Practical fair anonymous undeniable signatures

We present a new model for undeniable signatures: fair-anonymous undeniable signatures. This protocol can not only preserve the privacy of the signer (i.e. anonymity) but also track the illegal utilization of the valid signatures. In addition, our model prevents the trusted centre from forging a valid signature for any signer

COLLECTING EVIDENCE OF GOOD PRACTICE AND LEADERSHIP IN A TUMULTUOUS TIME

GOAL To deliver an outcomes-focused workshop that guides participants in recognising and communicating potential sources of evidence as part of their teaching practice and leadership. BACKGROUND With the increase in education-focused roles around Australia, many tertiary institutions have established new pathways for recognition, reward and progression. However, the wave of new and transitioning tertiary educators in recent times may be unfamiliar with navigating through these new expectations and pathways. Fortunately, there are many commonalities in the reward and recognition processes for tenure, promotion and awards across institutions and a strong, supportive science education community to share experiences and advice! AIMS In this session, we will share our collective experiences and expectations across a range of Australian institutions. We will highlight proactive approaches to the collection and organisation of teaching and leadership evidence in different teaching and service contexts, paying close attention to the challenges posed by the transition to online teaching during the COVID-19 pandemic. Through this workshop, we intend to develop strategies that individual participants may employ to build their teaching and leadership portfolios. Participants from all science disciplines and academic levels are invited. DELIVERABLES Through this workshop we aim to facilitate the following: • A landscape view of commonalities in the awards and academic progression requirements across tertiary institutions; • Tips, tricks and strategies for the collection and organisation of teaching and leadership evidence; • Reflection on your own academic portfolio and plans for future evidence collection. WORKSHOP Introduction (15 minutes) We will begin this workshop by breaking down a few of the key expectations of institutions, including important similarities and differences. The promotion and award experiences of some of our most respected members within the science education community will be shared. Workshop task 1 (30 minutes) Participants will be split into small groups (2-3) to spend a short period of time evaluating the impact of different types of evidence. Coming back together, each group will summarise key points from their discussion.   Communicating your evidence (30 minutes) An important step in communicating your evidence is the consider your own, personal teaching philosophy. Through a short activity, this will be explored before splitting into small groups once more to spend time focused, through key prompts, on dot pointing some evidence of impact of their recent activities. Each member of the group will discuss their own experiences and provide each other with feedback regarding additional evidence they might seek and include. Wrap-up (15 minutes) To conclude, we will come together to once more share this experience with the wider group and discuss where-to from here. A set of tips and tricks for collecting and organising evidence will be provided and discussed

Assessment of nutritional status and nutrition impact symptoms in patients undergoing resection for upper gastrointestinal cancer: Results from the multi-centre nourish point prevalence study

