An Analysis Oncrude Oil Price Mutation in View of Zeeman's Catastrophe Machine

AbstractWith the acceleration of internationalmarket integration and the frequent outbreak of international political and economic events, the volatility of oil priceshas continued toincrease in recent years. As the main source of energy, crude oil plays an important role in the development of a country's economy. Therefore, it is meaningful to study the mutation of oil prices. Based on the Zeeman's catastrophe machine, USDX and excess demand are selected as two main factors to construct the catastrophe model, which helps to explain the structural relationship between USDX and excess demand when the crude oil price mutates

Numerical simulation of high frequency guided wave testing for anchor bolt defects

Previous research has confirmed that only high-frequency guided waves larger than 1 MHz have the minimum attenuation detection mode for anchor bolt widely used in underground projects. However, due to the complexity of numerical simulation of high-frequency guided waves, the research results are concentrated on experimental testing, which makes the research on propagation characteristics of high-frequency guided waves very limited. In order to explore the propagation of high-frequency guided wave and apply it to the on-site inspection of anchorage quality, the numerical model of anchor bolt is established by using ANSYS/LS–DYNA finite element software through parameter optimization. By analyzing the influence of different anchor thickness on the wave shape, the minimum outer diameter that can replace the field infinite anchor thickness model with the numerical simulation finite size model is obtained; In theory, the guided wave mainly propagates forward along the interior of the steel rod, and the bolt radial reflects the waveguide structure shape. Therefore, the bolt radial grid is set the densest, and the anchor body radial grid and the bar axial grid are set relatively sparse, in order to minimize the number of elements; In view of the different dispersion characteristics of guided waves with different head wave widths, the propagation process of guided waves in non-defective and defective bolts was studied, and the optimal head wave width was 0.04 ms; Based on the above three optimized parameters, the numerical models of the complete anchor bolt and the anchor bolt with defects are established respectively. The numerical simulation results are highly consistent with the laboratory test results in the literature, which proves that the numerical model established is correct and effective, and truly realizes the accurate simulation of high-frequency guided waves in the propagation application of the anchor bolt under the limited computing resources. On this basis, the anchor bolt model with different defect characteristics is built, and the defect location and depth are studied. The results show that the high frequency guided wave with specific frequency can accurately locate the steel rod defects, and the defect area can be roughly determined according to the ratio of defect echo amplitude to bottom echo amplitude

Audio-Visual Instance Segmentation

In this paper, we propose a new multi-modal task, namely audio-visual instance segmentation (AVIS), in which the goal is to identify, segment, and track individual sounding object instances in audible videos, simultaneously. To our knowledge, it is the first time that instance segmentation has been extended into the audio-visual domain. To better facilitate this research, we construct the first audio-visual instance segmentation benchmark (AVISeg). Specifically, AVISeg consists of 1,258 videos with an average duration of 62.6 seconds from YouTube and public audio-visual datasets, where 117 videos have been annotated by using an interactive semi-automatic labeling tool based on the Segment Anything Model (SAM). In addition, we present a simple baseline model for the AVIS task. Our new model introduces an audio branch and a cross-modal fusion module to Mask2Former to locate all sounding objects. Finally, we evaluate the proposed method using two backbones on AVISeg. We believe that AVIS will inspire the community towards a more comprehensive multi-modal understanding

Mechanotransduction through protein stretching

Cells sense and respond to subtle changes in their physicality, and via a myriad of different mechanosensitive processes, convert these physical cues into chemical and biochemical signals. This process, called mechanotransduction, is possible due to a highly sophisticated machinery within cells. One mechanism by which this can occur is via the stretching of mechanosensitive proteins. Stretching proteins that contain force-dependent regions results in altered geometry and dimensions of the connections, as well as differential spatial organization of signals bound to the stretched protein. The purpose of this mini-review is to discuss some of the intense recent activity in this area of mechanobiology that strives to understand how protein stretching can influence signaling outputs and cellular responses

Recombinational landscape of porcine X chromosome and individual variation in female meiotic recombination associated with haplotypes of Chinese pigs

