15 research outputs found
Monitoring of Milk Quality With Disposable Taste Sensor.
A disposable screen-printed multi channel taste sensor composed of several types of lipid as transducers and a computer as data analyzer could detect taste in a manner similar to human gustatory sensation
An in vitro Comparison of Bond Strength of Different Sealers/Obturation Systems to Root Dentin Using the Push-Out Test at 2 Weeks and 3 Months after Obturation
Objective: To evaluate the push-out bond strength and failure modes of different sealers/obturation systems to intraradicular dentin at 2 weeks and 3 months after obturation compared to AH Plus®/gutta-percha. Materials and Methods: A total of 180 root slices from 60 single-canal anterior teeth were prepared and assigned to 5 experimental groups (n = 36 in each group), designated as G1 (AH Plus®/gutta-percha), G2 (TotalFill BC™ sealer/BC-coated gutta-percha), G3 (TotalFill BC™ sealer/gutta-percha), G4 (EndoREZ® sealer/EndoREZ®-coated gutta-percha), and G5 (EndoREZ® sealer/gutta-percha). Push-out bond strengths of 18 root slices in each group were assessed at 2 weeks and the other 18 at 3 months after obturation using a universal testing machine. Data were analyzed using repeated measures ANOVA. An independent t test was used to compare the mean push-out bond strength for each group at 2 weeks and 3 months after obturation. Results: The mean push-out bond strengths of G4 and G5 were significantly lower than those of G1, G2, and G3 (p < 0.05) at both 2 weeks (G1: 1.46 ± 0.29 MPa, G2: 1.74 ± 0.43 MPa, G3: 1.74 ± 0.43 MPa, G4: 0.66 ± 0.31 MPa, G5: 0.74 ± 0.47 MPa) and 3 months after obturation (G1: 1.70 ± 1.05 MPa, G2: 3.69 ± 1.20 MPa, G3: 2.84 ± 0.83 MPa, G4: 0.14 ± 0.05 MPa, G5: 0.24 ± 0.10 MPa). The mean push-out bond strengths of G2 (3.69 ± 1.20 MPa) and G3 (2.84 ± 0.83 MPa) were higher at 3 months compared to 2 weeks after obturation (G2: 1.74 ± 0.43 MPa, G3: 1.33 ± 0.29 MPa). Conclusion: The TotalFill BC™ obturation system (G2) and the TotalFill BC™ sealer/gutta-percha (G3) showed comparable bond strength to AH Plus®. Their bond strength increased over time, whereas the EndoREZ® obturation system (G4) and EndoREZ sealer (G5) had low push-out bond strength which decreased over time
Liver alanine catabolism promotes skeletal muscle atrophy and hyperglycaemia in type 2 diabetes.
Both obesity and sarcopenia are frequently associated in ageing, and
together may promote the progression of related conditions such as
diabetes and frailty. However, little is known about the
pathophysiological mechanisms underpinning this association. Here we
uncover dysregulated systemic alanine metabolism and hyper-expression of
the alanine transaminases (ALT) in the liver of obese/diabetic mice and
humans. Hepatocyte-selective silencing of both ALT enzymes revealed a
clear role in systemic alanine clearance which related to glycemic
control. In obese/diabetic mice, not only did silencing both ALT enzymes
retard hyperglycemia, but also reversed skeletal muscle atrophy. This
was due to a rescue of depressed skeletal muscle protein synthesis, with
a liver-skeletal muscle amino acid metabolic crosstalk exemplified by
ex vivo experiments. Mechanistically, chronic liver glucocorticoid and
glucagon signaling driven liver alanine catabolism promoted
hyperglycemia and skeletal muscle wasting. Taken together, here we
reveal an endocrine-hepato-muscular metabolic cycle linking
hyperglycemia and skeletal muscle atrophy in type 2 diabetes
Psoriasis in patients older than 65 years. A comparative study with younger adult psoriatic patients
The malay lexicon project: A database of lexical statistics for 9,592 words
10.3758/BRM.42.4.992Behavior Research Methods424992-100