Background: Identification and treatment of malnutrition are essential in upper gastrointestinal (UGI) cancer. However, there is limited understanding of the nutritional status of UGI cancer patients at the time of curative surgery. This prospective point prevalence study involving 27 Australian tertiary hospitals investigated nutritional status at the time of curative UGI cancer resection, as well as presence of preoperative nutrition impact symptoms, and associations with length of stay (LOS) and surgical complications. Methods: Subjective global assessment, hand grip strength (HGS) and weight were performed within 7 days of admission. Data on preoperative weight changes, nutrition impact symptoms, and dietary intake were collected using a purpose-built data collection tool. Surgical LOS and complications were also recorded. Multivariate regression models were developed for nutritional status, unintentional weight loss, LOS and complications. Results: This study included 200 patients undergoing oesophageal, gastric and pancreatic surgery. Malnutrition prevalence was 42% (95% confidence interval (CI) 35%, 49%), 49% lost ≥5% weight in 6 months, and 47% of those who completed HGS assessment had low muscle strength with no differences between surgical procedures (p = 0.864, p = 0.943, p = 0.075, respectively). The overall prevalence of reporting at least one preoperative nutrition impact symptom was 55%, with poor appetite (37%) and early satiety (23%) the most frequently reported. Age (odds ratio (OR) 4.1, 95% CI 1.5, 11.5, p = 0.008), unintentional weight loss of ≥5% in 6 months (OR 28.7, 95% CI 10.5, 78.6, p < 0.001), vomiting (OR 17.1, 95% CI 1.4, 207.8, 0.025), reduced food intake lasting 2–4 weeks (OR 7.4, 95% CI 1.3, 43.5, p = 0.026) and ≥1 month (OR 7.7, 95% CI 2.7, 22.0, p < 0.001) were independently associated with preoperative malnutrition. Factors independently associated with unintentional weight loss were poor appetite (OR 3.7, 95% CI 1.6, 8.4, p = 0.002) and degree of solid food reduction of <75% (OR 3.3, 95% CI 1.2, 9.2, p = 0.02) and <50% (OR 4.9, 95% CI 1.5, 15.6, p = 0.008) of usual intake. Malnutrition (regression coefficient 3.6, 95% CI 0.1, 7.2, p = 0.048) and unintentional weight loss (regression coefficient 4.1, 95% CI 0.5, 7.6, p = 0.026) were independently associated with LOS, but no associations were found for complications. Conclusions: Despite increasing recognition of the importance of preoperative nutritional intervention, a high proportion of patients present with malnutrition or clinically significant weight loss, which are associated with increased LOS. Factors associated with malnutrition and weight loss should be incorporated into routine preoperative screening. Further investigation is required of current practice for dietetics interventions received prior to UGI surgery and if this mitigates the impact on clinical outcomes

Optimal load shedding in electricity grids with renewable sources via message passing

The increased penetration of volatile and intermittent renewable energy sources challenges existing power-distribution methods as current dispatch methods were not designed to consider high levels of volatility. We suggest a principled algorithm called message passing, which complements existing techniques. It is based on statistical physics methodology and passes probabilistic messages locally to find the approximate global optimal solution for a given objective function. The computational complexity of the algorithm increases linearly with the system size, allowing one to solve large-scale problems. We show how message passing considers fluctuations effectively and prioritise consumers in the event of insufficient resource. We demonstrate the efficacy of the algorithm in managing load-shedding and power-distribution on synthetic benchmark IEEE data and discuss the role of weights in the trade-off between minimising load-shedding and transmission costs

Characterisation of adipocyte-derived extracellular vesicles released pre- and post-adipogenesis

Extracellular vesicles (EVs) are submicron vesicles released from many cell types, including adipocytes. EVs are implicated in the pathogenesis of obesity-driven cardiovascular disease, although the characteristics of adipocyte-derived EVs are not well described. We sought to define the characteristics of adipocyte-derived EVs before and after adipogenesis, hypothesising that adipogenesis would affect EV structure, molecular composition and function. Using 3T3-L1 cells, EVs were harvested at day 0 and day 15 of differentiation. EV and cell preparations were visualised by electron microscopy and EVs quantified by nanoparticle tracking analysis (NTA). EVs were then assessed for annexin V positivity using flow cytometry; lipid and phospholipid composition using 2D thin layer chromatography and gas chromatography; and vesicular protein content by an immuno-phenotyping assay. Pre-adipogenic cells are connected via a network of protrusions and EVs at both time points display classic EV morphology. EV concentration is elevated prior to adipogenesis, particularly in exosomes and small microvesicles. Parent cells contain higher proportions of phosphatidylserine (PS) and show higher annexin V binding. Both cells and EVs contain an increased proportion of arachidonic acid at day 0. PREF-1 was increased at day 0 whilst adiponectin was higher at day 15 indicating EV protein content reflects the stage of adipogenesis of the cell. Our data suggest that EV production is higher in cells before adipogenesis, particularly in vesicles <300 nm. Cells at this time point possess a greater proportion of PS (required for EV generation) whilst corresponding EVs are enriched in signalling fatty acids, such as arachidonic acid, and markers of adipogenesis, such as PREF-1 and PPARγ