<p>Abstract</p> <p>Background</p> <p>Variations in recombination fraction (θ) among chromosomal regions, individuals and families have been observed and have an important impact on quantitative trait loci (QTL) mapping studies. Such variations on porcine chromosome X (SSC-X) and on other mammalian chromosome X are rarely explored. The emerging assembly of pig sequence provides exact physical location of many markers, facilitating the study of a fine-scale recombination landscape of the pig genome by comparing a clone-based physical map to a genetic map. Using large offspring of F₁females from two large-scale resource populations (Large White ♂ × Chinese Meishan ♀, and White Duroc ♂ × Chinese Erhualian ♀), we were able to evaluate the heterogeneity in θ for a specific interval among individual F₁females.</p> <p>Results</p> <p>Alignments between the cytogenetic map, radiation hybrid (RH) map, genetic maps and clone map of SSC-X with the physical map of human chromosome X (HSA-X) are presented. The most likely order of 60 markers on SSC-X is inferred. The average recombination rate across SSC-X is of ~1.27 cM/Mb. However, almost no recombination occurred in a large region of ~31 Mb extending from the centromere to Xq21, whereas in the surrounding regions and in the Xq telomeric region a recombination rate of 2.8-3.3 cM/Mb was observed, more than twice the chromosome-wide average rate. Significant differences in θ among F₁females within each population were observed for several chromosomal intervals. The largest variation was observed in both populations in the interval <it>UMNP71-SW1943</it>, or more precisely in the subinterval <it>UMNP891-UMNP93</it>. The individual variation in θ over this subinterval was found associated with F₁females' maternal haplotypes (Chinese pig haplotypes) and independent of paternal haplotype (European pig haplotypes). The θ between <it>UMNP891 </it>and <it>UMNP93 </it>for haplotype 1122 and 4311 differed by more than fourteen-fold (10.3% vs. 0.7%).</p> <p>Conclusions</p> <p>This study reveals marked regional, individual and haplotype-specific differences in recombination rate on SSC-X. Lack of recombination in such a large region makes it impossible to narrow QTL interval using traditional fine-mapping approaches. The relationship between recombination variation and haplotype polymorphism is shown for the first time in pigs.</p

A Platform for Far-Infrared Spectroscopy of Quantum Materials at Millikelvin Temperatures

Optical spectroscopy of quantum materials at ultralow temperatures is rarely explored, yet it may provide critical characterizations of quantum phases not possible using other approaches. We describe the development of a novel experimental platform that enables optical spectroscopic studies, together with standard electronic transport, of materials at millikelvin temperatures inside a dilution refrigerator. The instrument is capable of measuring both bulk crystals and micron-sized two-dimensional van der Waals materials and devices. We demonstrate the performance by implementing photocurrent-based Fourier transform infrared spectroscopy on a monolayer WTe$_2$ device and a multilayer 1T-TaS$_2$ crystal, with a spectral range available from near-infrared to terahertz range and in magnetic fields up to 5 T. In the far-infrared regime, we achieve spectroscopic measurements at a base temperature as low as ~ 43 mK and a sample electron temperature of ~ 450 mK. Possible experiments and potential future upgrades of this versatile instrumental platform are envisioned.Comment: 13 pages, 6 figures, typos correcte

The focal adhesion protein talin is a mechanically gated A-kinase anchoring protein

Protein kinase A (PKA) is a ubiquitous, promiscuous kinase whose activity is specified through subcellular localization mediated by A-kinase anchoring proteins (AKAPs). PKA has complex roles as both an effector and a regulator of integrin-mediated cell adhesion to extracellular matrix (ECM). Recent observations demonstrate that PKA is an active component of focal adhesions (FA), suggesting the existence of one or more FA AKAPs. Using a promiscuous biotin ligase fused to PKA type-IIα regulatory (RIIα) subunits and subcellular fractionation, we identify the archetypal FA protein talin1 as an AKAP. Talin is a large, mechanosensitive scaffold that directly links integrins to actin filaments and promotes FA assembly by recruiting additional components in a force-dependent manner. The rod region of talin1 consists of 62 α-helices bundled into 13 rod domains, R1 to R13. Direct binding assays and NMR spectroscopy identify helix41 in the R9 subdomain of talin as the PKA binding site. PKA binding to helix41 requires unfolding of the R9 domain, which requires the linker region between R9 and R10. Experiments with single molecules and in cells manipulated to alter actomyosin contractility demonstrate that the PKA–talin interaction is regulated by mechanical force across the talin molecule. Finally, talin mutations that disrupt PKA binding also decrease levels of total and phosphorylated PKA RII subunits as well as phosphorylation of VASP, a known PKA substrate, within FA. These observations identify a mechanically gated anchoring protein for PKA, a force-dependent binding partner for talin1, and a potential pathway for adhesion-associated mechanotransduction

Surface-Confined Two-Dimensional Crystal Growth on a Monolayer

Conventional vapor deposition or epitaxial growth of two-dimensional (2D) materials and heterostructures is conducted in a large chamber in which masses transport from the source to the substrate. Here we report a chamber-free, on-chip approach for growing a 2D crystalline structures directly in a nanoscale surface-confined 2D space. The method is based on a surprising discovery of a rapid, long-distance, non-Fickian transport of a uniform layer of atomically thin palladium (Pd) on a monolayer crystal of tungsten ditelluride (WTe2), at temperatures well below the known melting points of all materials involved. The resulting nanoconfined growth realizes a controlled formation of a stable new 2D crystalline material, Pd7WTe2 , when the monolayer seed is either free-standing or fully encapsulated in a van der Waals stack. The approach is generalizable and highly compatible with nanodevice fabrication, promising to expand the library of 2D materials and their functionalities