Clinical and demographic features of pediatric burns in the eastern provinces of Turkey

Abstract Background The aim of this study is to perform a retrospective analysis of the causes of burns observed in children in the eastern provinces of Turkey. Method In this study, patients were studied retrospectively with regard to their age, sex, cause of burns, seasonal variations, social and economic factors, length of hospital stay, burned body surface area, medical history, site of injury, and mortality. Results A total of 125 patients undergoing inpatient treatment were male, (53.2%) and 110 were female (46.8%). The most common causes of burns in patients treated on an inpatient basis were scald burns (65.5%) and tandir burns (15.7%). The mean total body surface area of all the patients was 12.17+9.86%. When the patients were grouped according to tandir, cauldron, and others burn causes, a significant difference was seen between the in burn percentages caused by tandir and cauldron burns and other causes (p Pseudomonas aeruginosa (20.4%). Of the 235 patients, 61 were treated in operating rooms. During the 24-month period of the study, 2 of the 235 patients died (0.85%). Conclusion Pediatric burns in the eastern part of Turkey are different from those in other parts of Turkey, as well as in other countries. Due to the lifestyle of the region, tandir and cauldron burns, which cause extensive burn areas and high morbidity, are frequently seen in children. Therefore, precautions and educational programs related to the use of tandirs and cauldrons are needed in this region.</p

High mobility group box protein-1 (HMGB-1) as a new diagnostic marker in patients with acute appendicitis

<p/> <p>Background</p> <p>The aim of this prospective study was therefore to evaluate the diagnostic value of preoperative serum High Mobility Group Box Protein-1 (HMGB-1) levels in patients with Acute Appendicitis (AA) who show normal white blood cell count (WBC) counts.</p> <p>Method</p> <p>Our study was carried out from October 2010 through November 2010 and included 20 healthy control group participants and 60 patients who presented at the emergency department of Erzurum Training and Research Hospital in Turkey with acute abdominal pain complaints, who were pathologically diagnosed with AA after laparotomy, and who agreed to participate in the study.</p> <p>Results</p> <p>Of the 60 patients who underwent appendectomies, 36 were male and 24 were female, and of the healthy group, 12 were male and 8 female. The age averages of the patients in Groups 1, 2 and 3 were, respectively, 31.3+15.4, 34.0+16.3 and 31.0+13.1 years. The WBC averages of Groups 1, 2 and 3 were, respectively, 7.41+2.02 (x10⁹/L), 15.71+2.85 (x10⁹/L) and 8.51+1.84 (x10⁹/L). The HMGB-1 levels for Groups 1 (healthy persons), 2 (AA patients with high WBC counts ) and 3 (AA patients with normal WBC counts) were, respectively, 21.71 ± 11.36, 37.28+13.37 and 36.5 ± 17.73 ng/ml. The average HMGB-1 level of the patients with AA was 36.92 ± 15.43 ng/ml while the average HMGB-1 value of the healthy group was 21.71 ± 11.36 ng/ml.</p> <p>Conclusion</p> <p>The significantly higher levels of HMGB-1 in AA patients compared to healthy persons infer that HMGB-1 might be useful in the diagnosis of AA. Use of HMGB-1, especially in patients with normal WBC counts, will reduce the number of unnecessary explorations.</p

