23 research outputs found

    Primary hyperparathyroidism diagnosed after surgical ablation of a costal mass mistaken for giant-cell bone tumor: a case report

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    <p>Abstract</p> <p>Introduction</p> <p>Primary hyperparathyroidism is a common endocrine disorder characterized by elevated parathyroid hormone levels, which cause continuous osteoclastic bone resorption. Giant cell tumor of bone is an expansile osteolytic tumor that contains numerous osteoclast-like giant cells. There are many similarities in the radiological and histological features of giant cell tumor of bone and brown tumor. This is a rare benign focal osteolytic process most commonly caused by hyperparathyroidism.</p> <p>Case presentation</p> <p>We report the unusual case of a 40-year-old Caucasian woman in which primary hyperparathyroidism was diagnosed after surgical ablation of a costal mass. The mass was suspected of being neoplastic and histopathology was compatible with a giant cell tumor of bone. On the basis of the biochemical results (including serum calcium, phosphorous and intact parathyroid hormone levels) primary hyperparathyroidism was suspected and a brown tumor secondary to refractory hyperparathyroidism was diagnosed.</p> <p>Conclusions</p> <p>Since giant cell tumor is a bone neoplasm that has major implications for the patient, the standard laboratory tests in patients with bone lesions are important for a correct diagnosis.</p

    The conditions for which geometric mean method revealed more accurate calculation of relative renal function in DMSA scintigraphy

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    Annual Congress of the European-Association-of-Nuclear-Medicine -- SEP 04-08, 2004 -- Helsinki, FINLANDWOS: 000223419901071…European Assoc Nucl Me

    The conditions for which the geometric mean method revealed a more accurate calculation of relative renal function in Tc-99m-DMSA scintigraphy

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    WOS: 000227263200011PubMed ID: 15657508Aims (1) To compare the results of calculating relative renal function (RRF) by using only posterior images (POST) with the geometric mean (GM) through both anterior and posterior imaging on dimercaptosuccinic acid (DMSA) scintigraphy. (2) To determine whether there was an age-related difference between them and whether some renal pathologies or asymmetrical renal function cause an error in the RRF calculation by using posterior images only. Methods Eight hundred and ninety-one DMSA scans were studied retrospectively. The patients were divided into five age groups: group I, less than or equal to 2 years; group II, > 2 to less than or equal to 5 years; group III > 5 to less than or equal to 10 years; group IV, > 10 to less than or equal to 18 years; and group V, > 18 years. The RRF of the right kidney (RKF) was calculated from the POST and GM counts. The differences between RKFGM and RKFPOST were calculated in all the patients. Results Among the 891 patients, nine had malrotated or malpositioned kidneys, 373 had renal pathologies of pyelonephritis, hydronephrosis, cortical scarring and atrophy, 247 had asymmetrically functioning kidneys and 509 had normal kidneys. When the patients were analysed according to different age groups, significant differences were found between all groups (P 0.05) with the Ftest. The clinically meaningful RRF variance ( greater than or equal to 5 % difference between two methods) rate differed significantly between groups I, II and III, and groups IV and V (chi-squared test, P < 0.05). In patients age

    Incidental detection of a vertebral body hemangioma on three-phase bone scintigraphy

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    WOS: 000083936200028PubMed ID: 10595494
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