Thermal and Mechanical Modeling of Metal Foams for Thermal Interface Applications

We present a study on the apparent thermal resistance of metal foams as a thermal interface in electronics cooling applications. Metal foams are considered beneficial for several applications due to its significantly large surface area for a given volume. Porous heat sinks made of aluminum foam have been well studied in the past. It is not only cost effective due to the unique production process but also appealing for the theoretical modeling study to determine the performance. Instead of allowing the refrigerant flow through the open cell porous medium, we instead consider the foam as a thermal conductive network for thermal interfaces. The porous structure of metal foams is moderately compliant providing a good contact and a lower thermal resistance. We consider foam filled with stagnant air. The major heat transport is through the metal struts connecting the two interfaces with high thermally conductive paths. We study the effect of both porosity and pore density on the observed thermal resistance. Lower porosity and lower pore density yield smaller bulk thermal resistance but also make the metal foam stiffer. To understand this tradeoff and find the optimum, we developed analytic models to predict intrinsic thermal resistance as well as the contact thermal resistance based on microdeformation at the contact surfaces. The variants of these geometries are also analyzed to achieve an optimum design corresponding to maximum compliance. Experiments are carried out in accordance with ASTM D5470 standard. A thermal resistance between the range 17 and 5 K cm2/W is observed for a 0.125 in. thick foam sample tested over a pressure range of 1–3 MPa. The results verify the calculation based on the model consisting the intrinsic thermal conductivity and the correlation of constriction resistance to the actual area of contact. The area of contact is evaluated analytically as a function of pore size (5–40 PPI), porosity (0.88–0.95), orientation of struts, and the cut plane location of idealized tetrakaidecahedron (TKDH) structure. The model is developed based on assumptions of elastic deformations and TKDH structures which are applicable in the high porosity range of 0.85–0.95. An optimum value of porosity for minimizing the overall interface thermal resistance was determined with the model and experimentally validated

The Behaviour of Lead in Silica-Saturated, Copper Smelting Systems

The equilibrium distribution coefficients of lead between the matte, slag and metallic phases in the silica-saturated, copper smelting system were determined. These experiments were carried out by simultaneously equilibrating the various phases in silica crucibles at 1300℃. The conditions investigated in this study ranged from iron and copper alloy saturation at low oxygen potentials to a sulfur dioxide partial pressure of 0.1 atm and up to a matte grade of 75 wt. % Cu. The lead was found primarily in matte except in the presence of the copper alloy phase. The accumulation of lead in the copper alloy phase was pronounced, particularly at low oxygen potentials. Under conventional smelting conditions, the lead content in slag increased with increasing matte grade. The behaviour of lead was explained by proposing metallic and sulfidic species in matte and oxidic and sulfidic dissolution in slag. In this manner, the activity coefficients of the various species were calculated in their respective phases

Progress and Trends in Artificial Silk Spinning: A Systematic Review

More than 400 million years of natural selection acting throughout the arthropoda has resulted in highly specialized and energetically efficient processes to produce protein-based fibers with properties that are a source of inspiration for all. As a result, for over 80 years researchers have been inspired by natural silk production in their attempts to spin artificial silks. While significant progress has been made, with fibers now regularly outperforming silkworm silks, surpassing the properties of superior silks, such as spider dragline, is still an area of considerable effort. This review provides an overview of the different approaches for artificial silk fiber spinning and compares all published fiber properties to date which has identified future trends and challenges on the road towards replicating high performance silks

Association between longer hospitalization and development of de novo donor specific antibodies in simultaneous liver–kidney transplant recipients