COVID-19 and urology: A bibliometric analysis of the literature

Aim The aims of this research were to analyse the urological literature published during the COVID-19 pandemic and to guide future research. Material and methods Between 2019 and 2021, the Web of Science (WoS) All Databases collection was searched for publications related to COVID-19 and Urology. The keywords used during this search were coronavirus-19, COVID-19, SARS-CoV-2, novel coronavirus, 2019-nCoV, pandemic and/or urology. The top 50 cited (T50) publications were also identified and summarized. Exported Microsoft Excel files, Visualization of Similarities viewer (VOSviewer) software and descriptive assessment were used for bibliometric and statistical analyses of the publications. Results In total, 582 publications related to COVID-19 and urology were identified. In these publications, the most active author, journal, country and organisation were Francesco Porpiglia, European Urology, the United States of America (USA) and La Paz University Hospital, respectively. The most commonly used keywords were telemedicine-telehealth, SARS-CoV-2, coronavirus, pandemic, residency, testicle, semen, kidney transplantation, endourology and surgery. The most worrying issues in the articles are the negative impact of COVID-19 on resident training and permanent damage to urological organs. Conclusions We analysed all the articles related to COVID-19 and urology published to date in the WoS All Databases collection. The most commonly published articles were based on clinical and outpatient practice, telemedicine, residency training, transplantation, and testicles. The long-term adverse effects of the pandemic on urology practice and especially urological organs will need to be assessed further in future research

Assessment of relationship between pain, psychological status, quality of life and body mass index

Objective: The purpose of the study is to evaluate health-related quality of life (HRQL), pain, the number of painful areas, and depression level; both to compare obesity level and these parameters, and to compare between obese and non-obese participants. Materials (Subjects) and Methods: 1875 voluntary patients were evaluated. Patients were grouped into 5 according to body mass index (BMI) values: Group 1:17-24.99kg/m2, Group 2:25-29.99kg/m2, Group 3:30-34.99kg/m2, Group 4:35-35.99kg/m2, Group 5: BMI more than 40kg/m2. Patients were asked to fulfill a questionnaire about demographic data and a number of painful areas (neck, shoulder, elbow, wrist, back, low back, knee, ankle, and temporomandibular joint). All patients were evaluated with visual analog scale (VAS), for pain, short form-36 (SF-36) for HRQL, Beck Depression Scale (BDS) for depression level. Results:We have included 1832 patients (460 male, and 1372 female) in the study: Group 1: 285(16%), Group 2: 623(34%), Group 3: 653(36%), Group 4: 190(10%), Group 5: 81(4%). When the groups was compared according to VAS scores during activity; all other groups was higher than group 1 (p<0.01). When the BDS scores were compared; depression levels were higher in group 5 than the other groups. When a number of painful areas were compared; groups 3,4,5 had higher values than groups 1,2, and group 2 had higher values than group 1 (p<0.001). Conclusion: This study evaluates pain level, the number of painful areas, physical HRQL, and depression levels of pre-obese and obese patients using VAS, BDS, and SF-36 scores and proves negative effects when compared to the healthy population. But this effect does not correlate with BMI levels.Objective: The purpose of the study is to evaluate health-related quality of life (HRQL), pain, the number of painful areas, and depression level; both to compare obesity level and these parameters, and to compare between obese and non-obese participants. Materials (Subjects) and Methods: 1875 voluntary patients were evaluated. Patients were grouped into 5 according to body mass index (BMI) values: Group 1:17-24.99kg/m2, Group 2:25-29.99kg/m2, Group 3:30-34.99kg/m2, Group 4:35-35.99kg/m2, Group 5: BMI more than 40kg/m2. Patients were asked to fulfill a questionnaire about demographic data and a number of painful areas (neck, shoulder, elbow, wrist, back, low back, knee, ankle, and temporomandibular joint). All patients were evaluated with visual analog scale (VAS), for pain, short form-36 (SF-36) for HRQL, Beck Depression Scale (BDS) for depression level. Results:We have included 1832 patients (460 male, and 1372 female) in the study: Group 1: 285(16%), Group 2: 623(34%), Group 3: 653(36%), Group 4: 190(10%), Group 5: 81(4%). When the groups was compared according to VAS scores during activity; all other groups was higher than group 1 (p<0.01). When the BDS scores were compared; depression levels were higher in group 5 than the other groups. When a number of painful areas were compared; groups 3,4,5 had higher values than groups 1,2, and group 2 had higher values than group 1 (p<0.001). Conclusion: This study evaluates pain level, the number of painful areas, physical HRQL, and depression levels of pre-obese and obese patients using VAS, BDS, and SF-36 scores and proves negative effects when compared to the healthy population. But this effect does not correlate with BMI levels

