Spatial-Spectral Manifold Embedding of Hyperspectral Data

In recent years, hyperspectral imaging, also known as imaging spectroscopy, has been paid an increasing interest in geoscience and remote sensing community. Hyperspectral imagery is characterized by very rich spectral information, which enables us to recognize the materials of interest lying on the surface of the Earth more easier. We have to admit, however, that high spectral dimension inevitably brings some drawbacks, such as expensive data storage and transmission, information redundancy, etc. Therefore, to reduce the spectral dimensionality effectively and learn more discriminative spectral low-dimensional embedding, in this paper we propose a novel hyperspectral embedding approach by simultaneously considering spatial and spectral information, called spatial-spectral manifold embedding (SSME). Beyond the pixel-wise spectral embedding approaches, SSME models the spatial and spectral information jointly in a patch-based fashion. SSME not only learns the spectral embedding by using the adjacency matrix obtained by similarity measurement between spectral signatures, but also models the spatial neighbours of a target pixel in hyperspectral scene by sharing the same weights (or edges) in the process of learning embedding. Classification is explored as a potential strategy to quantitatively evaluate the performance of learned embedding representations. Classification is explored as a potential application for quantitatively evaluating the performance of these hyperspectral embedding algorithms. Extensive experiments conducted on the widely-used hyperspectral datasets demonstrate the superiority and effectiveness of the proposed SSME as compared to several state-of-the-art embedding methods

Oxidation Degradation of Rhodamine B in Aqueous by UV

The UV photolysis of persulfate (S2O8 2−) is a novel advanced oxidation technologies (AOTs), which leads to the formation of strong oxidizing radicals, sulfate radicals (SO4 •−). The effect of oxidant S2O8 2− concentration, initial dye concentration, initial pH of solution, and various inorganic anions (Cl−, H2PO4 −, and HCO3 −) were investigated using Rhodamine B (RhB), a kind of xanthene dye, as a model pollutant. With the increase of oxidant S2O8 2−, more SO4 •− produced to attack RhB molecules and result in the increase of RhB degradation. While the improvement was not sustained above a critical value, beyond which degradation rate does not increase. Initial pH of solution had great effect on the RhB degradation rate during UV/S2O8 2− system. SO4 •− is rather stable in acidic solutions, while increasing system pH results in the transformation of SO4 •− to •OH. The effects of three inorganic anions (Cl−, H2PO4 −, and HCO3 −) all had some negative effect on the degradation of RhB. Based on the RhB solution changes of the UV-vis absorption intensity during the UV/S2O8 2− treatment, decolorization of RhB accompanied the destruction of aromatic ring structures of RhB molecules

Synthesis, Biological Evaluation of Fluorescent 23-Hydroxybetulinic Acid Probes, and Their Cellular Localization Studies

© 2018 American Chemical Society. 23-Hydroxybetulinic acid (23-HBA) is a complex lupane triterpenoid, which has attracted increasing attention as an anticancer agent. However, its detailed mechanism of anticancer action remains elusive so far. To reveal its anticancer mode of action, a series of fluorescent 23-HBA derivatives conjugated with coumarin dyes were designed, synthesized, and evaluated for their antiproliferative activities. Subcellular localization and uptake profile studies of representative fluorescent 23-HBA probe 26c were performed in B16F10 cells, and the results suggested that probe 26c was rapidly taken up into B10F10 cells in a dose-dependent manner and mitochondrion was the main site of its accumulation. Further mode of action studies implied that the mitochondrial pathway was involved in 23-HBA-mediated apoptosis. Together, our results provided new clues for revealing the molecular mechanism of natural product 23-HBA for its further development into an antitumor agent

(1R,3S,5R,6S)-6-Acet­oxy-3-(4-methyl­phenyl­sulfon­yloxy)tropane

In the title compound [systematic name: (1R,3S,5R,6S)-8-methyl-3-(4-methyl­phenyl­sulfon­yloxy)-8-aza­bicyclo­[3.2.1]octan-6-yl acetate], C17H23NO5S, the fused piperidine ring exists in a chair conformation with the N atom and one C atom displaced by 0.876 (2) and −0.460 (3) Å, respectively, on opposite sides of the mean plane defined by the other four atoms. The fused pyrrolidine ring adopts an envelope conformation with the N atom deviating by 0.644 (3) Å from the mean plane of the other four atoms