© 2019, © 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. Background:De novo Donor Specific Antibodies (DSA) are considered as a risk factor for the kidney allograft outcomes in recipients after simultaneous liver–kidney transplantation (SLKT). We hypothesized that length of hospital stay (LOS) might be associated with de novo DSA development of due to the increased likelihood of receiving blood transfusions with reduced immunosuppressive regimens. Methods: This study is a single-center, retrospective cohort study consisting of 85 recipients who underwent SLKT from 2009 to 2018 in our hospital. We divided the patients into two groups according to LOS [long hospital stay (L) group (LOS \u3e14 days) and short hospital stay (S) group (LOS ≤14 days)]. Propensity score (PS) has been created using logistic regression to predict LOS greater than median of 14 days. The association between the presence of de novo DSA and LOS was assessed by logistic regression models adjusted for PS. Results: The mean age at transplantation of the entire cohort was 55.5 ± 10.1 years. Sixty percent of the recipients were male and Caucasian. Median LOS in (L) group was three-fold longer than (S) group [L: median 30 days (IQR: 21–52), S: median 8.5 days (IQR: 7–11)]. Eight patients developed de novo DSA after SLKT (9.4%), all of them were in (L) group. Longer LOS was significantly associated with higher risk of development of de novo DSA in unadjusted (OR+ each 5 days: 1.09, 95% CI:1.02–1.16) and PS adjusted (OR+ each 5 days: 1.11, 95% CI:1.02–1.21) analysis. Conclusion: Longer hospitalization is significantly associated with the development of de novo DSA in SLKT

FAS-dependent cell death in α-synuclein transgenic oligodendrocyte models of multiple system atrophy

Multiple system atrophy is a parkinsonian neurodegenerative disorder. It is cytopathologically characterized by accumulation of the protein p25α in cell bodies of oligodendrocytes followed by accumulation of aggregated α-synuclein in so-called glial cytoplasmic inclusions. p25α is a stimulator of α-synuclein aggregation, and coexpression of α-synuclein and p25α in the oligodendroglial OLN-t40-AS cell line causes α-synuclein aggregate-dependent toxicity. In this study, we investigated whether the FAS system is involved in α-synuclein aggregate dependent degeneration in oligodendrocytes and may play a role in multiple system atrophy. Using rat oligodendroglial OLN-t40-AS cells we demonstrate that the cytotoxicity caused by coexpressing α-synuclein and p25α relies on stimulation of the death domain receptor FAS and caspase-8 activation. Using primary oligodendrocytes derived from PLP-α-synuclein transgenic mice we demonstrate that they exist in a sensitized state expressing pro-apoptotic FAS receptor, which makes them sensitive to FAS ligand-mediated apoptosis. Immunoblot analysis shows an increase in FAS in brain extracts from multiple system atrophy cases. Immunohistochemical analysis demonstrated enhanced FAS expression in multiple system atrophy brains notably in oligodendrocytes harboring the earliest stages of glial cytoplasmic inclusion formation. Oligodendroglial FAS expression is an early hallmark of oligodendroglial pathology in multiple system atrophy that mechanistically may be coupled to α-synuclein dependent degeneration and thus represent a potential target for protective intervention

Fresnel lens sidewall design for imaging optics

We developed a ray tracing simulation tool for imaging systems including a Fresnel lens with a quasi-arbitrary sidewall structure. One issue with Fresnel lens is that noise in the image plane can appear from rays passing through or reflected at its sidewalls. One way to reduce it is to modify the orientation of the sidewalls so that rays will not reach the image plane. To find the best sidewall orientations, we developed a method where locally, a sidewall can freely be oriented. We could then derive the best modulation scheme for each Fresnel lens sidewall. In the case of a single imaging Fresnel lens, relative parasite noise intensity could mostly be prevented. To experimentally check our method, snapshot images were taken with single Fresnel lenses and a single spherical lens. No noticeable differences in image quality could be observed using a standard C-MOS camera. However, parasite noise could experimentally be detected with a Fresnel lens prototype when using a very high-dynamic range C-MOS camera

Blocking of lattice monopoles from the continuum in hot lattice gluodynamics

The Abelian monopoles in lattice gluodynamics are associated with continuum monopoles blocked to the lattice. This association allows to predict the lattice monopole action and density of the (squared) monopole charges from a continuum monopole model. The method is applied to the static monopoles in high temperature gluodynamics. We show that the numerical data both for the density and the action of the lattice monopoles can be described in terms of a Coulomb gas of Abelian monopoles in the continuum.Comment: 23 pages, 9 EPS figures, LaTeX2e uses JHEP3 class file; replaced to match published versio