Translation on-the-fly add-on based on existing translation files and machine-translation

A new method for translating webpage on-the-fly is disclosed. This method use a browser add-on to auto localize the newly developed webpage or web application using existing translation files or machine-translation, so that web UI developer can detect & fix potential layout issues (including bad layout and truncation) during development time

CSMAAFL: Client Scheduling and Model Aggregation in Asynchronous Federated Learning

Asynchronous federated learning aims to solve the straggler problem in heterogeneous environments, i.e., clients have small computational capacities that could cause aggregation delay. The principle of asynchronous federated learning is to allow the server to aggregate the model once it receives an update from any client rather than waiting for updates from multiple clients or waiting a specified amount of time in the synchronous mode. Due to the asynchronous setting, the stale model problem could occur, where the slow clients could utilize an outdated local model for their local data training. Consequently, when these locally trained models are uploaded to the server, they may impede the convergence of the global training. Therefore, effective model aggregation strategies play a significant role in updating the global model. Besides, client scheduling is also critical when heterogeneous clients with diversified computing capacities are participating in the federated learning process. This work first investigates the impact of the convergence of asynchronous federated learning mode when adopting the aggregation coefficient in synchronous mode. The effective aggregation solutions that can achieve the same convergence result as in the synchronous mode are then proposed, followed by an improved aggregation method with client scheduling. The simulation results in various scenarios demonstrate that the proposed algorithm converges with a similar level of accuracy as the classical synchronous federated learning algorithm but effectively accelerates the learning process, especially in its early stage

Guidezilla extension catheter for percutaneous interventional therapy of complex lesions via a transradial approach: Case series from a single-center experience

   Background: Guide catheter extension systems have become one of the most powerful tools for address­ing complex lesions during percutaneous coronary intervention (PCI), but data on a new-generation rapid exchange extension catheter — the Guidezilla catheter — are limited. Summarized herein reports on experience using the Guidezilla catheter for complex coronary lesions via a transradial approach at the documented institution an evaluation of its safety and efficacy. Methods: A total of 25 patients (19 males and 6 females) who underwent PCI via the radial approach with the Guidezilla catheter for adequate back-up support and to facilitate equipment delivery were enrolled. The clinical, angiographic and procedural data of all 26 procedures in 25 patients (1 patient underwent two PCI procedures on different lesions) were collected to evaluate the safety and efficacy of this novel equipment. Results: The mean age of the enrolled patients was 67.7 ± 8.41 years old. The mean depth of intuba­tion was 27.90 ± 12.23 mm. Stent implantation was successful in 23 out of 26 procedures (88.5%) and failed in 3 cases: 1 case of tortuosity and severe angulation in a chronic total occlusion lesion; 1 case of an existing type B dissection (NHLBI classification system for coronary artery dissection types); and 1 case in which a stent was stripped off its balloon. None of the patients experienced coronary dissection, perforation, air embolism, pressure dampening or other major complications during the procedure. Conclusions: The Guidezilla extension catheter is an effective and safe tool that provides improved back-up support and increases the success rate of PCI for complex coronary lesion by radial access

4,4′-Bipyridinium bis(perchlorate)–4-aminobenzoic acid–4,4′-bipyridine–water (1/4/2/2)

In the structure of the title compound, C10H10N2 2+·2ClO4 −·4C7H7NO2·2C10H8N2·2H2O, the 4,4′-bipyridinium cation has a crystallographically imposed centre of symmetry. The cation is linked by N—H⋯N hydrogen bonds to adjacent 4,4′-bipyridine mol­ecules, which in turn inter­act via O—H⋯N hydrogen bonds with 4-amino­benzoic acid mol­ecules, forming chains running parallel to [30]. The chains are further connected into a three-dimensional network by N—H⋯O and O—H⋯O hydrogen-bonding inter­actions involving the perchlorate anion, the water mol­ecules and the 4-amino­benzoic acid mol­ecules. In addition, π–π stacking inter­actions with centroid–centroid distances ranging from 3.663 (6) to 3.695 (6) Å are present. The O atoms of the perchlorate anion are disordered over two sets of positions, with refined site occupancies of 0.724 (9) and 0.276 (9)

