International comparison of land development rights' transfer

2008-2009 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

Stability analysis and performance design for fuzzy-model-based control system under imperfect premise matching

Author name used in this publication: F. H. F. LeungCentre for Signal Processing, Department of Electronic and Information EngineeringRefereed conference paper2007-2008 > Academic research: refereed > Refereed conference paperVersion of RecordPublishe

Stability conditions for fuzzy control systems with fuzzy feedback gains

Author name used in this publication: F. H. F. LeungCentre for Signal Processing, Department of Electronic and Information EngineeringRefereed conference paper2007-2008 > Academic research: refereed > Refereed conference paperVersion of RecordPublishe

Diagnosis of dihydropyrimidinase deficiency in a Chinese boy with dihydropyrimidinuria

published_or_final_versio

Effects of reconstituted collagen matrix on fates of mouse embryonic stem cells before and after induction for chondrogenic differentiation

Embryonic stem (ES) cells are pluripotent cells with great potential in regenerative medicine. However, controlling their differentiation toward homogeneous lineages is challenging. In this study, we aim to investigate the effects of reconstituted 3D collagen matrix on the fates of mouse ES (mES) cells before and after induction for chondrogenic differentiation. Specifically, mES cells were encapsulated and cultured in 3D collagen microspheres and exposed to induction signals at different time points. Growth characteristics and differentiation status of mES cells were then evaluated. Collagen microspheres provided a suitable microenvironment supporting mES cell growth and maintaining their undifferentiated status for certain period of time. At later time points, the proportion of undifferentiated mES cells gradually decreased, accompanied by increasing proportions of mesenchymal progenitor cells. This suggests the inductive role of collagen matrix in differentiating mES cells toward mesenchymal lineages. Moreover, a lower initial collagen monomer concentration facilitated the differentiation of mES cells into chondrogenic lineages, while induction at a later time point associated with a more advanced stage of chondrogenic differentiation. This indicates that both the initial collagen concentration and the time to induce differentiation significantly affected the fates of mES cells. This study contributes to future development of ES cell-based therapies. © Copyright 2009, Mary Ann Liebert, Inc.published_or_final_versionThe 7th Annual Meeting of the International Society for Stem Cell Research (ISSCR), Barcelona, Spain, 8-11 July 2009. In Tissue Engineering. Part A, 2009, v. 15 n. 10, p. 3071-308

Enhanced cell adhesion and proliferation on dual plasma modified titanium surfaces

Session: Biomaterials Fabrication and Synthesis: abstract no. 47INTRODUCTION: Ti-6Al-4V is widely used in present orthopedic applications, owing to a combination of good mechanical properties and excellent corrosion resistance. However, long-term success of Ti-6Al-4V implants and the completeness of their osteointegration still need to be addressed [1]. Since the biofunctionality of the implant is strongly affected by its surface characteristics, to promote osteointegration, considerable efforts have focused on modifying the surface of the implants. Alternatively, surface modification using plasma immersion ion implantation (PIII) has been developed in order to incorporate new biofunctional groups onto titanium alloy surfaces [2]. The present study aims at investigating the impact of carbon-nitrogen (Car-Nit) dual plasma surface treatment on …postprintThe 2010 North America Conference of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-NA 2010), Orlando, FL., 5-8 December 2010

MicroRNA-21 promotes survival but not functional maturation of human embryonic stem cell-derived cardiomyocytes (hESC-CMs)

published_or_final_versionThe 16th Medical Resarch Conference (MRC), The University of Hong Kong, Hong Kong, China, 22 January 2011. In Hong Kong Medical Journal, 2011, v. 17, suppl. 1, p. 35, abstract no. 5

Roles of the CHADS2 and CHA2DS2-VASc scores in post-myocardial infarction patients: risk of new occurrence of atrial fibrillation and ischaemic stroke

Poster PresentationINTRODUCTION: Patients with myocardial infarction are at risk of development of atrial fibrillation (AF) and ischaemic stroke. We sought to evaluate the prognostic performance of the CHADS2 and CHA2DS2-VASc scores in predicting new AF and/or ischaemic stroke in post-ST segment elevation myocardial infarction (STEMI) patients. METHODS: A total of 607 consecutive post-STEMI patients without previously documented AF were stud…published_or_final_versio