Two new locality records extend the distribution of Microtus anatolicus Kryštufek and Kefelioùlu, 2002 (Mammalia: Rodentia) into Antalya Province in Turkey

Abstract. Additional records for Microtus anatolicus Kryštufek and Kefelioùlu, 2002 which were trapped from the two localities; Bozdoùan and Kozan in Antalya Province, is reported along with their morphological measurements and karyological features and some ecological characteristics of the localities. These are the first records for M. anatolicus from these two localities, the first records from Antalya Province. Therefore the species distributional range is extended to the south of Central Mediterranean Region of Turkey into the Taurus Mountains

Combined Effects of Tauroursodeoxycholic Acid and Glutamine on Bacterial Translocation in Obstructive Jaundiced Rats:

Background: Bacterial Translocation is believed to be an important factor on mortality and morbidity in Obstructive Jaundiced. .Aims: We investigated the probable or estimated positive effects of tauroursodeoxycholic acid, which has antibacterial and regulatory effects on intestinal flora, together with glutamine on BT in an experimental obstructive jaundiced rat model. Study Design:Animal experimentation.Methods: Forty adult, male, Sprague Dawley rats were used in this study. Animals were randomised and divided into five groups of eight each: sham (Sh); control (common bile duct ligation, CBDL); and supplementation groups administered tauroursodeoxycholic acid (CBDL+T), glutamine (CBDL+G), or tauroursodeoxycholic acid plus glutamine (CBDL+TG). Blood and liver, spleen, MLN, and ileal samples were taken via laparotomy under sterile conditions for investigation of bacterial translocation and intestinal mucosal integrity and hepatic function tests on the tenth postoperative day. Results: There were statistically significant differences in BT rates in all samples except the spleen of the CBDL+TG group compared with the CBDL group (p=0.041, p=0.026, and p=0.041, respectively). Conclusion: It is essential to protect hepatic functions besides maintaining intestinal mucosal integrity in the active struggle against BT occurring in obstructive jaundice. The positive effect on intestinal mucosal integrity can be increased if glutamine is used with tauroursodeoxycholic acid, which also has hepatoprotective and immunomodulatory features

Karaciğer kist hidatik olgularımız

Amaç: Kist hidatik hastalığı halen bölgemiz ve ülkemiz için yaygın bir sağlık sorunu olarak önemini korumaktadır. Bu klinik geriye dönük çalışmada intraperitoneal rüptür nedeniyle acil cerrahi uygulanan dört olgu ile birlikte aynı dönemde tedavi edilen tüm karaciğer kist hidatik olguları incelendi. Hastalar ve Yöntemler: Ocak 2004 ve Haziran 2007 tarihleri arasında kliniğimizde karaciğer kist hidatiği nedeniyle tedavi edilen toplam 44 hastanın (24 kadın, 20 erkek; ort. yaş 47.5; dağılım 16-83) tıbbi kayıtları geriye dönük olarak incelendi. Hastalar yaş, cinsiyet, kistin yerleşim yeri, uygulanan cerrahi yöntem, hastanede kalış süresi, meydana gelen ameliyat öncesi ve sonrası komplikasyonlar ve komplikasyonlara yönelik uygulanan tedavi yöntemleri açısından irdelendi. Bulgular: İntraperitoneal rüptür nedeniyle dört hasta (%9) acil olarak ameliyat edildi. Olguların 15’inde (%34) ameliyat sonrası dönemde kist poşuna safra kaçağı oluştu. Bu hastaların altısında (%40) kaçak herhangi bir müdahaleye gerek kalmadan kapandı, sekizinde (%53) ise 10 günden fazla sürdü ve günlük debi 100 cc’nin üzerinde idi. Bu olgulara endoskopik sfinkterotomi uygulandı. Mortalite oranı %4 (n=2) olarak tespit edildi. Sonuç: Hidatik kist rüptürü karaciğerde kistik kitlesi olan ve intraperitoneal serbest sıvısı bulunan travma hastalarında akılda bulundurulması gereken bir durumdur. Bu hastalarda anaflaktik reaksiyon riski olduğu göz önüne alınarak hızla müdahale edilmelidir. Karaciğer kist hidatik cerrahisi sonrasında safra fistülü gelişen hastalarda endoskopik sfinkterotomi etkin bir tedavi yöntemidir