合唱活动对中老年的健康促进

Objective: Assessment of chorus activity on elderly health promotion in the level of immunity, cardiopulmonary function and mental health. Methods: 3 groups of related data within 68 members in the chorus before training, training for 6 months and 12 months were counted and analyzed by computer analysis software. Compared with 50 cases of the same age group, that was collected at the same period, about data at 3 stages. Results: The average data of three phases of chorus is: immune level (CD4): 662.38, 761.22, 764.15, left ventricular ejection fraction (LVEF): 61.11, 61.13, 62.66, short axial shortening rate (FS): 32.61, 32.88, 33.65, lung function tidal volume (TV):1.06, 1.18, 1.16, forced vital capacity (FVC): 2.76, 2.85, 2.95, 1s forced expiratory volume (FEV1): 2.31, 2.42, 2.55, 1s rate (FEV1/FVC): 83.69, 84.91, 86.44, the chase volume (MVV is): 83.25, 81.11, 81.93, mental health score values 124.44, 125.67, 126.22, in addition to that, the TV, MVV and mental health score (SF - 36) did not change outside, other indicators, including the CD4, LVEF, FS, FVC, FEV and FEV1/FVC all have different degrees of ascension. Among them, the CD4 in training after 6 months improved obviously, little change after 12 months. Cardiac function index: EF and FS were improved after training 12 months. Lung function, FEV1, FVC, FEV1/FVC are ascending after training for 6 months and for 12 months. The average data of three phases)of the other group is: immune level (CD4) : 660.24, 661.85, 661.32, left ventricular ejection fraction (LVEF): 61.33, 61.28, 61.31, short axial shortening rate (FS): 32.55, 32.38, 32.46, lung function tidal volume (TV): 1.16, 1.17, 1.16，forced vital capacity (FVC): 2.74, 2.76, 2.76, 1s forced expiratory volume (FEV1): 2.30, 2.31, 2.30,1s rate (FEV1/FVC): 83.94, 83.69, 83.33, the chase volume (MVV is): 83.35, 82.49, 83.06, mental health score values 125.31, 124.86, 124.93. No changes were found in all measurement data of all 3 stages in the other group. Conclusions: The scientific, reasonable and continued chorus training has different degrees of help for raising the level of immune, improving cardiopulmonary function and raising the level of overall health to elderly.目的  评估合唱活动对中老年人群在机体免疫水平、心肺功能及心理健康等方面的促进作用。方法  运用计算机分析软件，对某中老年合唱团68名成员在合唱训练前（第一阶段）、训练6个月（第二阶段）、训练12个月后（第三阶段）所采集的3组数据进行回顾性同比统计分析，并与同期50例同年龄段人群采集的3阶段数据进行比对。结果  合唱团三阶段3组数据各自平均值的变化如下：机体免疫水平（CD4）：662.38、761.22、764.15；心功能左室射血分数（LVEF）值：61.11、61.13、62.66；短轴缩短率（FS）值：32.61、32.88、33.65；肺功能潮气量（TV）值：1.16、1.18、1.16；用力肺活量（FVC）值：2.76、2.85、2.95，第1秒用力呼气容量（FEV1）值：2.31、2.42、2.55，1s率（FEV1/FVC）值：83.69、84.91、86.44；最大通气量（MVV）值：83.25、81.11、81.93；心理健康评分值124.44、125.67、126.22。该组数据除了TV、MVV和健康调查简表（SF-36）没有变化外，其他指标，包括CD4、LVEF、FS、FVC、FEV1和FEV1/FVC均有不同程度的提升。其中，CD4在训练6月后提升明显，第三阶段变化不大。心功能指标：LVEF和FS则在训练12个月后才有提高。肺功能FVC、FEV1和FEV1/FVC则在训练6个月、12个月两个阶段均有提升。非合唱组3阶段3组数据各自平均值的变化如下：CD4：660.24、661.85、661.32；LVEF：61.33、61.28、61.31；FS：32.55、32.38、32.46；TV：1.16、1.17、1.16；FVC：2.74、2.76、2.76；FEV1：2.30、2.31、2.30；FEV1/FVC：83.94、83.69、83.33；MVV：83.35、82.49、83.06；心理健康评分值125.31、124.86、124.93。该组所有测数据3阶段比对均无明显变化。结论  科学、合理、持续的合唱训练，对中老年免疫水平的提高、心肺功能的改善和整体健康水平的提高有着不同程度的帮助

Trans-Anastomotic Drainage Tube Placement After Hand-Sewn Anastomosis in Patients Undergoing Intersphincteric Resection for Low Rectal Cancer: An Alternative Drainage Method

Anastomotic leakage (AL) is a common complication after intersphincteric resection (ISR). It significantly reduces quality of life and causes great distress to patients. Although traditional drainage (e.g., anal and pelvic catheters) may reduce the impact of AL to some extent, their role in reducing the incidence of AL remains controversial. In this study, we developed a novel drainage technique involving the placement of drainage tubes through the gap between sutures during handsewn anastomosis, to reduce the occurrence of anastomotic leakage. We retrospectively analyzed 34 consecutive patients who underwent intersphincteric resection requiring handsewn anastomosis between February 1, 2017, and January 1, 2021. Patients were classified into the trans-anastomotic drainage tube group (TADT, n = 14) and the non-TADT group (n = 20) based on whether trans-anastomotic tube placement was performed. The incidence of postoperative complications, such as AL, was compared between the two groups, and anal function of patients at 1-year post-ISR was evaluated. Six cases of AL occurred in the non-TADT group, while none occurred in the TADT group; this difference was statistically significant (p=0.031). The TADT group also had a shorter hospital stay (p=0.007). There were no other significant intergroup differences in operation time, blood loss, pain score, anastomotic stenosis, intestinal obstruction, or incidence of wound infection. In the 30 patients (88.2%) evaluated for anal function, there were no significant intergroup differences in stool frequency, urgency, daytime/nocturnal soiling, Wexner incontinence score, or Kirwan grading. Taken together, trans-anastomotic tube placement is a novel drainage method that may reduce AL after ISR requiring handsewn anastomosis and without adversely affecting anal function