'The Poets' War Revisited'

This essay seeks to explore the role played by John Marston in the so-called War of the Poets – the literary quarrel between a small group of playwrights, including Marston, Ben Jonson, Thomas Dekker, and perhaps William Shakespeare, in the late sixteenth and early seventeenth centuries. Marston's role in the War is problematic because although there are figures in his drama who might seem intended to be read as hostile portraits of Jonson, all of these figures are ambiguous, appearing to resemble Marston himself as much as they do his rival. I argue that this is because Jonson and Marston were participating in the War for very different reasons: Jonson in order to distinguish himself from his fellow satiric dramatists and Marston to emphasise the similarities between himself and his colleague. Marston may have done this in order to mock satiric dramatists as a class, but he may also have wanted to irritate Jonson by suggesting that Jonson was not as unique or individual as he liked to believe

Statistical Methods Can Confirm Industry-sponsored University Design Project Results

An industry-sponsored project was recently developed to automatically inspect soup mix packages. The industry sponsor had determined that its highest customer complaint was the absence of a flavor packet within the soup mix package. It partnered with Indiana UniversityPurdue University Indianapolis (IUPUI) to develop an automatic system to detect the missing flavor packet and remove it from the production line before the package was bulk-packed for shipment. The system was designed, built and installed by a team of Electrical Engineering Technology (EET) and Mechanical Engineering Technology (MET) students. A four-hour production test confirmed that the percentage of soup mix bags without flavor packets detected by the machine was nearly the same as the total percentage of bags without flavor packets returned by customers the previous year. But how reliable was the system over a longer period? This paper describes a semester-long IUPUI project to determine how well the inspection system performed on its production line for a ten-month period. An honors-student project was devised to use multiple statistical methods to determine whether the automatic inspection system actually improved the overall quality of the soup mix shipments; leading to reduced customer complaints. Customer complaint data for four-million units were analyzed to determine whether a significant difference of complaints existed between the production line with the inspection system and the one without. These data were analyzed using a Two Proportion Hypothesis Test to determine if there is a difference, and a Confidence Interval to estimate the size of difference. The student concluded with 95% confidence that customer complaints were significantly lower on the production line with the inspection system

IUPUI mechanical engineering technology senior assessment

This paper discusses the methods and analysis of 6-semesters of senior assessment examination data identifying the courses and subject material students found the most difficult to solve in the MET program Senior Assessment Examination. The analysis results indicate that MET 111 (Applied Statics), MET 213 (Dynamics), and MET 348 (Engineering Materials) are courses in need of potential improvement. Furthermore, subject areas such as the calculation of entropy change, the calculation of pressure drop flow through a pipe, and Hooke's Law are subject material that poses greatest problems for senior students. For the past 12 years, the Mechanical Engineering Technology (MET) Program faculty at IUPUI require all seniors to take a MET Senior Assessment Examination that is similar in content to the Fundamentals of Engineering (FE) examination. This paper discusses the methods used to provide insightful and actionable inputs for the IUPUI MET program process improvements plan. The raw data consists of test scores from 123 senior students who took the examination from 2014 through 2016. The Accreditation Board for Engineering & Technology (ABET) is an organization that ensures universities and institutions like IUPUI meet certain accreditation requirements and requires that each program develops a continuous improvement plan. The improvement plan typically consists of a compilation of student materials, employer surveys, and course evaluations used to ensure continuous improvement within a program. In 2004 IUPUI, MET program faculty decided that a standardized senior examination would be part of the program process improvement process, [1]

