Ventilator-Associated Pneumonia and Causative Microorganisms in Intensive Care Unit: A Two Year Retrospective Analysis

Conclusion: Intermittent analyses and antibiotic susceptibilities of VAP causative microorganisms are important factors for scheduling appropriate empirical antibiotic treatment and detection of correct infection control strategies in ARICU. As a consequently, if VAP was suspected, empirical antibiotic therapy should be planned against gram-negative microorganisms

The relation of BRAF V600E Mutation and microsatellite instability in colorectal carcinomas

WOS: 000310364801544

Anesthetic Techniques in Octogenarians and Older Undergoing Orthopedic Surgery for Hip Fracture

Objectives: Hip fracture is common orthopedic problems for patients aged 80 years and older. Because of their decreased cardiopulmonary capacity, an optimal anesthetic technique should be chosen by anesthesiologists. The purpose of the present study is to analyze anesthetic techniques and related postoperative mortality in octogenarians and older who underwent hip fractures surgery. Patients and Methods: We analyzed hip fracture surgeries and identified patients aged 80 years and older between January 2012 and December 2013. Patient age, gender, coexisting diseases, American Society of Anesthesiologists (ASA) Physical Status classification, anesthetic technique, hematocrit, hemoglobin, total lymphocyte count (TLC), the length of surgery, intraoperative blood transfusion requirements, postoperative discharge ward, the length of postoperative hospital stay, and postoperative status were recorded. Results: We retrospectively identified 106 patients aged 80 years and older underwent hip fracture surgeries. Six (5.6%), 36 (34.0%), 2 (1.9%), 53 (50.0%), and 9 (8.5%) of procedures were performed under general anesthesia (GA), spinal anesthesia (SA), epidural anesthesia, combined spinal-epidural anesthesia (CSEA), and peripheral nerve block (PNB), respectively. The postoperative 7 and 30-day mortality were 6.6% and 10.4%, respectively. Age, gender, ASA, hematocrit, hemoglobin, TLC, discharge to the ward, the length of postoperative hospital stay, and the postoperative mortality rates were similar between the GA, SA, CSEA, and PNB. There was no relationship between postoperative mortality and anesthetic technique. Conclusion: In octogenarians and older, the postoperative mortality is higher after hip fracture and is not associated with the anesthetic technique

The BRAF V600E mutation and microsatellite instability in colorectal carcinomas

29th Congress of the International-Academy-of-Pathology -- SEP 30-OCT 05, 2012 -- Cape Town, SOUTH AFRICAWOS: 000308126900275…Int Acad Patho

Comparison Of Early-Stage High-Grade Serous Primary Fallopian Tube Cancers and Epithelial Ovarian Cancers: A Multicenter Study

WOS: 000398884100006PubMed ID: 28376498Introduction: We compared the disease free-survival (DFS) and overall survival (OS) rates of patients with high-grade serous primary fallopian tube cancer (HG-sPFTC) and high-grade serous epithelial ovarian cancer (HG-sEOC). Methods: 22 early-stage cancer patients (International Federation of Gynecology and Obstetrics (FIGO) stages I-II) with HG-sPFTC were retrospectively evaluated. In addition, 44 control patients diagnosed with HG-sEOC were matched to these patients with respect to tumor stage at diagnosis. All patients underwent complete surgical staging, followed by adjuvant chemotherapy. Kaplan-Meier curves were used to generate survival data. Results: The mean age of HG-sPFTC patients was 59.4 +/- 6.2 years, and that of HG-sEOC patients 55.2 +/- 11.0 years (p = 0.002). All patients underwent 6 cycles of platinum-based adjuvant chemotherapy. All operations were optimal. The 5-year DFSs were 77.3% for HG-sPFTC patients and 75% for HG-sEOC patients (p = 1.00).The 5-year OS rates were 81.8% in women with HG-sPFTC and 77.3% in those with HG-sEOC (p = 0.75). Conclusion: The DFS and OS rates of patients with early-stage (FIGO stages I and II) HG-sPFTC and HG-sEOC were similar. The surgical and adjuvant therapy management of these malignancies should be similar. (C) 2017 S. Karger GmbH, Freibur

Borderline ovarian tumors: clinical characteristics, management, and outcomes - a multicenter study

Background: The optimal surgical management and staging of borderline ovarian tumors (BOTs) are controversial. Institutions have different surgical approaches for the treatment of BOTs. Here, we performed a retrospective review of clinical characteristics, surgical management and surgical outcomes, and sought to identify variables affecting disease-free survival (DFS) and overall survival (OS) in patients with BOTs