Single Centre Experience: Bening and Malign Hematological Patients with COVID-19

Introduction Coronavirus disease 2019 (COVID-19) were declared as pandemic by World Health Organization. With this study, we aimed to define our patients who were followed up with malign or benign hematological diagnoses and diagnosed with COVID-19; determine the distribution of this infection in patient groups and contribute to the literature by creating descriptive statistics with its clinical and demographic features. Patients and methods: It is planned to retrospectively examine patients with a history of COVID-19 who were followed up in Hematology Department of Dışkapı Yıldırım Beyazıt Training and Research Hospital with benign and malignant diagnoses. Results: 88 patients who had COVID-19 infection while being followed in our clinic due to hematological diseases were included in the study. 77 patients had been followed by hematologic malignancies and 11 patients had been followed by benign hematological disease.In the group with malignancy, COVID was found most frequently in patients diagnosed with Philadelphia chromosome negative myeloproliferative neoplasms (22%), nonhodgkin lymphoma (19%) and multiple myeloma (16%). ITP (64%) was the most common disease in patients with benign hematological disorder who had COVID history. 52 (67%) of the malignant cases and 8 (73%) of the bening cases were found to be followed up with the disease in remission. The all patient's most common symptoms at COVID-19 diagnosis were fever (77%), cough (70%) and weakness (65%). 45% of the patients were isolated at home, 48% were required hospitalization. 49% of patients had mild; 27% had moderate and 24% had severe COVID-19 infection. Almost all of the patients in the moderate and severe disease group were followed up in patients diagnosed with malignant hematological disease. 16 (18%) patients received mechanical ventilation and 16 (18%) patients was transferred intensive care unit. All of the patients who were intubated and needed intensive care were diagnosed with malignant hematological disease. 17 patients died due to COVID-19 infection. The mortality rate was 22% in patients with diagnosis of malignant hematological diseases, and 19% when all patients (malignant and bening) were included. Conclusion: In conclusion, the COVID-19 pandemic is a problem all over the world. Determining the course of the disease in certain diagnostic groups is important in the management of both the main disease and the COVID-19 infection. Therefore, the contribution of such recording studies to the literature is important and valuable

Mammary tuberculosis – importance of recognition and differentiation from that of a breast malignancy: report of three cases and review of the literature

<p>Abstract</p> <p>Background</p> <p>While tuberculosis of the breast is an extremely uncommon entity seen in western populations, it accounts for up to 3% of all treatable breast lesions in developing countries.</p> <p>Case presentations</p> <p>We reviewed three female cases of mammary tuberculosis that were diagnosed and treated in Turkey during the same calendar year. All three patients presented with a painful breast mass. In all cases, fine needle aspiration was nondiagnostic for mammary tuberculosis. However, the diagnosis of mammary tuberculosis was confirmed by histopathologic evaluation at the time of open surgical biopsy. All three patients were treated with antituberculous therapy for six months. At the end of the treatment period, each patient appeared to be clinically and radiologically without evidence of residual disease.</p> <p>Conclusion</p> <p>The diagnosis of mammary tuberculosis rests on the appropriate clinical suspicion and the histopathologic findings of the breast lesion. Its recognition and differentiation from that of a breast malignancy is absolutely necessary. Antituberculous chemotherapy, initiated immediately upon diagnosis, forms the mainstay of treatment for mammary tuberculosis.</p