TATA binding protein dynamics within the cellular chromatin landscape

2013 Summer.Includes bibliographical references.RNA polymerase II (RNAPII) is a twelve subunit enzyme that catalyzes messenger (mRNA) in eukaryotic organisms. A number of essential transcription factors associate with RNAPII to form the pre-initiation complex (PIC) at gene promoter regions. TATA binding protein (TBP) is one member of the transcription machinery indispensable for transcription. At some genes, the formation of the PIC correlates strongly with the transcription output (Ptashne, 2005). These genes have a low occupancy of TBP and other PIC components prior to activation. Upon activation, these factors assemble onto the promoter and transcriptional output increases. Genes that become active upon PIC formation are termed recruitment regulated because their transcription is regulated at the level of recruitment of the PIC to the promoter. While recruitment of the PIC is required for transcription, in many cases promoter-occupancy is not correlated with transcription output. Post-recruitment gene regulation has been conserved across evolution from prokaryotes to humans (Choy et al., 1997; Guenther et al., 2007). At these genes, TBP and RNAPII and other transcription-related factors occupy the promoter region regardless of whether transcription is occurring. Upon gene activation, the occupancy increases only slightly when compared to the increase in transcript level. These genes are described as being poised. At poised genes, these transcription proteins constitutively occupy the promoter region, but it is unknown if the promoter interaction is stable or dynamic. One principal objective of my work was to investigate TBP-promoter dynamics at the poised CYC1 gene in yeast. Due to the genetic and biochemical amenability of the yeast system, studies of the transition of poised CYC1 gene to the active form have provided key insights into the sophisticated molecular requirements involved in this post-recruitment process. To describe the dynamics of the transcription complex bound at the CYC1 promoter I developed a TBP exchange assay. The results suggest that the TBP within the RNAPII transcription complex exists in a relatively stable configuration at the poised gene prior to activation. Upon induction, TBP-promoter dynamics increased at the CYC1 gene promoter. Rapid exchange during activated transcription was also observed at other genes, including at recruitment regulated gene promoters. Overall, we found rapid TBP-promoter exchange to be associated with active transcription. From my findings I propose a model where frequently clearing the promoter offers a functional advantage to support activated transcription

Multi-Disciplinary Capstone Project on Self-Replicating 3-D Printer

This paper explores the dynamics of a multi-semester multi-disciplinary team approach applied within a traditional senior capstone project that involves strong design and manufacturing components. In addition, the logistics of running a successful senior project will be discussed along with the associated problems of organization within a multi-program environment. The key drivers and motivators behind this paper are, most importantly, that multi-disciplinary teams are very common in industry and that our industrial advisory boards for Electrical Engineering Technology (EET) and Mechanical Engineering Technology (MET) suggested that we do more multi-disciplinary projects. Furthermore, this multi-disciplinary team approach will satisfy the proposed ABET/ETAC outcomes for 2016. The Proposed Revisions to the Program Criteria for Mechanical Engineering Technology and Similarly Named Programs ABET/ETAC outcomes say “The capstone experience, ideally multidisciplinary in nature, must be project based and include formal design, implementation and test processes.” (emphasis added) Faculty searched for a technology that would allow both EET and MET students to contribute equally to the success of the project, and decided upon additive manufacturing. Students have been exposed extensively through formal course material covering 3D printing technology and would be familiar with the operation of 3D printers in general. Therefore, it was reasoned a familiarity with the project goal of designing and constructing a self-replicating 3D printer would give students more confidence in tackling the difficult task of managing an extended project over both the design and manufacture phases, and mastering effective communicate across disciplines. The student team organization mirrors current industry standard operating procedures. First, the team is multidisciplinary, including EET students with programing and circuits skills and MET students with CAD, design, mechanical analysis skills. All students must demonstrate project process skills, utilizing current design for six-sigma procedures. The students learn a standard set of tools to manage the project, as well as synthesize those tools with their discipline specific knowledge. Because of the program curriculum plans, the EET students are involved in the project for two semesters. The MET students have a one semester project course; this enables one group of MET students to design the mechanical system, document their work, and pass it on to a second team for implementation. This was considered a positive based on what is typical in industry, where engineering groups are constantly interfacing. Results include observations of group member dynamics, quality of work, timeliness, budget management, and communication across disciplines. Rubrics to document student achievement of outcomes are used

Using Kolb's Learning Cycle as a Basis for Seminar-Structuring in English Literature

This paper explores how Kolb’s experiential learning cycle can be used as a way of structuring seminars in English literature in order to bring students towards a greater understanding of literary texts. Using the example of teaching Lord Byron’s poem ‘The Island’, it explains how both students’ understanding of a specific text and their core skills can be developed through a series of structured activities that relate to specific stages of the learning cycle

