and were compared among the left palsy, right palsy, and control groups. Then, correlations between the Toronto Facial Grading System (TFGS) scores of the patients and the fALFF values of abnormal brain regions were analyzed.Results: Significant group differences in fALFF values among the three groups were observed mainly in the cerebral cortical, subcortical, and deep gray matter regions. Compared with the right Bell’s palsy group, the left Bell’s palsy group showed significantly decreased fALFF values in the left temporal pole of the superior temporal gyrus (TPOsup), right supramarginal, left and right middle cingulate cortex (MCC), left superior frontal gyrus (SFG), and left precentral gyrus (PreCG), and increased fALFF values were observed in the right SFG and PreCG. Furthermore, altered fALFF values correlated positively with the TFGS scores in the left superior TPO, bilateral MCC, and right PreCG, and correlated negatively with the TFGS scores in the right SFG of the left Bell’s palsy group. Altered fALFF values correlated positively with the TFGS scores in the bilateral MCC and right PreCG and correlated negatively with the TFGS scores in the left superior TPO and SFG of the right Bell’s palsy group.Conclusion: Regulatory mechanisms seem to differ between patients with left and right early Bell’s palsy. The severity of the disease is associated with these functional alterations
Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study
Summary
Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally.
Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies
have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of
the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income
countries globally, and identified factors associated with mortality.
Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to
hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis,
exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a
minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical
status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary
intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause,
in-hospital mortality for all conditions combined and each condition individually, stratified by country income status.
We did a complete case analysis.
Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital
diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal
malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome
countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male.
Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3).
Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income
countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups).
Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome
countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries;
p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients
combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11],
p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20
[1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention
(ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety
checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed
(ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of
parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65
[0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality.
Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome,
middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will
be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger
than 5 years by 2030
Laboratory Study on Improvement of Expansive Soil by Chemically Induced Calcium Carbonate Precipitation
This paper proposes the use of calcium carbonate (CaCO3) precipitation induced by the addition of calcium chloride (CaCl2) and sodium carbonate (Na2CO3) solutions as a procedure to stabilize and improve expansive soil. A set of laboratory tests, including the free swell test, unloaded swelling ratio test, unconfined compression test, direct shear test, scanning electron microscopy (SEM) test, cyclic wetting–drying test and laboratory-scale precipitation model test, were performed under various curing periods to evaluate the performance of the CaCO3 stabilization. It is concluded from the free swell tests and unloaded swelling ratio tests that the addition of CaCl2 and Na2CO3 can profoundly decrease soil expansion potential. The reduction in expansion parameters is primarily attributed to the strong short-term reactions between clay and stabilizers. In addition, the formed cementation precipitation can decrease the water adsorption capacity of the clay surface and then consequently reduce the expansion potential. The results of unconfined compression tests and direct shear strength tests indicated that the addition of CaCl2 and Na2CO3 has a major effect on geotechnical behavior of expansive soils. Based on the SEM analyses, new cementing crystalline phases formatted by sequentially mixing CaCl2 and Na2CO3 solutions into expansive soil were found to appear in the pore space, which results in a much denser microstructure. A laboratory-scale model test was conducted, and results demonstrate the effectiveness of the CaCO3 precipitation technique in stabilizing the expansive soil procedure. The test results indicated that the concentration of CaCl2 higher than 22.0% and Na2CO3 higher than 21.2% are needed to satisfactorily stabilize expansive soil. It is proposed to implement the precipitation technique in the field by the sequential permeation of CaCl2 and Na2CO3 solutions into soils in situ
Experimental Investigation on the Post-Peak Short-Term and Creep Behavior of Fractured Sandstone
Short-term and creep tests of fractured sandstone with different degrees of damage prepared using pre-peak and post-peak unloading tests on intact sandstone were carried out using a servo-controlled rock mechanics system. Based on our experimental results, the influence of confining pressure and damage on short-term mechanical behavior of fractured sandstone with different degrees of damage was first analyzed. The results show that the peak strength, residual strength, elastic modulus, and secant modulus of fractured sandstone increase linearly with increasing confining pressure, but decrease with increasing damage. The short-term failure modes depend on the damage and change from typical shear failure modes to multiple shear failure modes with increasing damage. Then, the influence of the differential stress, confining pressure, and the degree of damage on the creep mechanical behavior of fractured specimens was further investigated. The axial instantaneous strain and creep strain increase linearly with increasing differential stress, and the specimens exhibit significant time-dependent behavior under high stress. The steady creep rate increases with increasing stress, but it decreases with increasing confining pressure and damage. However, the long-term strength and creep failure strength of fractured specimens increase linearly with increasing confining pressure, but they decrease linearly with increasing damage. The creep failure modes of fractured specimens are also the main shear failure modes, which are similar to the short-term failure modes
Experimental Investigation of Grout Nonlinear Flow Behavior through Rough Fractures
This research experimentally analyzed the impacts of various water cement (W/C) ratios of ultrafine cement grout material and normal loads FN applied to fractures on grout nonlinear flow behavior through a rough plexiglass fractured sample. An effective self-made apparatus was designed and manufactured to conduct the stress-dependent grout flow tests on the plexiglass sample containing rough fractures. At each W/C ratio, the grout pressure P increased from 0 to 0.9 MPa, and the normal loads FN ranged from 666.3 to 1467.8 N. The results of the experiments indicate that (1) the Forchheimer’s law can be used to express the results of grout nonlinear flow through rough fractures. Moreover, both nonlinear coefficient a and linear coefficient b in Forchheimer’s law decreased with the increase of the W/C ratio, but increased with the increase of the FN value. (2) For normalized transmissivity, with the increase of Re, the decline of the T/T0–Re curves means that the grout flow behavior through the fracture mainly went through three stages: the viscosity effect, then the weak inertia effect, and finally the strong inertia effect. The three stages showed that with the increase of Re, the grout flow state changed from linear to nonlinear. Moreover, with the increase of the W/C ratio, the Forchheimer coefficient β decreased. (3) At a given FN, the critical grout hydraulic gradient Jc decreased, but the critical Reynolds number Rec increased as the W/C ratio increased; at a given W/C ratio, Jc increased, but Rec decreased as FN increased
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