Monitoring 3D Printer Performance using Internet of Things (IoT) Application

Most of the current desktop 3D printers are built based on open-source designs from online communities. The largest group of open-source 3D printers is the Self-Replicating Rapid Prototype (RepRap) 3D printers. A RepRap 3D printer needs to connect to a computer or a microprocessor to feed G Code and provide interface for users to control the 3D printer. However, local computer is a relatively expensive solution comparing to the cost of a RepRap 3D printer; while the microprocessor has much less computing capability comparing to a normal computer, and cannot handle computing-intensive jobs like slicing 3D objects or generating G Code. An alternate solution is to use the internet of things (IoT) application to control and monitor 3D printers. IoT is the network of physical devices, vehicles, buildings and other items, allowing objects to be sensed and controlled remotely across existing network. IoT and 3D printing are two important new technologies, which progressively impact a lot of areas of the industries and also our everyday life. Students need to be introduced to these technologies, and get ready for future career opportunities. A multidisciplinary student project is developed to provide students access to both 3D printer and IoT platform, and also learn to collaborate with engineers from other disciplines to solve complex engineering problems. The objective of the project is to design and develop an IoT application to remote monitor the performance of a RepRap 3D printer including the printing progress and the temperatures of the heated bed and hot end. Major tasks involved in the project are: to inspect and upgrade the current 3D printer to avoid any possible compliance issues between the 3D printer and the hardware components or software tools for the IoT application; to connect the 3D printer to the Raspberry Pi microprocessor; and to design and develop the IoT application. The methods and algorithms of connecting a 3D printer to an IoT application is reported, and the IoT application interface and workflow will be presented in the results section. As a pilot study, this project provides first-hand data on the requirements of time and resources to introduce IoT to undergraduate students

Frecuencia de lesiones coronarias en pacientes sometidos a cateterismo cardiaco en Hemodinámica de Hospital Nacional Edgardo Rebagliati Martins en el año 2016

RESUMEN Objetivo: Estimar la frecuencia de lesiones coronarias en pacientes sometidos a cateterismo cardiaco en Hemodinámica del Hospital Nacional Edgardo Rebagliati Martins en el año 2016 Metodología: Estudio no experimental, descriptivo, retrospectivo de corte transversal porque se realizó utilizando los registros y base de datos del Servicio de Cardiología Intervencionista desde enero a diciembre de 2016. La población de referencia estuvo conformada por 1744 pacientes sometidos a cateterismo cardiaco según los criterios de inclusión y exclusión establecidos, los datos se ingresaron en una base de SPSS para su análisis. Resultados: Se estudiaron 300 pacientes sometidos a cateterismo cardiaco en el periodo enero-diciembre de 2016, se estima que el 70% (210 pacientes) se presentaron en el sexo masculino en comparación con el sexo femenino con 30%. La frecuencia encontrada en lo que respecta al grupo de edades, se encontró la media de edad de 69 años y las edades más frecuentes fueron de 65 a 80 años (50%) y 50 a 65 años (31 %). El 60% (180 pacientes) presentan lesión en la coronaria izquierda mientras el 40% (120 pacientes) en la coronaria derecha, respecto al número de vasos afectados se observó que el 90% de lesiones coronarias afectan a más de un vaso coronario. La vía de acceso radial se usó con mayor frecuencia con el 61% mientras que el 39% empleo la vía femoral. Conclusiones: Se presentaron más casos de lesiones coronarias en el sexo masculino, con edades que oscilan entre 65 a 80 años. Siendo la rama coronaria izquierda la más comprometida el 54% más frecuente fue la lesión en un vaso. La utilización de la vía de acceso radial con el 61% constituye una alternativa segura para el cateterismo cardiaco, que ocasiona, en un bajo porcentaje de aparición de complicaciones vasculares y relacionadas con el sitio de punción. Palabras claves: Cateterismo cardiaco, lesiones coronarias, factores de riesgo.Tesi